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anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) Antibodies

SENP1 encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. Additionally we are shipping SENP1 Proteins (4) and SENP1 Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SENP1 29843 Q9P0U3
SENP1 223870 P59110
SENP1 300193  
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Top anti-SENP1 Antibodies at antibodies-online.com

Showing 10 out of 105 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SENP1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of hSENP1-K578 (ABIN388043) in HL-60, Hela cell line lysates (35 µg/lane). SENP1 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of SENP1 polyclonal antibody (ABIN388042) in whole HL60 cell lysate: SENP1 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Mouse Senp1 Antibody (Center) (ABIN1881788) western blot analysis in mouse Neuro-2a cell line lysates (35 µg/lane). This demonstrates the Mouse Senp1 antibody detected the Mouse Senp1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti-SENP1 antibody IHC staining of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1104176 concentration 10 ug/ml. 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using SENP1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details

SENP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


Top referenced anti-SENP1 Antibodies

  1. Mouse (Murine) Polyclonal SENP1 Primary Antibody for WB - ABIN1881788 : Bawa-Khalfe, Cheng, Lin, Ittmann, Yeh: SENP1 induces prostatic intraepithelial neoplasia through multiple mechanisms. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881788

  2. Human Polyclonal SENP1 Primary Antibody for WB - ABIN388043 : Gong, Millas, Maul, Yeh: Differential regulation of sentrinized proteins by a novel sentrin-specific protease. in The Journal of biological chemistry 2000 (PubMed)
    Show all 3 references for ABIN388043

  3. Human Polyclonal SENP1 Primary Antibody for IHC (p), WB - ABIN388042 : Chen, Chen: MDM2-ARF complex regulates p53 sumoylation. in Oncogene 2003 (PubMed)
    Show all 3 references for ABIN388042

  4. Human Polyclonal SENP1 Primary Antibody for EIA, WB - ABIN356750 : Long, Burke: Interferon production by double-stranded RNA: a comparison of induction by reovirus to that by a synthetic double-stranded polynucleotide. in The Journal of general virology 1971 (PubMed)
    Show all 2 references for ABIN356750

  5. Human Polyclonal SENP1 Primary Antibody for WB - ABIN2786045 : Ohbayashi, Kawakami, Muromoto, Togi, Ikeda, Kamitani, Sekine, Honjoh, Matsuda: The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against SENP1 Interaction Partners

Xenopus laevis SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. XSENP1a and XSENP1b are sumo-specific proteases that inhibit normal head formation by inhibiting Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

Human SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. Genetic interactions of SNPs in CARD14 (show CARD14 Antibodies), SENP1 and VEGFA (show VEGFA Antibodies) might represent a functional mechanism in the pathogenesis of high altitude polycythemia.

  2. SENP1 desensitizes hypoxic ovarian cancer cells to cisplatin by up-regulating HIF-1alpha (show HIF1A Antibodies)

  3. SENP1 expression has strong prognostic impact in a molecularly defined subset of cancers. This is per se not surprising as the biologic impact of each individual molecular event is likely to be dependent on its cellular environment.

  4. SENP1 was expressed in human islets, and its mRNA level was unchanged in islets from donors with T2D. In cultured islets, overexpressed SENP1-GFP colocalized with secretory granules at the plasma membrane

  5. SENP1 uses remote substrate binding for conformational flexibility and activation

  6. SENP1 up-regulation in diseased heart is mediated via calcineurin (show PPP3CA Antibodies)-NFAT (show NFATC1 Antibodies)/MEF2C (show MEF2C Antibodies)-PGC-1alpha (show PPARGC1A Antibodies) pathway.

  7. results provide independent evidence in support of a role for SENP1 in chronic mountain sickness in individuals of Quechua ancestry and suggest the SENP1 and ANP32D (show ANP32D Antibodies) signatures of selection are in tight linkage disequilibrium (LD).

  8. Over-expression of small ubiquitin-like modifier (show SUMO1 Antibodies) proteases 1 predicts chemo-sensitivity and poor survival in non-small cell lung cancer.(

  9. low expression of miR (show MLXIP Antibodies)-145 was correlated with high expression of SENP1 in Prostate cancer cell line and the SENP1 3'-untranslated region was a regulative target of miR (show MLXIP Antibodies)-145 in vitro.

