You are viewing an incomplete version of our website. Please click to reload the website as full version.

Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) ELISA Kits

SGCA encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Additionally we are shipping SGCA Antibodies (40) and SGCA Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SGCA SGCA 6442 Q16586
Anti-Mouse SGCA SGCA 20391 P82350
Anti-Rat SGCA SGCA 303468  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top SGCA ELISA Kits at antibodies-online.com

Showing 1 out of 1 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
Details

More ELISA Kits for SGCA Interaction Partners

Human Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) interaction partners

  1. Results show that HRD1 (show SYVN1 ELISA Kits) and RFP2 (show TRIM13 ELISA Kits) contributes are required for the disposal of V247M alpha-sarcoglycan mutant.

  2. 2 members of a Spanish family with muscular dystrophy had a new missense mutation c409G>A, p.Glu137Lys in exon 5 of the alpha-sarcoglycan gene, as well as a paternal c739G>A, p.Val24Met mutation inexon 6.

  3. DNA analysis demonstrated homozygosity for a point mutation (574C>T) in the alpha-sarcoglycan gene.

  4. E-cadherin (show CDH1 ELISA Kits),alpha-dystroglycan and beta-dystroglycan levels were decreased in the oesophageal primary tumour samples, despite the presence of normal levels of dystroglycan (show DAG1 ELISA Kits) mRNA.

  5. This study reported recessive founder LGMD2D for the Magdalen Islands, an archipelago (show FBXW7 ELISA Kits) settled in the XIXth century, largely by Acadian immigrants.

  6. Peptide sequences in alpha-DG are substrates for protein-O-mannose N-acetylglucosaminyltransferase (show GCNT2 ELISA Kits) 1 (POMGnT1 (show POMGNT1 ELISA Kits)), demonstrated when a library of mannopeptides is generated which corresponds to sequences of the mucin (show SLC13A2 ELISA Kits)-like stem region of alpha-DG.

  7. Long-term, sustainable gene expression of alpha-sarcoglycan was observed following gene transfer mediated by AAV.

  8. Absence of members of the dystrophin (show DMD ELISA Kits)-associated glycoprotein complex constitutes a permissive environment for spontaneous development of embryonal rhabdomyosarcoma associated with mutation of p53 (show TP53 ELISA Kits) and mutation or altered splicing of Mdm2 (show MDM2 ELISA Kits).

  9. Two adult brothers with a mild form of LGMD2D, compound heterozygous for two missense mutations of the SGCA gene (Arg77Cys, Val247Met), presented with respiratory insufficiency while they were still ambulatory.

  10. Biglycan (show BGN ELISA Kits) is a ligand for two members of the sarcoglycan (show SGCD ELISA Kits) complex and regulates their expression at discrete developmental ages.

Mouse (Murine) Sarcoglycan, alpha (50kDa Dystrophin-Associated Glycoprotein) (SGCA) interaction partners

  1. The differential expression of two alpha-SG mRNAs during mouse embryonic development may be a consequence of the differential regulation of both promoters by myogenic and cardiogenic factors.

  2. Loss of sarcoglycan (show SGCD ELISA Kits) is associated with loss of miRNA669a and myopathy.

  3. Sgca-;Sgce (show SGCE ELISA Kits)-null mouse shows a complete loss of residual sarcoglycans and a strong reduction in both dystrophin (show DMD ELISA Kits) and dystroglycan (show DAG1 ELISA Kits).

  4. Impaired proliferation of Sgca-null myogenic precursors was confirmed by single fiber analysis and this difference correlated with Sgca expression during myogenic progenitor cell proliferation.

  5. Absence of members of the dystrophin (show DMD ELISA Kits)-associated glycoprotein complex constitutes a permissive environment for spontaneous development of embryonal rhabdomyosarcoma associated with mutation of p53 (show TP53 ELISA Kits) and mutation or altered splicing of Mdm2 (show MDM2 ELISA Kits).

  6. These findings suggest that the sarcoglycan (show SGCD ELISA Kits) complex serves a mechanical function in the diaphragm by contributing to muscle passive stiffness and to the modulation of the contractile properties of the muscle.

  7. Muscle masses were 40-100% larger for Sgca-null compared with age- and gender-matched wild-type mice, with the majority of the increased muscle mass for Sgca-null mice attributable to greater connective tissue and water contents

  8. Diaphragm from Sgca-null mouse presents a clear dystrophic phenotype, with necrosis, regeneration, fibre hypertrophy and splitting, excess of collagen and fatty infiltration.

  9. Deficiency of Sgca differently affects fast- and slow-twitch skeletal muscles.

  10. The alpha-SG promoter is activated by MyoD (show MYOD1 ELISA Kits), which interacts with TFIID (show TBP ELISA Kits) and TFIIB (show GTF2B ELISA Kits) in a protein complex differentially located at the distal promoter and around the proximal promoter during myogenic cell differentiation.

SGCA Antigen Profile

Antigen Summary

This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SGCA

  • 50-kda dystrophin-associated glycoprotein (DAG2) antibody
  • sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA) antibody
  • sarcoglycan, alpha (dystrophin-associated glycoprotein) (Sgca) antibody
  • 50-DAG antibody
  • 50DAG antibody
  • A2 antibody
  • adhalin antibody
  • ADL antibody
  • Asg antibody
  • DAG2 antibody
  • DMDA2 antibody
  • LGMD2D antibody
  • SCARMD1 antibody
  • Sgca antibody

Protein level used designations for SGCA

50 kDa dystrophin-associated glycoprotein , 50DAG , adhalin , alpha-SG , alpha-sarcoglycan , dystroglycan-2 , 50kD DAG , sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)

GENE ID SPECIES
100009178 Oryctolagus cuniculus
6442 Homo sapiens
20391 Mus musculus
303468 Rattus norvegicus
Selected quality suppliers for SGCA (SGCA) ELISA Kits
Did you look for something else?