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SUMO1/sentrin Specific Protease 7 Proteins (SENP7)

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for many cellular processes. Additionally we are shipping SENP7 Antibodies (55) and SENP7 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SENP7 57337 Q9BQF6
SENP7 66315 Q8BUH8
Rat SENP7 SENP7 288167 D3ZF42
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Top SENP7 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 5 Days
$385.00
Details

SENP7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for SUMO1/sentrin Specific Protease 7 (SENP7) Interaction Partners

Human SUMO1/sentrin Specific Protease 7 (SENP7) interaction partners

  1. c-Myc (show MYC Proteins) is targeted to the proteasome for degradation in a SUMOylation-dependent manner, regulated by PIAS1 (show PIAS1 Proteins), SENP7 and RNF4 (show RNF4 Proteins)

  2. deSUMOylation by SENP7 is required to promote a permissive chromatin environment for DNA repair.

  3. differential splicing of the SENP7 regulates either tumor suppression or progression

  4. Loop 1 insertion in SENP6 and SENP7 as a platform to discriminate between SUMO1 and SUMO2/3 isoforms in this subclass of the SUMO protease family.

  5. SENP6 and SENP7 exhibit lower rates for processing pre-SUMO1, pre-SUMO2, or pre-SUMO3 in comparison with SENP2

Mouse (Murine) SUMO1/sentrin Specific Protease 7 (SENP7) interaction partners

  1. Senp7 is transiently activated at early stages of neuronal differentiation.

  2. Depletion of Senp7 delocalizes HP1 alpha (show CBX5 Proteins) from pericentric heterochromatin without affecting H3K9me3 levels.

SENP7 Protein Profile

Protein Summary

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1\; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008

Gene names and symbols associated with SENP7

  • sentrin-specific protease 7-like (LOC507820)
  • SUMO1/sentrin specific peptidase 7 (SENP7)
  • SUMO1/sentrin specific peptidase 7 (Senp7)
  • 2410152H17Rik protein
  • 2810413I22Rik protein
  • 2900036C23Rik protein
  • 6030449K19Rik protein
  • AI790676 protein
  • mKIAA1707 protein
  • SENP7 protein

Protein level used designations for SENP7

SUMO-1-specific protease 2 , SUMO1/sentrin specific peptidase 7 , sentrin-specific protease 7 , sentrin/SUMO-specific protease 7 , sentrin/SUMO-specific protease SENP7 , SUMO1/sentrin specific protease 7 , Sumo1/sentrin/SMT3 specific peptidase 7

GENE ID SPECIES
507820 Bos taurus
57337 Homo sapiens
66315 Mus musculus
288167 Rattus norvegicus
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