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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) ELISA Kits

The protein encoded by SMARCA2 is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Additionally we are shipping SMARCA2 Antibodies (48) and SMARCA2 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SMARCA2 SMARCA2 6595 P51531
Anti-Mouse SMARCA2 SMARCA2 67155 Q6DIC0
Anti-Rat SMARCA2 SMARCA2 361745  
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More ELISA Kits for SMARCA2 Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) interaction partners

  1. our data suggest that concomitant loss of SMARCA2 and SMARCA4 (show SMARCA4 ELISA Kits) is another hallmark of small cell carcinoma of the ovary, hypercalcemic type-a finding that offers new opportunities for therapeutic interventions.

  2. this study shows for the first time novel SMARCA4 (show SMARCA4 ELISA Kits)-deficient and SMARCA2-deficient variants in undifferentiated gastrointestinal tract carcinomas

  3. SMARCA4 (show SMARCA4 ELISA Kits) loss, either alone or with SMARCA2, is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type, restoration of either SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) ATPase (show DNAH8 ELISA Kits) can inhibit the growth of SCCOHT cell lines

  4. We report, for the first time, co-inactivation and frequent mutations of SMARCB1 (show SMARCB1 ELISA Kits), SMARCA2 and PBRM1 (show PBRM1 ELISA Kits) in MRTs.

  5. The miR (show MLXIP ELISA Kits)-199a/Brm/EGR1 (show EGR1 ELISA Kits) axis is a determinant of anchorage-independent growth in epithelial tumor cell lines

  6. Knockout of BRG1 (show SMARCA4 ELISA Kits) or BRM using CRISPR/Cas9 technology resulted in the loss of viability, consistent with a requirement for both enzymes in triple negative breast cancer cells

  7. BAF (show BANF1 ELISA Kits) complex gene SMARCA2 is mutated in Coffin-Siris syndrome patients.

  8. Phenotype and genotype in Nicolaides-Baraitser syndrome patients with SMARCA2 mutations

  9. Over-expression of BRM in melanoma cells that harbor oncogenic BRAF (show BRAF ELISA Kits) promoted changes in cell cycle progression and apoptosis consistent with a tumor suppressive role.

  10. Findings suggest that the BRM promoter double insertion homozygotes may be associated with an increased risk of early-stage UADT cancers independent of smoking status and histology.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 2 (SMARCA2) interaction partners

  1. BRM depletion enhances the proportion of cells expressing markers of osteoblast precursors at the expense of cells able to differentiate along the adipocyte lineage.

  2. Data show that knockdown of component of chromatin remodeling complex Brm or Baf170 (show SMARCC2 ELISA Kits) at different stages promotes reprogramming.

  3. Data reveal stage-specific roles of Brm during skeletal myogenesis, via formation of repressive and activatory SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complexes.

  4. Brm protects from UV-induced hyperplastic growth in both cutaneous and corneal keratinocytes

  5. Data suggest that Brg1 (show SMARCA4 ELISA Kits) and Brm integrate various proinflammatory cues into cell adhesion molecule (show MCAM ELISA Kits) transactivation in endothelial injury.

  6. A SMARCA2-containing residual SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complex underlies the oncogenic activity of SMARCA4 (show SMARCA4 ELISA Kits) mutant cancers.

  7. study identifies NO and HDAC2 (show HDAC2 ELISA Kits) nitrosylation as part of a signaling pathway that regulates cortical development and the expression of Brm in neurons

  8. The absence of Brm increased skin and ocular photocarcinogenesis in mice.

  9. Brm functionally compensates for Brg1 (show SMARCA4 ELISA Kits) in vivo and that there are significant changes in the relative importance of BRG1 (show SMARCA4 ELISA Kits)- and BRM-catalyzed SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complexes during the development of an essential cell lineage.

  10. demonstrate a strong functional association between these polymorphisms and loss of BRM expression. These polymorphisms thus have the potential to identify a sub-population of smokers at greater lung cancer risk

SMARCA2 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Gene names and symbols associated with SMARCA2

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (SMARCA2) antibody
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (smarca2) antibody
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 (Smarca2) antibody
  • 2610209L14Rik antibody
  • BAF190 antibody
  • Brahma antibody
  • brm antibody
  • hBRM antibody
  • hSNF2a antibody
  • NCBRS antibody
  • psa-4 antibody
  • SNF2 antibody
  • SNF2alpha antibody
  • Snf2l2 antibody
  • SNF2LA antibody
  • Sth1p antibody
  • SWI2 antibody
  • wu:fa56c07 antibody
  • wu:fi27f11 antibody
  • zgc:66238 antibody

Protein level used designations for SMARCA2

ATP-dependent helicase SMARCA2 , BAF190B , BRG1-associated factor 190B , SNF2-alpha , SNF2/SWI2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2 , global transcription activator homologous sequence , probable global transcription activator SNF2L2 , protein brahma homolog , sucrose nonfermenting 2-like protein 2 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 , subunit of the SWI/SNF chromatin remodeling complex , phasmid Socket Absent PSA-4

GENE ID SPECIES
6595 Homo sapiens
403380 Xenopus laevis
396040 Gallus gallus
67155 Mus musculus
334032 Danio rerio
476335 Canis lupus familiaris
540904 Bos taurus
361745 Rattus norvegicus
100126853 Sus scrofa
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