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Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Proteins (SGCB)

SGCB encodes a member of the sarcoglycan family. Additionally we are shipping Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Antibodies (56) and Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SGCB SGCB 497757  
SGCB 6443 Q16585
SGCB 24051 P82349
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Top Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,581.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,585.00
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$2,585.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SGCB Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
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More Proteins for Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Interaction Partners

Fruit Fly (Drosophila melanogaster) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. subcellular localization of dScgbeta dramatically changes during mitosis through possible association with tubulin (show TUBB Proteins); these observations point to a complex role of sarcoglycans in non-muscle tissues.

Human Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. Clinical severity of limb-girdle muscular dystrophy type 2Emay be predicted by SGCB gene mutation and sarcoglycan (show SGCD Proteins) protein expression.

  2. Defective assembly of sarcoglycan (show SGCD Proteins) complex in patients with beta-sarcoglycan gene mutations

  3. beta-sarcoglycan and SPATA18 (show SPATA18 Proteins) may have a role in limb-girdle muscular dystrophy type 2E

  4. While the quantity of beta-sarcoglycan was nearly normal in the limb girdle muscular dystrophy (LGMD)2E carrier, the levels of dysferlin protein were reduced to 50% of controls in the carriers of LGMD2B.

  5. These data suggest that formation of the beta-delta-core may promote the export and deposition of sarcoglycan (show SGCD Proteins) subcomplexes at the plasma membrane, and therefore identifies a mechanism for sarcoglycan (show SGCD Proteins) transport.

  6. The limb-girdle muscular dystrophy patients with beta-sarcoglycan deficient LGMD2E do not enable an accurate prediction of the genotype.

Mouse (Murine) Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) interaction partners

  1. serglycin (show SRGN Proteins) deficient mice exhibited elevated concentrations of serum LDL after feeding high-fat diet for 20 weeks.

  2. serglycin (show SRGN Proteins) plays a critical role in the maturation of dense-core cytotoxic granules in cytotoxic lymphocytes and the trafficking and storage of perforin (show PRF1 Proteins) and granzyme B, whereas granzyme A (show GZMA Proteins) is unaffected

  3. In Sgcb-null mice, severe morphological disruption was present from 4 weeks in both quadriceps and diaphragm, and included conspicuous deposition of extracellular matrix components.

  4. Wild-type mast cells efficiently degraded exogenous or endogenously produced IL-13 (show IL13 Proteins) upon degranulation,whereas serglycin (show SRGN Proteins) -/- mast cells completely lacked this ability.

  5. Dopamine storage increased during mast cell maturation from bone marrow precursors, and was dependent on the presence of serglycin (show SRGN Proteins).

  6. Cells lacking mouse mast cell protease 6 exhibited similar defects in apoptosis as observed in serglycin (show SRGN Proteins)(-/-) cells, indicating that the pro-apoptotic function of serglycin (show SRGN Proteins) is due to downstream effects of proteases that are complex-bound to serglycin (show SRGN Proteins)

  7. The PRG-1 (show PTGR1 Proteins) transcription is initiated at multiple transcription start site and no influence on expression in vivo by Nex1 (show NEUROD6 Proteins) deficiency.

  8. Aging leads to changes in expression of beta-sarcoglycan in aged affected muscles (diaphragm and limb).

  9. serglycin proteoglycan (show SRGN Proteins) as a novel player in mast cell apoptosis.

  10. serglycin proteoglycan (show SRGN Proteins) is dispensable for normal secretion and activity of mast cell proteases in response to peritoneal infection with T. gondii.

Sarcoglycan, beta (43kDa Dystrophin-Associated Glycoprotein) (SGCB) Protein Profile

Protein Summary

This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.

Gene names and symbols associated with SGCB

  • Sarcoglycan beta (Scgbeta)
  • SarcoGlycaN (sgn-1)
  • beta-sarcoglycan (AaeL_AAEL006051)
  • beta-sarcoglycan (CpipJ_CPIJ006944)
  • guanylate cyclase 1, soluble, alpha 3 (Gucy1a3)
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (sgcb)
  • sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) (SGCB)
  • sarcoglycan, beta (dystrophin-associated glycoprotein) (Sgcb)
  • serglycin (Srgn)
  • 43kDa protein
  • A3b protein
  • AI747103 protein
  • AI844814 protein
  • beta-sarcoglycan protein
  • beta-SG protein
  • CG5657 protein
  • Dmel\\CG5657 protein
  • DmSCG-beta protein
  • dscgbeta protein
  • Gucy1a1 protein
  • LGMD2E protein
  • Prg protein
  • Prg1 protein
  • scg-beta protein
  • Sgc protein

Protein level used designations for SGCB

sarcoglycan beta , CG5657-PA , Scgbeta-PA , beta-sarcolgycan , beta-sarcoglycan , SarcoGlycaN family member (sgn-1) , GCS-alpha-1 , GCS-alpha-3 , Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase) , Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase) , guanylate cyclase soluble subunit alpha-3 , soluble guanylate cyclase large subunit , 43 kDa dystrophin-associated glycoprotein , 43DAG , beta-SG , beta-sarcoglycan(43kD dystrophin-associated glycoprotein) , limb girdle muscular dystrophy 2E (non-linked families) , sarcoglycan, beta (43kD dystrophin-associated glycoprotein) , gp600 , mastocytoma proteoglycan core protein , proteoglycan 1, secretory granule , proteoglycan, secretory granule , secretory granule proteoglycan core protein

GENE ID SPECIES
41525 Drosophila melanogaster
184162 Caenorhabditis elegans
5567384 Aedes aegypti
6039376 Culex quinquefasciatus
497757 Rattus norvegicus
100127262 Xenopus laevis
422760 Gallus gallus
6443 Homo sapiens
100135674 Sus scrofa
535372 Bos taurus
100009208 Oryctolagus cuniculus
100172796 Pongo abelii
24051 Mus musculus
680229 Rattus norvegicus
19073 Mus musculus
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