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SUMO/sentrin Specific Peptidase Family Member 8 Proteins (SENP8)

SENP8 encodes a cysteine protease that is a member of the sentrin-specific protease family. Additionally we are shipping SUMO/sentrin Specific Peptidase Family Member 8 Antibodies (62) and SUMO/sentrin Specific Peptidase Family Member 8 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SENP8 71599 Q9D2Z4
SENP8 123228 Q96LD8
SENP8 315723 Q5FVJ8
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Top SUMO/sentrin Specific Peptidase Family Member 8 Proteins at antibodies-online.com

Showing 10 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,539.17
Details
Yeast Arabidopsis thaliana His tag   1 mg Log in to see 56 to 66 Days
$2,566.67
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$115.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SENP8 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,
Rat (Rattus)

Top referenced SUMO/sentrin Specific Peptidase Family Member 8 Proteins

  1. Human SENP8 Protein expressed in Escherichia coli (E. coli) - ABIN667489 : Reverter, Lima: A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. in Structure (London, England : 1993) 2004 (PubMed)
    Show all 2 references for ABIN667489

More Proteins for SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Interaction Partners

Arabidopsis thaliana SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) interaction partners

  1. mutants of a DEN1 homolog from Arabidopsis thaliana have no detectable defects in NEDD8 processing but do accumulate a broad range of NEDD8 conjugates. Neddylation may serve as a regulatory mechanism for cullin and non-cullin proteins. [DEN1]

Human SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) interaction partners

  1. In endothelial dysfunction, HDAC2 (show HDAC2 Proteins) levels were reciprocally regulated by ectopic expression of NEDD8 (show NEDD8 Proteins) and the de-NEDDylating enzyme SENP8.

  2. the expression of SENP8, SAE1 (show SAE1 Proteins), PIAS1 (show PIAS1 Proteins), PIAS2 (show PIAS2 Proteins) and ZMIZ1 is deregulated in the majority of PTC (show F9 Proteins) tissues, likely contributing to the PTC (show F9 Proteins) phenotype.

  3. Data indicate that overexpression of SENP8, a NEDD8 (show NEDD8 Proteins)-specific cysteine protease (show CTSB Proteins), resulted in deNEDDylation of E2F1 (show E2F1 Proteins) and promoted its transactivation activity at the p73 (show TP73 Proteins) gene.

  4. We analyzed whether CSN1 (show CSN1S1 Proteins) alone can increase DEN1 degradation in HeLa cells.these data suggest that the COP9 (show COPS8 Proteins) signalosome supports proteasome-dependent protein degradation of DEN1/DenA in fungi and in human cells.

  5. A role for SENP8 as a central regulator of the inflammatory process is identified using knockdown and overexpression approaches.

  6. the specificity of NEDD8 (show NEDD8 Proteins)-specific peptidase SENP8

  7. Data show that the stability of MDM2 (show MDM2 Proteins) is regulated by NEDD8 (show NEDD8 Proteins) pathway and identify NEDP1 that deneddylates MDM2 (show MDM2 Proteins), resulting in MDM2 (show MDM2 Proteins) destabilization concomitant with p53 (show TP53 Proteins) activation.

  8. NEDP1 is likely to play an important role in ubiquitin-mediated proteolysis by controlling the activity of SCF (show KITLG Proteins) complexes

  9. results suggest a unique role for NEDD8-specific protease 1(DEN1) in regulating the modification of cullin 1 (show CUL1 Proteins) by Nedd8 (show NEDD8 Proteins) protein

  10. X-ray structures of the human Nedd8-specific protease (show USP21 Proteins), Den1, in a complex with the inhibitor Nedd8 (show NEDD8 Proteins) aldehyde, thus revealing a model for the tetrahedral transition state intermediate generated during proteolysis

SUMO/sentrin Specific Peptidase Family Member 8 (SENP8) Protein Profile

Protein Summary

This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SENP8

  • SUMO/sentrin specific peptidase family member 8 (senp8-b)
  • NEDD8-specific protease 1 (AT5G60190)
  • SUMO/sentrin specific peptidase 8 (Senp8)
  • SUMO/sentrin specific peptidase family member 8 (SENP8)
  • SUMO/sentrin specific peptidase family member 8 (Senp8)
  • 9130010J17Rik protein
  • AU020827 protein
  • DEN1 protein
  • F15L12.8 protein
  • F15L12_8 protein
  • MGC84956 protein
  • NEDP1 protein
  • PRSC2 protein

Protein level used designations for SENP8

SUMO/sentrin specific peptidase family member 8 , NEDD8-specific protease 1 , SUMO/sentrin specific protease 8 , SUMO/sentrin specific protease family member 8 , deneddylase-1 , protease, cysteine, 2 (NEDD8 specific) , sentrin-specific protease 8 , sentrin/SUMO-specific protease SENP8 , NEDD8 specific-protease cysteine 2 , SUMO sentrin specific protease family member 8 , deneddylase 1 , protease, cysteine 2 , SUMO/sentrin specific peptidase 8 , Sumo1/sentrin/SMT3 specific peptidase 8

GENE ID SPECIES
735058 Xenopus laevis
836141 Arabidopsis thaliana
71599 Mus musculus
123228 Homo sapiens
315723 Rattus norvegicus
487631 Canis lupus familiaris
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