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anti-SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) Antibodies

The protein encoded by SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Additionally we are shipping SMARCA2 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMARCA2 6595 P51531
SMARCA2 67155 Q6DIC0
SMARCA2 361745  
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Top anti-SMARCA2 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-SMARCA2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rat Un-conjugated ChIP, ICC, IF, WB SMARCA2 / BRM antibody (mAb) tested by ChIP. Chromatin IP performed using the ChIP-IT® Express Kit (Catalog No. 53008) and HeLa Chromatin (1.5 x 106 cell equivalents per ChIP) using 10 µg of SMARCA2 / BRM antibody or the equivalent amount of rat IgG as a negative control. Real time, quantitative PCR (RT-qPCR) was performed on DNA purified from each of the ChIP reactions using a primer pair specific for the CD44 gene. Data are presented as Fold Enrichment of the ChIP antibody signal versus the negative control IgG using the ddCT method. SMARCA2 / BRM antibody (mAb) tested by Immunofluorescence. Formaldehyde fixed HeLa cells stained with SMARCA2 / BRM antibody at a 0.5 µg/ml dilution. 100 μg Log in to see 1 to 2 Days
$466.67
Details
Chicken Mouse Un-conjugated IF, IP, IHC, WB Western blot analysis of Brm on a HeLa cell lysate (Human cervical epitheloid carcinoma, ATCC CCL-2.2). Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-Brm antibody. Immunofluorescence staining of a rabbit lung section. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Cow Rabbit Un-conjugated WB Western blot analysis of BRM expression in HepG2 (A), HeLa (B), THP1 (C), NIH3T3 (D) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Dog Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, ELISA, WB Detection limit for recombinant GST tagged SMARCA2 is approximately 0.1ng/ml as a capture antibody. Immunofluorescence of monoclonal antibody to SMARCA2 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$522.50
Details

SMARCA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SMARCA2 Antibodies

  1. Chicken Monoclonal SMARCA2 Primary Antibody for IF, IP - ABIN967938 : Muchardt, Yaniv: A human homologue of Saccharomyces cerevisiae SNF2/SWI2 and Drosophila brm genes potentiates transcriptional activation by the glucocorticoid receptor. in The EMBO journal 1993 (PubMed)
    Show all 3 references for ABIN967938

  2. Chicken Polyclonal SMARCA2 Primary Antibody for IHC, WB - ABIN2775822 : Muchardt, Yaniv, Mattei: Assignment of HBRM, the human homolog of S. cerevisiae SNF2/SWI2 and Drosophila brm genes, to chromosome region 9p23-p24, by in situ hybridization. in Mammalian genome : official journal of the International Mammalian Genome Society 1994 (PubMed)

  3. Human Monoclonal SMARCA2 Primary Antibody for ChIP, ICC - ABIN2668505 : Okada, Harada, Saiwai, Nakamura, Ohkawa: Generation of a rat monoclonal antibody specific for Brm. in Hybridoma (2005) 2009 (PubMed)

More Antibodies against SMARCA2 Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) interaction partners

  1. our data suggest that concomitant loss of SMARCA2 and SMARCA4 (show SMARCA4 Antibodies) is another hallmark of small cell carcinoma of the ovary, hypercalcemic type-a finding that offers new opportunities for therapeutic interventions.

  2. this study shows for the first time novel SMARCA4 (show SMARCA4 Antibodies)-deficient and SMARCA2-deficient variants in undifferentiated gastrointestinal tract carcinomas

  3. SMARCA4 (show SMARCA4 Antibodies) loss, either alone or with SMARCA2, is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type, restoration of either SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) ATPase (show DNAH8 Antibodies) can inhibit the growth of SCCOHT cell lines

  4. We report, for the first time, co-inactivation and frequent mutations of SMARCB1 (show SMARCB1 Antibodies), SMARCA2 and PBRM1 (show PBRM1 Antibodies) in MRTs.

