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Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) ELISA Kits

SGCG encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. Additionally we are shipping Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Antibodies (39) and Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteins (10) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SGCG SGCG 6445 Q13326
Anti-Mouse SGCG SGCG 24053 P82348
Anti-Rat SGCG SGCG 305941  
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More ELISA Kits for Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Interaction Partners

Human Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) interaction partners

  1. These results position archvillin (show SVIL ELISA Kits) as a mechanically sensitive component of the dystrophin (show DMD ELISA Kits) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  2. A report of two siblings with severe childhood onset limb-girdle muscular dystrophy type 2C supports the theory that the mutation G787A in the SGCG gene is a founder mutation.

  3. Molecular epidemiologic methods were used to calculate the frequency of heterozygotes for this SGCG mutation in Moroccan newborns and to estimate the prevalence of LGMD2C in the Moroccan population.

  4. Data suggest that an SNP in an intron of SGCG (rs9552911) is associated with type 2 diabetes [Genome-Wide Association Study in Sikh populations in India & Meta-Analysis]

  5. The C allele of the c.-94C>G polymorphism in delta-sarcoglycan (show SGCD ELISA Kits) is a risk factor for HCM, which is increased by the Amerindian component and can play an important role in the etiology and progression of disease in Mexican patients

  6. four Greek Gypsy patients with limb girdle muscular dystrophy type 2C carried the same homozygous C283Y mutation in the gamma-sarcoglycan gene

  7. The relative incidence of LGMD2C among Japanese Duchenne muscular dystrophy (show DMD ELISA Kits)-like patients can be calculated as 1 in 161 patients suspected to have Duchenne muscular dystrophy (show DMD ELISA Kits).

  8. Clinical, histologic, and immunohistochemical characteristics of three children with limb-girdle muscular dystrophy type 2C. Two novel mutations in the gamma-sarcoglycan gene were present. We found phenotypic differences in two brothers.

  9. Biglycan (show BGN ELISA Kits) is a ligand for two members of the sarcoglycan (show SGCD ELISA Kits) complex and regulates their expression at discrete developmental ages.

  10. The limb-girdle muscular dystrophy patients with gamma-sarcoglycan deficient LGMD2C do not enable an accurate prediction of the genotype.

Mouse (Murine) Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) interaction partners

  1. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx (show DMD ELISA Kits) mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size.

  2. These results position archvillin (show SVIL ELISA Kits) as a mechanically sensitive component of the dystrophin (show DMD ELISA Kits) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  3. This study supports a model where dystrophin (show DMD ELISA Kits), but not the sarcoglycans, protects the cardiac myocyte against mechanical damage.

  4. localization of gamma-SG does not require Tyr (show TYR ELISA Kits)(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation

  5. The limb, shoulder, and pelvic muscles of the gsg-/- mice exhibited progressive muscle hypertrophy and weakness with age, and the findings were similar to those seen in other mouse models for limb-girdle and Duchenne muscular dystrophy (show DMD ELISA Kits).

  6. In sarcoglycan (show SGCD ELISA Kits) mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation.

  7. delta- and gamma-sarcoglycan prevent vascular spasm in coronary arteries and in vascular smooth muscle

  8. sarcoglycan (show SGCD ELISA Kits) and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction

  9. Sarcoglycan gamma missense mutations affect sarcoglycan (show SGCD ELISA Kits) complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan (show SGCD ELISA Kits) mutations in muscular dystrophies.

Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Antigen Profile

Antigen Summary

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Gene names and symbols associated with SGCG

  • sarcoglycan, gamma (sgcg) antibody
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG) antibody
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (Sgcg) antibody
  • sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg) antibody
  • 35DAG antibody
  • 35kDa antibody
  • 5430420E18Rik antibody
  • A4 antibody
  • AI642964 antibody
  • DAGA4 antibody
  • DMDA antibody
  • DMDA1 antibody
  • gamma-SG antibody
  • LGMD2C antibody
  • MAM antibody
  • SCARMD2 antibody
  • SCG3 antibody
  • TYPE antibody
  • zgc:100924 antibody

Protein level used designations for SGCG

gamma-sarcoglycan , 35 kDa dystrophin-associated glycoprotein , 35DAG , 35kD dystrophin-associated glycoprotein , gamma sarcoglycan , gamma-SG , sgcg gene for gamma-sarcoglycan , sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)

GENE ID SPECIES
445292 Danio rerio
6445 Homo sapiens
486043 Canis lupus familiaris
100272144 Sus scrofa
506155 Bos taurus
100009214 Oryctolagus cuniculus
101825067 Mesocricetus auratus
24053 Mus musculus
305941 Rattus norvegicus
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