  10. results delineate a key role for Senp1in IL-6 (show IL6 Antibodies) induced proliferation and survival of MM cells, suggesting it may be a potential new therapeutic target in MM

Mouse (Murine) SUMO1/sentrin Specific Peptidase 1 (SENP1) interaction partners

  1. SENP1 deletion in adipocytes causes Type 1 diabetes mellitus via enhanced SUMOylation of NEMO (show IKBKG Antibodies), leading to increased NF-kappaB (show NFKB1 Antibodies) activity, cytokine production and pancreatic inflammation.

  2. results of the present study are of both theoretical and therapeutic significance to explore the potential roles of SENP1 under IH condition and elucidated the mechanisms underlying microglial survival and activation

  3. A role for islet SENP1 as a regulator of in vivo glucose homeostasis was demonstrated by the tissue-selective and inducible knockout of this enzyme.

  4. SENP1 up-regulation in diseased heart is mediated via calcineurin (show PPP3CA Antibodies)-NFAT (show NFATC1 Antibodies)/MEF2C (show MEF2C Antibodies)-PGC-1alpha (show PPARGC1A Antibodies) pathway.

  5. SENP1 deficiency exacerbates ischemia-reperfusion injury in cardiomyocytes via a HIF1alpha (show HIF1A Antibodies)-dependent pathway.

  6. SENP1 enhances adipogenesis through de-SUMOylation of Sharp-1 (show BHLHE41 Antibodies), which then releases Sharp-1 (show BHLHE41 Antibodies) repression of PPARgamma (show PPARG Antibodies) expression and adipocyte differentiation. These results reveal SENP1 as a novel regulator in adipogenesis.

  7. Senp1 Is the Primary Activity for Desumoylation of Sumo1 (show SUMO1 Antibodies)-Modified Proteins.

  8. SENP1 is a specific SUMO protease to regulate SUMOylation status of PGC-1alpha (show PPARGC1A Antibodies).

  9. SENP1 is essential for cell survival during endoplasmic reticulum stress.

  10. SENP1 is essential for the development of early T and B cells.

SENP1 Antigen Profile

Protein Summary

This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SENP1

  • SUMO1/sentrin specific peptidase 1 (SENP1) antibody
  • sentrin/SUMO-specific protease 1 (Senp1) antibody
  • similar to Sentrin-specific protease 1 (Sentrin/SUMO-specific protease SENP1) (SENP1) antibody
  • SUMO1/sentrin specific peptidase 1 (senp1-b) antibody
  • SUMO1/sentrin specific peptidase 1 (senp1) antibody
  • SUMO1/sentrin specific peptidase 1 (Senp1) antibody
  • SUMO1/sentrin specific peptidase 1 (senp1-a) antibody
  • 2310046A20Rik antibody
  • D15Ertd528e antibody
  • E330036L07Rik antibody
  • senp1 antibody
  • senp1a antibody
  • senp1b antibody
  • suPr-2 antibody
  • xsenp1 antibody

Protein level used designations for SENP1

sentrin-specific protease 1 , SUMO1/sentrin specific peptidase 1 , sentrin/SUMO-specific protease 1 , similar to Sentrin-specific protease 1 (Sentrin/SUMO-specific protease SENP1) , sentrin/SUMO-specific protease SENP1 , sentrin specific protease 1b , SUMO1/sentrin specific protease 1 , SUMO-1 protease 2 , SUMO-specific protease U1p1 , sentrin specific protease 1a , Sumo1/sentrin/SMT3 specific peptidase 1

GENE ID SPECIES
477629 Canis lupus familiaris
538091 Bos taurus
100157986 Sus scrofa
426185 Gallus gallus
451862 Pan troglodytes
548976 Xenopus (Silurana) tropicalis
707603 Macaca mulatta
714066 Macaca mulatta
100056855 Equus caballus
100190851 Pongo abelii
100329216 Xenopus laevis
100547302 Meleagris gallopavo
100553998 Anolis carolinensis
29843 Homo sapiens
223870 Mus musculus
398517 Xenopus laevis
300193 Rattus norvegicus
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