  5. The miR (show MLXIP Antibodies)-199a/Brm/EGR1 (show EGR1 Antibodies) axis is a determinant of anchorage-independent growth in epithelial tumor cell lines

  6. Knockout of BRG1 (show SMARCA4 Antibodies) or BRM using CRISPR/Cas9 technology resulted in the loss of viability, consistent with a requirement for both enzymes in triple negative breast cancer cells

  7. BAF (show BANF1 Antibodies) complex gene SMARCA2 is mutated in Coffin-Siris syndrome patients.

  8. Phenotype and genotype in Nicolaides-Baraitser syndrome patients with SMARCA2 mutations

  9. Over-expression of BRM in melanoma cells that harbor oncogenic BRAF (show BRAF Antibodies) promoted changes in cell cycle progression and apoptosis consistent with a tumor suppressive role.

  10. Findings suggest that the BRM promoter double insertion homozygotes may be associated with an increased risk of early-stage UADT cancers independent of smoking status and histology.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) interaction partners

  1. BRM depletion enhances the proportion of cells expressing markers of osteoblast precursors at the expense of cells able to differentiate along the adipocyte lineage.

  2. Data show that knockdown of component of chromatin remodeling complex Brm or Baf170 (show SMARCC2 Antibodies) at different stages promotes reprogramming.

  3. Data reveal stage-specific roles of Brm during skeletal myogenesis, via formation of repressive and activatory SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complexes.

  4. Brm protects from UV-induced hyperplastic growth in both cutaneous and corneal keratinocytes

  5. Data suggest that Brg1 (show SMARCA4 Antibodies) and Brm integrate various proinflammatory cues into cell adhesion molecule (show MCAM Antibodies) transactivation in endothelial injury.

  6. A SMARCA2-containing residual SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complex underlies the oncogenic activity of SMARCA4 (show SMARCA4 Antibodies) mutant cancers.

  7. study identifies NO and HDAC2 (show HDAC2 Antibodies) nitrosylation as part of a signaling pathway that regulates cortical development and the expression of Brm in neurons

  8. The absence of Brm increased skin and ocular photocarcinogenesis in mice.

  9. Brm functionally compensates for Brg1 (show SMARCA4 Antibodies) in vivo and that there are significant changes in the relative importance of BRG1 (show SMARCA4 Antibodies)- and BRM-catalyzed SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complexes during the development of an essential cell lineage.

  10. demonstrate a strong functional association between these polymorphisms and loss of BRM expression. These polymorphisms thus have the potential to identify a sub-population of smokers at greater lung cancer risk

SMARCA2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Gene names and symbols associated with SMARCA2

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2) antibody
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (smarca2) antibody
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2) antibody
  • 2610209L14Rik antibody
  • BAF190 antibody
  • Brahma antibody
  • brm antibody
  • hBRM antibody
  • hSNF2a antibody
  • NCBRS antibody
  • psa-4 antibody
  • SNF2 antibody
  • SNF2alpha antibody
  • Snf2l2 antibody
  • SNF2LA antibody
  • Sth1p antibody
  • SWI2 antibody
  • wu:fa56c07 antibody
  • wu:fi27f11 antibody
  • zgc:66238 antibody

Protein level used designations for SMARCA2

ATP-dependent helicase SMARCA2 , BAF190B , BRG1-associated factor 190B , SNF2-alpha , SNF2/SWI2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 , global transcription activator homologous sequence , probable global transcription activator SNF2L2 , protein brahma homolog , sucrose nonfermenting 2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 , subunit of the SWI/SNF chromatin remodeling complex , phasmid Socket Absent PSA-4

GENE ID SPECIES
6595 Homo sapiens
403380 Xenopus laevis
396040 Gallus gallus
67155 Mus musculus
334032 Danio rerio
476335 Canis lupus familiaris
540904 Bos taurus
361745 Rattus norvegicus
100126853 Sus scrofa
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