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anti-SUMO1 Activating Enzyme Subunit 2 (UBA2) Antibodies

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. Additionally we are shipping SUMO1 Activating Enzyme Subunit 2 Proteins (5) and SUMO1 Activating Enzyme Subunit 2 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBA2 10054 Q9UBT2
UBA2 50995 Q9Z1F9
UBA2 308508  
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Top anti-SUMO1 Activating Enzyme Subunit 2 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-UBA2 C-term E616 Antibody (ABIN387913) is used in Western blot to detect UBA2 in Jurkat lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SAE2 in 293 cell lysate with SAE2 antibody at 0.25 μg/ml in (A) the absence and (B) the presence of blocking peptide. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Breast 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-UBA2 mouse monoclonal antibody (ABIN2454287) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY UBA2 (RC201288). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY UBA2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-UBA2. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from 293 cells, treated with UV 5', using Uba2 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Uba2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ICC, IF, WB ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using UBA2, antibody at 1:500 dilution. WB Image Sample (30 ug of whole cell lysate) A: Hela 7.5% SDS PAGE UBA2 antibody antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details

UBA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Rat (Rattus)
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Top referenced anti-SUMO1 Activating Enzyme Subunit 2 Antibodies

  1. Human Polyclonal UBA2 Primary Antibody for EIA, IHC (p) - ABIN356597 : Desterro, Rodriguez, Kemp, Hay: Identification of the enzyme required for activation of the small ubiquitin-like protein SUMO-1. in The Journal of biological chemistry 1999 (PubMed)
    Show all 3 references for ABIN356597

  2. Human Polyclonal UBA2 Primary Antibody for IHC (p), WB - ABIN387913 : Gong, Li, Millas, Yeh: Molecular cloning and characterization of human AOS1 and UBA2, components of the sentrin-activating enzyme complex. in FEBS letters 1999 (PubMed)
    Show all 3 references for ABIN387913

  3. Human Polyclonal UBA2 Primary Antibody for ELISA - ABIN185083 : Kanemaru, Saitoh: High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system. in Bioscience, biotechnology, and biochemistry 2013 (PubMed)
    Show all 2 references for ABIN185083

  4. Human Polyclonal UBA2 Primary Antibody for EIA, WB - ABIN783602 : Kamitani, Kito, Nguyen, Fukuda-Kamitani, Yeh: Characterization of a second member of the sentrin family of ubiquitin-like proteins. in The Journal of biological chemistry 1998 (PubMed)
    Show all 2 references for ABIN783602

More Antibodies against SUMO1 Activating Enzyme Subunit 2 Interaction Partners

Human SUMO1 Activating Enzyme Subunit 2 (UBA2) interaction partners

  1. Here, we show that hHR23A utilizes both the UBA2 and XPCB domains to form a stable complex with Vpr, linking Vpr directly to cellular DNA repair pathways and their probable exploitation by the virus.

  2. Data indicate the role of anti-SUMO activating enzyme SAE1 (show SAE1 Antibodies) and SAE2 (show RBBP8 Antibodies) antibody as marker of dermatomyositis.

  3. Data show that the SAE2 (show RBBP8 Antibodies) subunit of the small ubiquitin-like modifier (SUMO (show SUMO1 Antibodies)) E1 is autoSUMOylated at residue Lys (show LYZ Antibodies)-236, and SUMOylation was catalyzed by Ubc9 (show UBE2I Antibodies) at several additional Lys (show LYZ Antibodies) residues surrounding the catalytic Cys (show DNAJC5 Antibodies)-173 of SAE2 (show RBBP8 Antibodies).

  4. loss of SAE1 (show SAE1 Antibodies)/2 activity drives synthetic lethality with Myc (show MYC Antibodies); inactivation of SAE2 (show RBBP8 Antibodies) leads to mitotic catastrophe and cell death upon Myc (show MYC Antibodies) hyperactivation; findings in Myc (show MYC Antibodies)-high breast cancers suggest low tumor SAE1 (show SAE1 Antibodies) and SAE2 (show RBBP8 Antibodies) correlates metastasis-free survival

  5. The mammalian E1 subunits can be imported separately, identify nuclear localization signals (NLSs) in Aos1 (show SAE1 Antibodies) and in Uba2, and demonstrate that their import is mediated by importin alpha (show KPNA4 Antibodies)/beta in vitro and in intact cells.

  6. structures of heterodimeric Sae1 (show SAE1 Antibodies)/Sae2 (show RBBP8 Antibodies)-Mg.ATP and Sae1 (show SAE1 Antibodies)/Sae2 (show RBBP8 Antibodies)-SUMO-1 (show SUMO1 Antibodies)-Mg.ATP complexes

  7. UBA2 stabilizes APOBEC3G by preventing ubiquitin chain elongation and proteasome-mediated proteolysis.

SUMO1 Activating Enzyme Subunit 2 (UBA2) Antigen Profile

Protein Summary

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1\; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 (MIM 613294) and UBA2 form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999

Gene names and symbols associated with UBA2

  • SUMO1 activating enzyme subunit 2 (MICPUN_63834) antibody
  • SUMO1 activating enzyme subunit 2 (MICPUCDRAFT_36729) antibody
  • SUMO-activating enzyme subunit 2 (SAE2) antibody
  • ubiquitin-like modifier activating enzyme 2 (UBA2) antibody
  • ubiquitin-like modifier activating enzyme 2 (Uba2) antibody
  • ubiquitin-like modifier activating enzyme 2 (uba2) antibody
  • AA986091 antibody
  • Arx antibody
  • ATSAE2 antibody
  • EMB2764 antibody
  • EMBRYO DEFECTIVE 2764 antibody
  • F3K23.23 antibody
  • F3K23_23 antibody
  • sae2 antibody
  • sae2-B antibody
  • sae2b antibody
  • SUMO-activating enzyme 2 antibody
  • UBA1 antibody
  • uba2-a antibody
  • uba2-b antibody
  • Ubl1a2 antibody
  • uble1b antibody
  • uble1b-B antibody
  • wu:fi17g06 antibody
  • zgc:66354 antibody

Protein level used designations for UBA2

SUMO1 activating enzyme subunit 2 , SUMO-1 activating enzyme subunit 2 , SUMO-activating enzyme subunit 2 , UBA2, ubiquitin-activating enzyme E1 homolog , anthracycline-associated resistance ARX , ubiquitin-like 1-activating enzyme E1B , Sumo-1 activating enzyme subunit 2 , ubiquitin-like 1 (sentrin) activating enzyme E1B , ubiquitin-like 1 (sentrin) activating enzyme subunit 2 , SUMO-activating enzyme subunit 2-A , SUMO-activating enzyme subunit 2-B , ubiquitin-like 1-activating enzyme E1B-A , ubiquitin-like 1-activating enzyme E1B-B , SUMO1 activating enzyme subunit 2b

GENE ID SPECIES
8248549 Micromonas sp. RCC299
9689179 Micromonas pusilla CCMP1545
816686 Arabidopsis thaliana
10054 Homo sapiens
50995 Mus musculus
308508 Rattus norvegicus
476490 Canis lupus familiaris
399235 Xenopus laevis
406672 Danio rerio
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