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ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5) ELISA Kits

Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. Additionally we are shipping ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 Antibodies (31) and ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ST3GAL5 ST3GAL5 8869 Q9UNP4
Anti-Mouse ST3GAL5 ST3GAL5 20454 O88829
Anti-Rat ST3GAL5 ST3GAL5 83505 Q68G12
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More ELISA Kits for ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 Interaction Partners

Human ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5) interaction partners

  1. this study indicated that sialylation involved in the development of MDR of AML (show RUNX1 ELISA Kits) cells probably through ST3GAL5 or ST8SIA4 (show ST8SIA4 ELISA Kits) regulating the activity of PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling and the expression of P-gp (show ABCB4 ELISA Kits) and MRP1 (show MDM4 ELISA Kits).

  2. Whole-exome sequencing of patients with salt and pepper syndrome shows a homozygous c.994G>A transition (p.E332K) in the ST3GAL5 gene.

  3. GM3 synthase deficiency, responsible for early-onset epilepsy syndrome, leads to a secondary respiratory chain dysfunction.

  4. Data demonstrate that valproic acid (VPA) transcriptionally regulates human GM3 synthase (hST3Gal V), which catalyzes ganglioside GM3 (show GRM6 ELISA Kits) biosynthesis in ARPE-19 human retinal pigment epithelial cells.

  5. GM3 exhibits the potential to regulate the allosteric structural transition from inactive to a signaling EGFR dimer, by preventing the autophosphorylation of the intracellular kinase domain in response to ligand binding

  6. In vivo expression of the transcript gives rise to two human ST3Gal-V isoforms with distinct characteristics.

  7. ST6Gal I (show ST6GAL1 ELISA Kits) and ST3Gal V were positively correlated with the high risk of pediatric acute leukemia.

  8. GM3 synthase overexpression results in reduced cell motility and in caveolin-1 (show CAV1 ELISA Kits) upregulation in human ovarian carcinoma cells

  9. GM3 synthase mRNA levels were significantly higher in differentiated human monocyte-derived macrophages compared to monocytes and in atherosclerotic aorta compared to normal aorta

  10. enhanced expression of GM3 synthase through protein kinase C (show PKC ELISA Kits) /extracellular regulated kinases-dependent cAMP-responsive element binding protein (show CREB1 ELISA Kits) activation by phorbol 12-myristate 13-acetate is associated with the differentiation of HL-60 cells

Mouse (Murine) ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5) interaction partners

  1. Functionally, the repression of St3gal5 suffices to elevate intercellular adhesion and expression of distinct junction-associated proteins, reminiscent of knockdown of Zeb1 (show ZEB1 ELISA Kits).

  2. ganglioside GM3 synthase has a role in siRNA-based spherical nucleic acid reversal of impaired wound healing in diabetic mice

  3. Results show that complete and partial deletion of the GM3 synthase gene exert distinct effects on the NP-C (Niemann-Pick disease Type C) phenotype.

  4. genes involved in the sphingolipids metabolism may be modifiers of cystogenesis, and suggest GM3 synthase as a new anti-cystic therapeutic target.

  5. Results suggest that complete, but not partial, inhibition of GM3 (show GRM6 ELISA Kits) synthesis results in robust activation of an alternate pathway that may compensate for the complete absence of the products of GM3 synthase.

  6. the age at death of the npc1 (show NPC1 ELISA Kits)(-/-) mouse can be significantly influenced by many factors, including differences in strain background, other inactivating gene mutations in Siat9 and lxrbeta (show NR1H2 ELISA Kits)

  7. GM3 synthase silencing suppressed lung metastasis in murine breast cancer cells. The molecular mechanism that underlies GM3 synthase mediated migration and invasion was inhibition of the phosphoinositide-3 kinase/Akt (show AKT1 ELISA Kits) pathway.

  8. The defect of hearing ability of GM3 synthase null mice could be attributed to the functional disorganization of the organ of Corti, and the expression of gangliosides, especially GM3 (show GRM6 ELISA Kits), during the maturation of the cochlea.

  9. zST3GalV-2 and mST3GalV are the enzymes responsible for the synthesis of GM4 in zebrafish and mice, respectively.

ST3 beta-Galactoside alpha-2,3-Sialyltransferase 5 (ST3GAL5) Antigen Profile

Antigen Summary

Ganglioside GM3 is known to participate in the induction of cell differentiation, modulation of cell proliferation, maintenance of fibroblast morphology, signal transduction, and integrin-mediated cell adhesion. The protein encoded by this gene is a type II membrane protein which catalyzes the formation of GM3 using lactosylceramide as the substrate. The encoded protein is a member of glycosyltransferase family 29 and may be localized to the Golgi apparatus. Mutation in this gene has been associated with Amish infantile epilepsy syndrome. Transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ST3GAL5

  • ST3 beta-galactoside alpha-2,3-sialyltransferase 5 (ST3GAL5) antibody
  • ST3 beta-galactoside alpha-2,3-sialyltransferase 5 (St3gal5) antibody
  • 3S-T antibody
  • SATI antibody
  • Siat9 antibody
  • SIATGM3S antibody
  • ST3GAL-V antibody
  • ST3GalV antibody
  • [a]2 antibody

Protein level used designations for ST3GAL5

CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase , GM3 synthase , ST3Gal V , alpha 2,3-sialyltransferase V , ganglioside GM3 synthase , lactosylceramide alpha-2,3-sialyltransferase , sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase; GM3 synthase) , ST3GalV , alpha2,3-sialyltransferase , sialyltransferase 9 , GM3-specific sialytransferase , mST3Gal V , sialyltransferase 9 (CMP-NeuAc:lactosylceramide alpha-2,3-sialyltransferase)

GENE ID SPECIES
8869 Homo sapiens
612022 Canis lupus familiaris
404164 Bos taurus
20454 Mus musculus
83505 Rattus norvegicus
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