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anti-SUMO1 Activating Enzyme Subunit 1 (SAE1) Antibodies

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Additionally we are shipping SAE1 Proteins (20) and SAE1 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SAE1 57514 Q2M1Z3
SAE1 56459 Q9R1T2
SAE1 308384 Q6AXQ0
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Top anti-SAE1 Antibodies at antibodies-online.com

Showing 10 out of 126 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB The AOS1 C-term Pab (ABIN389081) is used in Western blot to detect AOS1 in mouse heart tissue lysate. Western blot analysis of AOS1 (arrow) using rabbit polyclonal AOS1 Antibody (C-term) (ABIN389081). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the AOS1 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chimpanzee Rabbit Un-conjugated EIA, IF, IHC (p), WB 0.5 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185082 staining (1µg/ml) of Jurkat lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to SAE1 on HeLa cell (antibody concentration 10 µg/mL). SAE1 monoclonal antibody (M01), clone 1G4-1G5 Western Blot analysis of SAE1 expression in HeLa. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SAE1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IHC (p), WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details

SAE1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-SAE1 Antibodies

  1. Human Monoclonal SAE1 Primary Antibody for IF, WB - ABIN395192 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in 2007 (PubMed)
    Show all 5 references for ABIN395192

  2. Chimpanzee Polyclonal SAE1 Primary Antibody for EIA, IF - ABIN401032 : Lois, Lima: Structures of the SUMO E1 provide mechanistic insights into SUMO activation and E2 recruitment to E1. in The EMBO journal 2005 (PubMed)
    Show all 4 references for ABIN401032

  3. Human Polyclonal SAE1 Primary Antibody for EIA, IHC (p) - ABIN357744 : Desterro, Rodriguez, Kemp, Hay: Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN357744

  4. Cow (Bovine) Polyclonal SAE1 Primary Antibody for EIA, WB - ABIN401467 : Gong, Li, Millas, Yeh: Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex. in FEBS letters 1999 (PubMed)
    Show all 3 references for ABIN401467

  5. Human Polyclonal SAE1 Primary Antibody for IHC (p), WB - ABIN389081 : Okuma, Honda, Ichikawa, Tsumagari, Yasuda: In vitro SUMO-1 modification requires two enzymatic steps, E1 and E2. in Biochemical and biophysical research communications 1999 (PubMed)
    Show all 3 references for ABIN389081

More Antibodies against SAE1 Interaction Partners

Human SUMO1 Activating Enzyme Subunit 1 (SAE1) interaction partners

  1. the expression of SENP8 (show SENP8 Antibodies), SAE1, PIAS1 (show PIAS1 Antibodies), PIAS2 (show PIAS2 Antibodies) and ZMIZ1 (show ZMIZ1 Antibodies) is deregulated in the majority of PTC (show F9 Antibodies) tissues, likely contributing to the PTC (show F9 Antibodies) phenotype.

  2. as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells.

  3. a four-generation pedigree with isolated terminal limb defects and a truncating mutation in ARHGAP31 (show ARHGAP31 Antibodies) underscores the relevance of sequencing ARHGAP31 (show ARHGAP31 Antibodies) in cases of isolated limb defects, irrespective of presence of a complete Adams-Oliver syndrome phenotype

  4. The focal adhesion-localized CdGAP (show ARHGAP31 Antibodies) regulates matrix rigidity sensing and durotaxis.

  5. Data demonstrate that cdGAP (show ARHGAP31 Antibodies) negatively regulates directed and random migration by controlling adhesion maturation and dynamics through the regulation of both adhesion assembly and disassembly.

  6. Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 (show RBBP8 Antibodies) antibody as marker of dermatomyositis.

  7. specific interaction between negatively charged phospholipid PI(3,4,5)P3 and the stretch of polybasic residues preceding the RhoGAP (show ARHGAP1 Antibodies) domain regulates CdGAP (show ARHGAP31 Antibodies) activity in vivo and is required for its cellular functions.

  8. Data show that the SAE2 (show RBBP8 Antibodies) subunit of the small ubiquitin-like modifier (SUMO (show SUMO1 Antibodies)) E1 is autoSUMOylated at residue Lys (show LYZ Antibodies)-236, and SUMOylation was catalyzed by Ubc9 (show UBE2I Antibodies) at several additional Lys (show LYZ Antibodies) residues surrounding the catalytic Cys (show DNAJC5 Antibodies)-173 of SAE2 (show RBBP8 Antibodies).

  9. loss of SAE1/2 activity drives synthetic lethality with Myc (show MYC Antibodies); inactivation of SAE2 (show RBBP8 Antibodies) leads to mitotic catastrophe and cell death upon Myc (show MYC Antibodies) hyperactivation; findings in Myc (show MYC Antibodies)-high breast cancers suggest low tumor SAE1 and SAE2 (show RBBP8 Antibodies) correlates metastasis-free survival

  10. Rho GTPase activating protein 31 (show ARHGAP31 Antibodies)

SAE1 Antigen Profile

Protein Summary

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Gene names and symbols associated with SAE1

  • Rho GTPase activating protein 31 (ARHGAP31) antibody
  • SUMO1 activating enzyme subunit 1 (SAE1) antibody
  • SUMO1 activating enzyme subunit 1 (Sae1) antibody
  • SUMO1 activating enzyme subunit 1 (sae1) antibody
  • 2400010M20Rik antibody
  • 2610044L12Rik antibody
  • AL033372 antibody
  • aos antibody
  • AOS1 antibody
  • Aos1p antibody
  • AW743391 antibody
  • CDGAP antibody
  • D7Ertd177e antibody
  • HSPC140 antibody
  • Sua1 antibody
  • Sua1p antibody
  • Uble1a antibody

Protein level used designations for SAE1

Cdc42 GTPase-activating protein , rho GTPase-activating protein 31 , SUMO-1 activating enzyme E1 N subunit , SUMO-1 activating enzyme subunit 1 , SUMO-activating enzyme subunit 1 , activator of SUMO1 , sentrin/SUMO-activating protein AOS1 , ubiquitin-like 1-activating enzyme E1A , ubiquitin-like protein SUMO-1 activating enzyme , ubiquitin-like (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme E1A , ubiquitin-like 1 (sentrin) activating enzyme subunit 1 , SUMO-activating enzyme E1 N subunit

GENE ID SPECIES
57514 Homo sapiens
10055 Homo sapiens
56459 Mus musculus
308384 Rattus norvegicus
505512 Bos taurus
476425 Canis lupus familiaris
100173973 Pongo abelii
443558 Xenopus laevis
Selected quality suppliers for anti-SAE1 (SAE1) Antibodies
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