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anti-Sad1 and UNC84 Domain Containing 1 (SUN1) Antibodies

SUN1 is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. Additionally we are shipping SUN1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SUN1 23353 O94901
SUN1 77053 Q9D666
SUN1 360773  
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Top anti-SUN1 Antibodies at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated IHC, WB WB Suggested Anti-UNC84A Antibody Titration: 0.2-1 ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IP, WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Mouse Un-conjugated WB Western Blot analysis of UNC84A expression in transfected 293T cell line by UNC84A MaxPab polyclonal antibody.Lane 1: UNC84A transfected lysate(28.38 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to UNC84A on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB UNC84A antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (54.01 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$449.17
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated ELISA, WB   200 μg Log in to see 8 to 10 Days
$537.17
Details

SUN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
,
,

Mouse (Murine)


Rat (Rattus)


Top referenced anti-SUN1 Antibodies

  1. Dog (Canine) Polyclonal SUN1 Primary Antibody for IHC, WB - ABIN2783971 : Chi, Haller, Peloponese, Jeang: Histone acetyltransferase hALP and nuclear membrane protein hsSUN1 function in de-condensation of mitotic chromosomes. in The Journal of biological chemistry 2007 (PubMed)

  2. Human Polyclonal SUN1 Primary Antibody for WB - ABIN525108 : Jung, Nobumori, Goulbourne, Tu, Lee, Tatar, Wu, Yoshinaga, de Jong, Coffinier, Fong, Young: Farnesylation of lamin B1 is important for retention of nuclear chromatin during neuronal migration. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  3. Human SUN1 Primary Antibody for ICC, IF - ABIN1042680 : Hodzic, Yeater, Bengtsson, Otto, Stahl: Sun2 is a novel mammalian inner nuclear membrane protein. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against SUN1 Interaction Partners

Caenorhabditis elegans (C. elegans) Sad1 and UNC84 Domain Containing 1 (SUN1) interaction partners

  1. POT-1 (show POT1 Antibodies) has a role in anchoring telomeres through SUN-1 at the nuclear periphery.

  2. This suggests that SUN-1 phosphorylation is critical to delaying meiosis in response to perturbed synapsis. SUN-1 may be an integral part of a checkpoint system to monitor establishment of the obligate crossover

  3. The dynamics of matefin/SUN-1 aggregates remained unchanged throughout leptonene/zygotene, despite the progression of pairing.

  4. Data show that ZYG-12 is immobile at the outer nuclear membrane and that SUN-1 is sufficient to localize ZYG-12 in cells.

  5. Data suggest that the properties of the nuclear envelope are altered during the time window when homologs are sorted and Matefin/SUN-1 aggregates form, thereby controling the movement, homologous pairing and interhomolog recombination of chromosomes.

Human Sad1 and UNC84 Domain Containing 1 (SUN1) interaction partners

  1. Nuclear envelope associated endosome-mediated transfer depends on the nuclear envelope proteins SUN1 and SUN2 (show SUN2 Antibodies), as well as the Sec61 (show SEC61A1 Antibodies) translocon complex.

  2. SUN1 plays a role in hnRNP (show HNRNPC Antibodies)-involved mRNA export.

  3. An important role for SUN1 and SUN2 (show SUN2 Antibodies) in muscle disease pathogenesis.

  4. these data support a model whereby mitotic phosphorylation of SUN1 disrupts interactions with nucleoplasmic binding partners, promoting disassembly of the nuclear lamina and, potentially, its chromatin interactions

  5. The Caenorhabditis elegans lamin, LMN-1, is required for nuclear migration and interacts with the nucleoplasmic domain of the SUN protein UNC-84.

  6. Results highlight the interactions at the nuclear envelope where mutations in the EMD (show EMD Antibodies) and TMPO (show TMPO Antibodies) gene in combination with mutations in SUN1 have an impact on several components of the network.

  7. Farnesylation of progerin enhances its interaction with SUN1 and reduces SUN1 mobility.

  8. Codepletion of SUN1/2 slows cell proliferation and results in an accumulation of morphologically defective and disoriented mitotic spindles.

  9. Reduction of SUN1 overaccumulation in LMNA mutant fibroblasts and in cells derived from (show LMNA Antibodies) HGPS patients corrected nuclear defects and cellular senescence.

  10. These results demonstrate that the interplay between SUN1 and farnesylated prelamin A contributes to nuclear positioning in human myofibers and may be implicated in pathogenetic mechanisms.

Mouse (Murine) Sad1 and UNC84 Domain Containing 1 (SUN1) interaction partners

  1. A cell-type-specific role for Sun1 and Sun2 (show SUN2 Antibodies) in nucleokinesis during cerebellar development, is reported.

  2. ablation of the kinase CDK2 alters the nuclear envelope in mouse spermatocytes, and that the proteins SUN1, KASH5 (also known as CCDC155) and lamin C2 show an abnormal cap-like distribution facing the centrosome.

  3. our results clearly indicate that SUN1 and SUN2 (show SUN2 Antibodies), at least partially, fulfill redundant meiotic functions

  4. Sun1, a component of LINC complexes, but not A-type lamins, which interact with LINC complexes at the nuclear envelope, participate in cone nuclei positioning.

  5. Sun1 has a role in DNA damage response.

  6. It was shown KASH5 possesses hitherto unknown KASH-related sequences that directly interacted with SUN1 and mediated telomere localization. KASH5 interacted with the microtubule-associated dynein- dynactin (show DCTN1 Antibodies) complex.

  7. These findings implicate Sun1 protein accumulation as a common pathogenic event in Lmna (show LMNA Antibodies)(-/-), LmnaDelta9 mice, models for Emery-Dreifuss muscular dystrophy and Hutchinson-Gilford progeria disorders.

  8. Syne-2 (show SYNE2 Antibodies), SUN1 and SUN2 (show SUN2 Antibodies) play critical roles during interkinetic nuclear migration and photoreceptor cell migration in the mouse retina development.

  9. perturbations in lamin A (show LMNA Antibodies)-SUN1 and SUN2 (show SUN2 Antibodies) protein interactions may underlie the opposing effects of EDMD (show EMD Antibodies) and HGPS (show LMNA Antibodies) mutations on nuclear and cellular mechanics

  10. The Sun1 serves as a 'structural bridge' connecting the nuclear interior with the actin cytoskeleton.

SUN1 Antigen Profile

Protein Summary

This gene is a member of the unc-84 homolog family and encodes a nuclear nuclear envelope protein with an Unc84 (SUN) domain. The protein is involved in nuclear anchorage and migration. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with SUN1

  • Protein SUN-1 (sun-1) antibody
  • Sad1 and UNC84 domain containing 1 (SUN1) antibody
  • Sad1 and UNC84 domain containing 1 (Sun1) antibody
  • 4632417G13Rik antibody
  • 5730434D03Rik antibody
  • mKIAA0810 antibody
  • Unc84a antibody

Protein level used designations for SUN1

SUN domain-containing protein 1 , Sad1 unc-84 domain protein 1 , protein unc-84 homolog A , sad1/unc-84 protein-like 1 , unc-84 homolog A

GENE ID SPECIES
179802 Caenorhabditis elegans
23353 Homo sapiens
480806 Canis lupus familiaris
77053 Mus musculus
360773 Rattus norvegicus
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