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SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 Proteins (SMARCC1)

The protein encoded by SMARCC1 is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Additionally we are shipping SMARCC1 Antibodies (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMARCC1 6599 Q92922
SMARCC1 20588 P97496
Rat SMARCC1 SMARCC1 301020  
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Top SMARCC1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SMARCC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) interaction partners

  1. Results show the secondary structure of SWIRM domain of BAF155 consists of five alpha-helices forming a typical histone fold for DNA interactions.

  2. we identify BAF155 as a substrate for arginine methyltransferase CARM1 (show CARM1 Proteins).

  3. Wwp2 (show WWP2 Proteins) acts as a ubiquitin ligase of SRG3.

  4. miR (show MLXIP Proteins)-320c regulates the resistance of pancreatic cancer cells to gemcitabine through SMARCC1.

  5. loss of BAF155 expression represents another mechanism for inactivation of SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) complex activity in the development in human cancer.

  6. Data show that the mechanism of BAF155-mediated stabilization of BAF57 involves blocking its ubiquitination by preventing interaction with TRIP12.

  7. protein levels of BAF155/170 dictate the maximum cellular amount of BAF57 (show SMARCE1 Proteins)

  8. BAF155 and potentially INI1 (show SMARCB1 Proteins) are substrates for Akt (show AKT1 Proteins) phosphorylation

  9. Constitutive expression of SRG3 inhibits positive selection processes in T-cell receptor transgenic mice.

  10. An increased expression of SMARCC1 protein was found in prostate cancer positively correlated with tumour dedifferentiation, progression, metastasis and time to recurrence.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1) interaction partners

  1. the role of BAF155 in late pre-implantation stages of mouse embryos

  2. Specific inactivation of Srg3 a core subunit of the remodeling complex, in developing limb buds hampered the transcriptional upregulation of Shh (show SHH Proteins)/Gli (show GLI1 Proteins) target genes, including the Shh (show SHH Proteins) receptor Ptch1 (show PTCH1 Proteins) and its downstream effector Gli1 (show GLI1 Proteins) in the posterior limb bud

  3. the increased frequency of Treg cells in the spinal cord of beta-actin (show ACTB Proteins)-SRG3 Tg mice might induce the suppression of and accelerate the recovery from EAE symptoms.

  4. Deletion of either Brg1 (show SMARCA4 Proteins) in the subependymal zone (SEZ) causes the progeny of adult neural stem cells to convert to the ependymal lineage within the SEZ while migrating neuroblasts convert to different glial lineages en route to or in the olfactory bulb.

  5. Characterization of a missense mutation allele of the Smarcc1 gene (Smarcc1msp3 or Baf155msp3); lends new insight into the functions of the BAF (show BANF1 Proteins) chromatin remodeling complex during the critical stage of neural tube closure

  6. we identify BAF155 as a substrate for arginine methyltransferase CARM1 (show CARM1 Proteins).

  7. Wwp2 (show WWP2 Proteins) acts as a ubiquitin ligase (show RNF123 Proteins) of SRG3.

  8. Liver progenitor cells have intrinsic, cell proliferation-independent characteristics resulting in an increased reprogramming capacity compared to differentiated liver cells which requires the BAF (show BANF1 Proteins) complex.

  9. CHFR interacts with BRG1, SNF5, and BAF60a of the SWI/SNF-like BAF complex and ubiquitinates them to target for degradation through a proteasome-mediated pathway; SRG3 stabilizes these components by blocking their interaction with CHFR.

  10. Our results establish a novel function of Srg3 in tumor suppression

SMARCC1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

Gene names and symbols associated with SMARCC1

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (smarcc1)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a (smarcc1a)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (SMARCC1)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 (Smarcc1)
  • AI115498 protein
  • BAF155 protein
  • CRACC1 protein
  • MGC53976 protein
  • Rsc8 protein
  • smarcc1 protein
  • SRG3 protein
  • SWI3 protein

Protein level used designations for SMARCC1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 , BRG1-associated factor 155 , SWI/SNF complex 155 kDa subunit , SWI/SNF complex subunit SMARCC1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 , chromatin remodeling complex BAF155 subunit , mammalian chromatin remodeling complex BRG1-associated factor 155 , SWI3-related protein

GENE ID SPECIES
380024 Xenopus laevis
403020 Danio rerio
6599 Homo sapiens
476640 Canis lupus familiaris
20588 Mus musculus
301020 Rattus norvegicus
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