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May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination (By similarity). Additionally we are shipping SSU72 Antibodies (14) and many more products for this protein.
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Human SSU72 Protein expressed in Escherichia coli (E. coli) - ABIN667667
Dichtl, Blank, Ohnacker, Friedlein, Roeder, Langen, Keller: A role for SSU72 in balancing RNA polymerase II transcription elongation and termination. in Molecular cell 2002
Show all 2 references for 667667
Aurora B kinase (show AURKB Proteins) directly targets Ssu72 phosphatase for regulation of sister chromatid cohesion during early mitosis.
The pSer7 phosphatase activity of Ssu72 is approximately 4000-fold lower than its pSer5 phosphatase activity toward a peptide substrate
Data suggest that Ssu72 is a novel cohesin-binding protein capable of regulating cohesion between sister chromatid arms.
crystal structure at 2.4 A resolution of the amino-terminal domain (residues 30-340) of human symplekin (show SYMPK Proteins) in a ternary complex with the Pol II carboxy-terminal domain (CTD) Ser (show SIGLEC1 Proteins) 5 phosphatase Ssu72 and a CTD Ser (show SIGLEC1 Proteins) 5 phosphopeptide
Molecular cloning and characterization of functions of human ssu72.
the amino terminus of Pta1 (show CD226 Proteins) has an inhibitory effect and that this effect can be neutralized through the interaction with Ssu72.
May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination (By similarity).
CTD phosphatase SSU72
, RNA polymerase II subunit A C-terminal domain phosphatase SSU72