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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 Proteins (SMARCA5)

The protein encoded by SMARCA5 is a member of the SWI/SNF family of proteins. Additionally we are shipping SMARCA5 Antibodies (83) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMARCA5 8467 O60264
SMARCA5 93762 Q91ZW3
Rat SMARCA5 SMARCA5 307766  
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Top SMARCA5 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SMARCA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) Interaction Partners

Zebrafish SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) interaction partners

  1. CNBP (show CNBP Proteins) up-regulates tbx2b and smarca5, and down-regulates wnt5b (show WNT5B Proteins) gene expression.

Xenopus laevis SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) interaction partners

  1. The tight coupling of ATP hydrolysis to DNA translocation suggests that DNA translocation is not energetically rate limiting for nucleosome repositioning by ISWI.

  2. results demonstrate that distinctly from its role in spindle assembly, RanGTP maintains spindle microtubules in anaphase through the local activation of ISWI and that this is essential for proper chromosome segregation

  3. Plays a critical role for ISWI chromatin remodeling complexes in neural development, including eye differentiation, in the Xenopus laevis embryo.

  4. present the X-ray structure of Xenopus laevis ISWI SANT domain, derived from limited proteolysis of a C-terminal fragment of ISWI protein

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) interaction partners

  1. The action of SNF2H at CTCF (show CTCF Proteins) sites is functionally important as depletion of CTCF (show CTCF Proteins) or SNF2H affects transcription of a common group of genes.

  2. Knockdown of SMARCA5 expression in MDA-MB-231 and MDA-MB-435s cell lines.

  3. Data show the mechanism of nucleosome sliding by the chromatin remodeling motor SNF2h protein.

  4. CHD3.1 and ACF1 (show BAZ1A Proteins)-SNF2H display counteractive activities but similar histone affinities.

  5. Data show that CCCTC-binding factor (CTCF (show CTCF Proteins)) together with ISWI (show SMARCA1 Proteins) ATPase SMARCA5 and members of the Cohesin complex (show SMC3 Proteins) associate with the SPI1 (show SPI1 Proteins) protein is disrupted in acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) blasts.

  6. SMARCA5 targeting to UV-C damage depends on transcription and histone modifications and requires functional SWI2/SNF2 (show SMARCA2 Proteins)-ATPase and SLIDE domains.

  7. this study finds that the H4 tail promotes ATP-binding pocket closure in SNF2h.

  8. study unveils a functional link between DNA damage-induced poly(ADP-ribosyl)ation, SMARCA5-mediated chromatin remodeling and RNF168 (show RNF168 Proteins)-dependent signaling and repair of DSBs.

  9. Data indicate that the heterochromatic H2A.X is preferentially phosphorylated presumably by the accumulating WSTF-ISWI chromatin remodeling (WICH) complex, and suggests that Tyr142p might have a specific role in heterochromatin.

  10. Introduction of the miR (show MLXIP Proteins)-99 family of miRNAs into cells reduced the rate and overall efficiency of repair by both homologous recombination and non-homologous end joining.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5) interaction partners

  1. Snf2h controls chromatin organization and histone H1 (show H1F0 Proteins) dynamics for the establishment of gene expression programs underlying cerebellar morphogenesis and neural maturation.

  2. The results demonstrated a novel role of CECR2-containing complexes in spermatogenesis and showed that CECR2 interacts predominantly with SNF2H instead of SNF2L (show SMARCA1 Proteins) in the testis.

  3. role for SNF2H in both repression and activation of cytokine genes.

  4. Smarca5 is a key regulator of global chromatin structure.

  5. Smarca5-NoRC complex has a role in heterochromatin formation and silencing of ribosomal gene transcription

  6. Snf2h-/- embryos die during the periimplantation stage. Blastocyst outgrowth experiments indicate that loss of Snf2h results in growth arrest and cell death of both the trophectoderm and inner cell mass.

SMARCA5 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The protein encoded by this gene is a component of the chromatin remodeling and spacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. The encoded protein is similar in sequence to the Drosophila ISWI chromatin remodeling protein.

Gene names and symbols associated with SMARCA5

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (smarca5)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (SMARCA5)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 (Smarca5)
  • 4933427E24Rik protein
  • chunp6878 protein
  • D030040M08Rik protein
  • D330027N15Rik protein
  • fb26d12 protein
  • fb49g04 protein
  • hISWI protein
  • hSNF2H protein
  • im:7146484 protein
  • ISWI protein
  • MGC79455 protein
  • MommeD4 protein
  • SMARCA5 protein
  • Snf2h protein
  • WCRF135 protein
  • wu:fb26d12 protein
  • wu:fb49g04 protein
  • zgc:158434 protein

Protein level used designations for SMARCA5

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 , actin dependent regulator of chromatin A5 , matrix associated , SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 , imitation switch ISWI , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a5 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5 , sucrose nonfermenting protein 2 homolog , sucrose nonfermenting-like 5 , mSnf2h

GENE ID SPECIES
282615 Danio rerio
399165 Xenopus laevis
461517 Pan troglodytes
493355 Xenopus (Silurana) tropicalis
8467 Homo sapiens
93762 Mus musculus
422457 Gallus gallus
475451 Canis lupus familiaris
537503 Bos taurus
307766 Rattus norvegicus
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