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Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteins (SGCG)

SGCG encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. Additionally we are shipping Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Antibodies (39) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SGCG 6445 Q13326
SGCG 24053 P82348
Rat SGCG SGCG 305941  
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Top Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
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HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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Yeast Mesocricetus auratus His tag   1 mg Log in to see 56 to 66 Days
$2,588.67
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Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,588.67
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Yeast Dog His tag   1 mg Log in to see 56 to 66 Days
$2,588.67
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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SGCG Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
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More Proteins for Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Interaction Partners

Human Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) interaction partners

  1. These results position archvillin (show SVIL Proteins) as a mechanically sensitive component of the dystrophin (show DMD Proteins) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  2. A report of two siblings with severe childhood onset limb-girdle muscular dystrophy type 2C supports the theory that the mutation G787A in the SGCG gene is a founder mutation.

  3. Molecular epidemiologic methods were used to calculate the frequency of heterozygotes for this SGCG mutation in Moroccan newborns and to estimate the prevalence of LGMD2C in the Moroccan population.

  4. Data suggest that an SNP in an intron of SGCG (rs9552911) is associated with type 2 diabetes [Genome-Wide Association Study in Sikh populations in India & Meta-Analysis]

  5. The C allele of the c.-94C>G polymorphism in delta-sarcoglycan (show SGCD Proteins) is a risk factor for HCM, which is increased by the Amerindian component and can play an important role in the etiology and progression of disease in Mexican patients

  6. four Greek Gypsy patients with limb girdle muscular dystrophy type 2C carried the same homozygous C283Y mutation in the gamma-sarcoglycan gene

  7. The relative incidence of LGMD2C among Japanese Duchenne muscular dystrophy (show DMD Proteins)-like patients can be calculated as 1 in 161 patients suspected to have Duchenne muscular dystrophy (show DMD Proteins).

  8. Clinical, histologic, and immunohistochemical characteristics of three children with limb-girdle muscular dystrophy type 2C. Two novel mutations in the gamma-sarcoglycan gene were present. We found phenotypic differences in two brothers.

  9. Biglycan (show BGN Proteins) is a ligand for two members of the sarcoglycan (show SGCD Proteins) complex and regulates their expression at discrete developmental ages.

  10. The limb-girdle muscular dystrophy patients with gamma-sarcoglycan deficient LGMD2C do not enable an accurate prediction of the genotype.

Mouse (Murine) Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) interaction partners

  1. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx (show DMD Proteins) mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size.

  2. These results position archvillin (show SVIL Proteins) as a mechanically sensitive component of the dystrophin (show DMD Proteins) complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus.

  3. This study supports a model where dystrophin (show DMD Proteins), but not the sarcoglycans, protects the cardiac myocyte against mechanical damage.

  4. localization of gamma-SG does not require Tyr (show TYR Proteins)(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation

  5. The limb, shoulder, and pelvic muscles of the gsg-/- mice exhibited progressive muscle hypertrophy and weakness with age, and the findings were similar to those seen in other mouse models for limb-girdle and Duchenne muscular dystrophy (show DMD Proteins).

  6. In sarcoglycan (show SGCD Proteins) mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation.

  7. delta- and gamma-sarcoglycan prevent vascular spasm in coronary arteries and in vascular smooth muscle

  8. sarcoglycan (show SGCD Proteins) and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction

  9. Sarcoglycan gamma missense mutations affect sarcoglycan (show SGCD Proteins) complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan (show SGCD Proteins) mutations in muscular dystrophies.

Sarcoglycan, gamma (35kDa Dystrophin-Associated Glycoprotein) (SGCG) Protein Profile

Protein Summary

This gene encodes gamma-sarcoglycan, one of several sarcolemmal transmembrane glycoproteins that interact with dystrophin. The dystrophin-glycoprotein complex (DGC) spans the sarcolemma and is comprised of dystrophin, syntrophin, alpha- and beta-dystroglycans and sarcoglycans. The DGC provides a structural link between the subsarcolemmal cytoskeleton and the extracellular matrix of muscle cells. Defects in the encoded protein can lead to early onset autosomal recessive muscular dystrophy, in particular limb-girdle muscular dystrophy, type 2C (LGMD2C).

Gene names and symbols associated with SGCG

  • sarcoglycan, gamma (sgcg)
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (SGCG)
  • sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) (Sgcg)
  • sarcoglycan, gamma (dystrophin-associated glycoprotein) (Sgcg)
  • 35DAG protein
  • 35kDa protein
  • 5430420E18Rik protein
  • A4 protein
  • AI642964 protein
  • DAGA4 protein
  • DMDA protein
  • DMDA1 protein
  • gamma-SG protein
  • LGMD2C protein
  • MAM protein
  • SCARMD2 protein
  • SCG3 protein
  • TYPE protein
  • zgc:100924 protein

Protein level used designations for SGCG

gamma-sarcoglycan , 35 kDa dystrophin-associated glycoprotein , 35DAG , 35kD dystrophin-associated glycoprotein , gamma sarcoglycan , gamma-SG , sgcg gene for gamma-sarcoglycan , sarcoglycan, gamma (35kD dystrophin-associated glycoprotein)

GENE ID SPECIES
445292 Danio rerio
6445 Homo sapiens
486043 Canis lupus familiaris
100272144 Sus scrofa
506155 Bos taurus
100009214 Oryctolagus cuniculus
101825067 Mesocricetus auratus
24053 Mus musculus
305941 Rattus norvegicus
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