You are viewing an incomplete version of our website. Please click to reload the website as full version.

SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 Proteins (SMARCE1)

The protein encoded by SMARCE1 is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. Additionally we are shipping SMARCE1 Antibodies (82) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SMARCE1 6605 Q969G3
SMARCE1 57376 O54941
Rat SMARCE1 SMARCE1 303518  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SMARCE1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

SMARCE1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1) Interaction Partners

Human SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1) interaction partners

  1. a family with a pediatric CCM patient and an adult CCM patient and several asymptomatic relatives carrying a germline SMARCE1 mutation.

  2. Addition of the EGFR (show EGFR Proteins) inhibitor gefitinib restores the sensitivity of SMARCE1-knockdown cells to MET and ALK inhibitors in NSCLCs. Our findings link SMARCE1 to EGFR (show EGFR Proteins) oncogenic signaling and suggest targeted treatment options for SMARCE1-deficient tumors.

  3. The results suggested that BAF57 is involved in ovarian cancer cell growth and sensitivity to anticancer agents, and that BAF57 may be a target for ovarian cancer therapy.

  4. BAF (show BANF1 Proteins) complex gene SMARCE1 is mutated in Coffin-Siris syndrome patients.

  5. Genotype-phenotype correlation of Coffin-Siris syndrome caused by mutations in SmarCE1 gene.

  6. Since both TTF1 (show NKX2-1 Proteins) and SMARCE1 are involved in chromatin remodeling, our results imply an epigenetic regulatory mechanism for T-cell recruitment that invites deciphering.

  7. these results demonstrate that loss of SMARCE1 is relevant to cranial as well as spinal meningiomas

  8. Data indicate that BAF57 deregulation predisposes to metastasis.

  9. Our findings identify multiple-spinal-meningioma disease as a new discrete entity and establish a key role for the SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) complex in the pathogenesis of both meningiomas and tumors with clear-cell histology.

  10. mutations in BAF57 could impinge on several oncogenic signaling pathways contributing to the origin and/or development of breast cancer.

Mouse (Murine) SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily E, Member 1 (SMARCE1) interaction partners

  1. The N terminus of Brdt (show BRDT Proteins) is involved in the recognition of Smarce1 as well as in the reorganization of hyperacetylated round spermatid chromatin.

  2. suggest a novel mechanism for transcriptional repression by TSHZ3 (show ZNF537 Proteins) in which TSHZ3 (show ZNF537 Proteins) and BAF57 cooperate to modulate MyoD (show MYOD1 Proteins) activity on the Myog (show MYOG Proteins) promoter to regulate skeletal muscle differentiation.

  3. Data show that neuregulin-1 (show NRG1 Proteins) (NRG) inhibition is followed by a decrease in NSC proliferation and of neuronal or oligodendroglial differentiation, and that Nrg-1 (show NRG1 Proteins) physically interacts with BRM (show SMARCA2 Proteins) and BAF57.

  4. Reciprocal regulation of CD4 (show CD4 Proteins)/CD8 (show CD8A Proteins) expression by SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins)-like BAF (show BANF1 Proteins) complexes.

  5. The ER interacts with BAF57, which is stimulated by estrogen and requires both a functional hormone-binding domain & the DNA-binding region of the ER. The p160 (show MSH6 Proteins) family of coactivators interacts with BAF57. Their potentiation of transcription depends on it.

  6. Smarce1 (Baf27)is a critical modulator of the androgen neceptor (AR) that is capable of altering AR activity, coactivator function, and AR-dependent proliferation.

  7. BAF (show BANF1 Proteins) complex uses BAF57 to remodel the endogenous, H1-containing chromatin at the CD4 (show CD4 Proteins) silencer, which facilitates the binding of Runx1 (show RUNX1 Proteins), a key repressor of CD4 (show CD4 Proteins) transcription.

SMARCE1 Protein Profile

Protein Summary

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Gene names and symbols associated with SMARCE1

  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (smarce1)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (SMARCE1)
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (Smarce1)
  • 2810417B20Rik protein
  • 5830412H02Rik protein
  • 9030408N19Rik protein
  • Baf27 protein
  • Baf57 protein
  • DKFZp459O2235 protein
  • fb54d11 protein
  • MGC52696 protein
  • MGC69429 protein
  • MGC81726 protein
  • RGD1304726 protein
  • SMARCE1 protein
  • wu:fb33d02 protein
  • wu:fb54d11 protein
  • XBaf57 protein

Protein level used designations for SMARCE1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 , BRG1-associated factor 57 , SWI/SNF-related matrix-associated actin-dependent regulator of chromatin e1 , chromatin remodeling complex BRG1-associated factor 57 , fb33d02 , BAF57 , SWI/SNF-related matrix-associated actin-dependent regulator chromatin subfamily E member 1

GENE ID SPECIES
448018 Xenopus (Silurana) tropicalis
100174285 Pongo abelii
6605 Homo sapiens
322248 Danio rerio
379061 Xenopus laevis
420047 Gallus gallus
608250 Canis lupus familiaris
540910 Bos taurus
57376 Mus musculus
303518 Rattus norvegicus
Selected quality suppliers for SMARCE1 Proteins (SMARCE1)
Did you look for something else?