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anti-SUMO1/sentrin Specific Peptidase 5 (SENP5) Antibodies

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for numerous biologic processes. Additionally we are shipping SENP5 Proteins (4) and SENP5 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SENP5 320213 Q6NXL6
SENP5 205564 Q96HI0
SENP5 303874  
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Top anti-SENP5 Antibodies at antibodies-online.com

Showing 10 out of 100 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-SENP5 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate Sample Type: 1.Rat Testis cells (200ug) Primary Dilution: 1:1000Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image Submitted by: Andreia CarvalhoIBMC-OBF, Portugal . 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SENP5 Antibody (C-term) (ABIN658321) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the SENP5 antibody detected the SENP5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of SENP5 polyclonal antibody (ABIN388050) in Saos-2 cell lysate. SENP5 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COS7 cells, using SENP5 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using SENP5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Cow Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of SENP5 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of SENP5 expression in PC12 (A), Jurkat (B), NIH3T3 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

SENP5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SENP5 Antibodies

  1. Human Polyclonal SENP5 Primary Antibody for IHC (p), WB - ABIN388050 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN388050

  2. Dog (Canine) Polyclonal SENP5 Primary Antibody for WB - ABIN2786236 : Gong, Yeh: Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. in The Journal of biological chemistry 2006 (PubMed)

  3. Human Polyclonal SENP5 Primary Antibody for WB - ABIN658321 : Yun, Wang, Mukhopadhyay, Backlund, Kolli, Yergey, Wilkinson, Dasso: Nucleolar protein B23/nucleophosmin regulates the vertebrate SUMO pathway through SENP3 and SENP5 proteases. in The Journal of cell biology 2008 (PubMed)

More Antibodies against SENP5 Interaction Partners

Human SUMO1/sentrin Specific Peptidase 5 (SENP5) interaction partners

  1. Mild oxidative stress stabilized the SENP5 protein in the oral squamous cell carcinoma cells, and only the combination of SENP5 silencing and H2O2 application led to mitochondria fragmentation and a significant increase in cell apoptosis.

  2. Low expression of SENP5 is associated with good prognosis among breast cancer patients.

  3. Knockdown of SENP5 resulted in increased levels of SUMO-1 (show SUMO1 Antibodies) and SUMO-2 (show SUMO2 Antibodies)/3, inhibition of cell proliferation, defects in nuclear morphology, and appearance of binucleate cells, revealing an essential role for SENP5 in mitosis and/or cytokinesis.

  4. altered subcellular localization of SENP5 in oral squamous cell carcinoma (OSCC) cells and the correlation between SENP5 expression and the differentiation of OSCC.

  5. Nucleolar protein (show MCRS1 Antibodies) B23/nucleophosmin (show NPM1 Antibodies) regulates the vertebrate SUMO pathway through SENP3 (show ULP1 Antibodies) and SENP5 proteases.

SENP5 Antigen Profile

Protein Summary

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006

Gene names and symbols associated with SENP5

  • SUMO1/sentrin specific peptidase 5 (SENP5) antibody
  • SUMO/sentrin specific peptidase 5 (Senp5) antibody
  • SUMO1/sentrin specific peptidase 5 (Senp5) antibody
  • 6230429P13Rik antibody
  • A730063F07Rik antibody
  • AI851888 antibody
  • BB189556 antibody
  • SMT3IP3 antibody

Protein level used designations for SENP5

SUMO/Smt3-specific isopeptidase 3 , SUMO/sentrin specific protease 5 , sentrin-specific protease 5 , sentrin/SUMO-specific protease SENP5 , SUMO1/sentrin specific protease 5 , Sumo1/sentrin/SMT3 specific peptidase 5

GENE ID SPECIES
100069684 Equus caballus
100526077 Sus scrofa
100298192 Bos taurus
320213 Mus musculus
205564 Homo sapiens
303874 Rattus norvegicus
488033 Canis lupus familiaris
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