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STEAP Family Member 2, Metalloreductase Proteins (STEAP2)

STEAP2 is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. Additionally we are shipping STEAP2 Antibodies (51) and STEAP2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
STEAP2 74051 Q8BWB6
STEAP2 261729 Q8NFT2
Rat STEAP2 STEAP2 312052  
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Top STEAP2 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

STEAP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for STEAP Family Member 2, Metalloreductase (STEAP2) Interaction Partners

Mouse (Murine) STEAP Family Member 2, Metalloreductase (STEAP2) interaction partners

  1. Stamp1 and Stamp2 (show STEAP4 Proteins) play critical roles in adipogenesis, but through different mechanisms.

Human STEAP Family Member 2, Metalloreductase (STEAP2) interaction partners

  1. Over-expression of STEAP2 is associated with prostate cancer progression.

  2. Data suggest that STAMP1 is required for prostate cancer growth.

  3. cloning and characterization of STAMP1, which is expressed in both normal prostate and prostate neoplasms

  4. STEAP2 is involved in the development of prostate cancer. As a cell-surface antigen (show CD53 Proteins), it is a potential diagnostic or therapeutic target in prostate cancer.

  5. Expression of STAMP2 (show STEAP4 Proteins), a gene highly similar to STAMP1 (STEAP2), in prostate cancer cells significantly increases cell growth and colony formation suggesting that STAMP2 (show STEAP4 Proteins) may have a role in cell proliferation.

  6. The murine ortholog, Steap2, is a ferrireductase, cupric reductase, and stimulates cellular uptake of both iron and copper in vitro.

STEAP2 Protein Profile

Protein Summary

This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with STEAP2

  • six transmembrane epithelial antigen of prostate 2 (Steap2)
  • STEAP family member 2, metalloreductase (STEAP2)
  • STEAP family member 2, metalloreductase (Steap2)
  • 4921538B17Rik protein
  • AI930049 protein
  • AW045895 protein
  • IPCA-1 protein
  • IPCA1 protein
  • PCANAP1 protein
  • PUMPCn protein
  • STAMP1 protein
  • STMP protein

Protein level used designations for STEAP2

metalloreductase STEAP2 , six-transmembrane epithelial antigen of prostate 2 , SixTransMembrane Protein of Prostate 1 , prostate cancer associated protein 1 , prostate cancer-associated protein 1 , protein up-regulated in metastatic prostate cancer , protein upregulated in metastatic prostate cancer , six transmembrane epithelial antigen of prostate 2 , six transmembrane epithelial antigen of the prostate 2

GENE ID SPECIES
74051 Mus musculus
261729 Homo sapiens
312052 Rattus norvegicus
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