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anti-SRY (Sex Determining Region Y)-Box 8 (SOX8) Antibodies

SOX8 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX8 Kits (9) and SOX8 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SOX8 30812 P57073
SOX8 302993  
SOX8 20681 Q04886
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Top anti-SOX8 Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-SOX8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated WB SOX8 Antibody (Center)  western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SOX8 antibody detected the SOX8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry (IHC) analyzes of Sox-8/9/17/18 antibody in paraffin-embedded human brain tissue. Western blot (WB) analysis of Sox-8/9/17/18 antibody in extracts from COS7 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 14 Days
$369.79
Details
Human Rabbit Un-conjugated IHC (fro), WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details

SOX8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SOX8 Antibodies

  1. Dog (Canine) Polyclonal SOX8 Primary Antibody for WB - ABIN2792566 : Wissmüller, Kosian, Wolf, Finzsch, Wegner: The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors. in Nucleic acids research 2006 (PubMed)

  2. Human Polyclonal SOX8 Primary Antibody for ELISA, WB - ABIN238624 : ODonnell, Hong, Huang, Delnicki, Saint-Jeannet: Functional analysis of Sox8 during neural crest development in Xenopus. in Development (Cambridge, England) 2006 (PubMed)

More Antibodies against SOX8 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 8 (SOX8) interaction partners

  1. In non-small cell lung cancer, SOX8 expression was elevated, and correlated with tumor size, lymph node metastasis, clinical stage and differentiation classification.

  2. Suggest that miRNA-124 may regulate non-small cell lung carcinoma cell proliferation via decreasing SOX8.

  3. SOX8 mRNA levels decrease during in vitro dedifferentiation of human articular chondrocytes and increase during chondrogenic differentiation of mesenchymal stromal cells.

  4. SOX8 promotes cancer cell proliferation and its expression is correlated with elevated beta-catenin (show CTNNB1 Antibodies) levels in hepatocellular carcinoma

  5. The SOX8 single nucleotide polymorphism, rs2744148, is associated with increased genetic risk for multiple sclerosis.

  6. Quantitative changes of enteric glia represented by SOX8 provide a basis for pathological assessment of glial proliferation and/or degeneration in the diseased gut (show GUSB Antibodies).

  7. SOX2 (show SOX2 Antibodies) and SOX17 (show SOX17 Antibodies) expression patterns can distinguish between seminoma and embryonal carcinoma, and this distinction may be diagnostically useful.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 8 (SOX8) interaction partners

  1. These results suggest that Sox8 is essential in Sertoli cells for germ cell differentiation, partly by controlling the microenvironment of the seminiferous epithelium.

  2. combined RNA profiling signals, motif predictions and network data identified putative SOX8/SOX9 (show SOX9 Antibodies) target genes in Sertoli cells and yielded insight into regulatory interactions that depend upon these transcription factors

  3. Sox9 (show SOX9 Antibodies) and Sox8 maintain integrity of the basal lamina to prevent testis cord disintegration and both factors actively suppress the ovarian program during early testis development.

  4. Seven regions near the Sox8 gene as potential enhancers, were identified.

  5. SOX8 has a role in testis differentiation in mice and synergizes with SF1 (show SF1 Antibodies) to activate the Amh (show AMH Antibodies) promoter in vitro

  6. Sox8 acts as a specific negative regulator of skeletal muscle differentiation, possibly by interfering with the function of myogenic basic helix-loop-helix proteins

  7. Results suggest that Sox8 reinforces Sox9 (show SOX9 Antibodies) function in testis differentiation of mice.

  8. Sox8-deficient mice thus exhibited a similar, but less severe phenotype than did Sox10 (show SOX10 Antibodies)-deficient mice wiwth regard to oligodendrocyte differentiation.

  9. The defects in enteric nervous system development of mice with Sox10 (show SOX10 Antibodies) and Sox8 mutations are caused by a reduction of the pool of undifferentiated vagal neural crest cells.

  10. Sox8 is a negative regulator of osteoblast differentiation.

SOX8 Antigen Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome).

Gene names and symbols associated with SOX8

  • SRY (sex determining region Y)-box 8 (SOX8) antibody
  • SRY (sex determining region Y)-box 8 (Sox8) antibody
  • SRY (sex determining region Y)-box 8 (sox8) antibody
  • SRY-box containing gene 8 (Sox8) antibody

Protein level used designations for SOX8

transcription factor SOX-8 , SRY-box containing gene 8 , transcription factor Sox-8 , SOX8 transcription factor

GENE ID SPECIES
30812 Homo sapiens
302993 Rattus norvegicus
399214 Xenopus laevis
490082 Canis lupus familiaris
395483 Gallus gallus
530317 Bos taurus
20681 Mus musculus
Selected quality suppliers for anti-SOX8 (SOX8) Antibodies
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