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anti-SUMO1/sentrin Specific Protease 6 (SENP6) Antibodies

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. Additionally we are shipping SENP6 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SENP6 215351 Q6P7W0
SENP6 26054 Q9GZR1
SENP6 300860  
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Top anti-SENP6 Antibodies at antibodies-online.com

Showing 10 out of 122 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SENP6 Antibody Titration: 0.2-1 ug/mlPositive Control: 721_B cell lysate Sample Type: 1.Rat Testis cells (200ug) Primary Dilution: 1:1000Secondary Antibody: alkaline phosphatase-conjugated anti-rabbitSecondary Dilution: 1:1000Image Submitted by: Andreia CarvalhoIBMC-OBF, Portugal . 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN334488 (0.5µg/ml) staining of HeLa cell nuclear lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of SENP6 polyclonal antibody (ABIN388052) in HL60 cell lysate. SENP6 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p) 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SENP6 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 3 ug/ml] SENP6 monoclonal antibody (M01), clone 4B7 Western Blot analysis of SENP6 expression in IMR-32 . 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using SENP6 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: Senp6Antibody Dilution: 1.0ug/mlSample Tissue: Mouse Lung 100 μL Log in to see 2 to 3 Days
$289.00
Details

SENP6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus)
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Top referenced anti-SENP6 Antibodies

  1. Human Polyclonal SENP6 Primary Antibody for IHC (p), WB - ABIN388052 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)
    Show all 6 references for ABIN388052

  2. Human Monoclonal SENP6 Primary Antibody for IHC (p), ELISA - ABIN565219 : Dou, Huang, Singh, Carpenter, Yeh: Regulation of DNA repair through deSUMOylation and SUMOylation of replication protein A complex. in Molecular cell 2010 (PubMed)
    Show all 3 references for ABIN565219

  3. Human Polyclonal SENP6 Primary Antibody for EIA, IHC (p) - ABIN356759 : Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ... in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)
    Show all 2 references for ABIN356759

  4. Human Polyclonal SENP6 Primary Antibody for ELISA, WB - ABIN185077 : Kim, Baek, Jeon, Nishimori, Suzuki, Uchida, Shimbara, Saitoh, Tanaka, Chung: A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. in The Journal of biological chemistry 2000 (PubMed)

  5. Human Polyclonal SENP6 Primary Antibody for EIA, WB - ABIN375243 : Choi, Chung, Rho, Lee, Lee, Choi, Seol, Baek, Bang, Chung: Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. in The Journal of biological chemistry 2006 (PubMed)

  6. Human Polyclonal SENP6 Primary Antibody for WB - ABIN2784245 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against SENP6 Interaction Partners

Mouse (Murine) SUMO1/sentrin Specific Protease 6 (SENP6) interaction partners

  1. Negative regulation of TLR inflammatory signaling by the SUMO-deconjugating enzyme SENP6.

Human SUMO1/sentrin Specific Protease 6 (SENP6) interaction partners

  1. our data suggest that SENP6, which is highly expressed in gastric cancer cells, regulates the transcriptional activity and stability of FoxM1 (show FOXM1 Antibodies) through deSUMOylation.

  2. the structure of SENP2 (show SUMO1 Antibodies)-Loop1 in complex with SUMO2 (show SUMO2 Antibodies) was solved at 2.15 A resolution, and reveals the details of an interface exclusive to SENP6/7 and the formation of unique contacts between both proteins

  3. Loop 1 insertion in SENP6 and SENP7 as a platform to discriminate between SUMO1 and SUMO2/3 isoforms in this subclass of the SUMO protease family.

  4. study of substrate specificity of SENP6; it is also capable of cleaving mixed chains of SUMO-1 (show SUMO1 Antibodies) and SUMO-2 (show SUMO2 Antibodies)/3; mutation of catalytic cysteine of results in its accumulation in PML (show PML Antibodies) NBs (show NBN Antibodies); findings indicate SUMO-modified PML (show PML Antibodies) is a substrate of SENP6

  5. Results reveal a novel mechanism whereby the finely balanced activities of SENP6 and RNF4 control vertebrate kinetochore assembly through SUMO-targeted destabilization of inner plate components.

  6. SENP1 (show SENP1 Antibodies) localization is influenced by expression and localization of SUMO-1 (show SUMO1 Antibodies)-conjugated target proteins within the cell.

  7. SUSP1 plays an important role in the control of the transcriptional activity of RXRalpha (show RXRA Antibodies) and thus in the RXRalpha (show RXRA Antibodies)-mediated cellular processes

  8. We have investigated the specificity of SUSP1 using vinyl sulfone inhibitors and model substrates. SUSP1 has a strong paralogue bias toward SUMO2 (show SUMO2 Antibodies)/3 and acts preferentially on substrates containing three or more SUMO2 (show SUMO2 Antibodies)/3 moieties

  9. SENP6 and SENP7 exhibit lower rates for processing pre-SUMO1, pre-SUMO2, or pre-SUMO3 in comparison with SENP2

SENP6 Antigen Profile

Protein Summary

Ubiquitin-like molecules (UBLs), such as SUMO1 (UBL1\; MIM 601912), are structurally related to ubiquitin (MIM 191339) and can be ligated to target proteins in a similar manner as ubiquitin. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 (MIM 602362) to the nuclear pore complex, as well as in stabilization of I-kappa-B-alpha (NFKBIA\; MIM 164008) from degradation by the 26S proteasome. Like ubiquitin, UBLs are synthesized as precursor proteins, with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. Thus, the tail sequences of the UBL precursors need to be removed by UBL-specific proteases, such as SENP6, prior to their conjugation to target proteins (Kim et al., 2000

Gene names and symbols associated with SENP6

  • SUMO1/sentrin specific peptidase 6 (SENP6) antibody
  • SUMO/sentrin specific peptidase 6 (Senp6) antibody
  • SUMO1/sentrin specific peptidase 6 (Senp6) antibody
  • 2810017C20Rik antibody
  • E130319N12Rik antibody
  • mKIAA0797 antibody
  • SSP1 antibody
  • SUSP1 antibody

Protein level used designations for SENP6

SUMO1/sentrin specific peptidase 6 , SUMO1/sentrin specific protease 6 , SUMO-1-specific protease 1 , SUMO/sentrin specific protease 6 , sentrin-specific protease 6 , sentrin/SUMO-specific protease SENP6 , 2810017C20Rik , SUMO/sentrin specific peptidase 6 , Sumo1/sentrin/SMT3 specific peptidase 6

GENE ID SPECIES
462829 Pan troglodytes
215351 Mus musculus
481883 Canis lupus familiaris
26054 Homo sapiens
300860 Rattus norvegicus
Selected quality suppliers for anti-SENP6 (SENP6) Antibodies
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