anti-Scavenger Receptor Class B, Member 2 (SCARB2) Antibodies

The protein encoded by SCARB2 is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Additionally we are shipping SCARB2 Proteins (14) and SCARB2 Kits (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCARB2 950 Q14108
SCARB2 12492 O35114
SCARB2 117106 P27615
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Top anti-SCARB2 Antibodies at antibodies-online.com

Showing 10 out of 71 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB EB09295 (0.1µg/ml) staining of Human Cerebral Cortex lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged SCARB2 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chinese Hamster Rabbit Un-conjugated ICC, FACS, IF, IHC (p), IHC, WB Detection of SR-BII in Jurkat whole cell lysate using ABIN152881. Lane 1: 1:1000 Lane 2: 1:500 Lane 3: 1:100 Western Blot: SR-BII Antibody [ABIN152881] - Western blot analysis of SR-BII in 1. Human heart lysate 2. Mouse heart lysate 0.1 mL Log in to see 7 to 9 Days
$447.56
Details
Dog Rabbit Un-conjugated ICC, IF, IHC (p), IP, IHC, WB Staining of LIMP II in rat infarctzone tissue using ABIN152898 with a DAB detection system. 0.1 mL Log in to see 7 to 9 Days
$473.81
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: LIMPII/SR-B2 Antibody [NBP1-28914] - (3.8ug/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details
Human Goat Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

SCARB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SCARB2 Antibodies

  1. Chinese Hamster Polyclonal SCARB2 Primary Antibody for ICC, FACS - ABIN152881 : Huby, Doucet, Dachet, Ouzilleau, Ueda, Afzal, Rubin, Chapman, Lesnik: Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues. in The Journal of clinical investigation 2006 (PubMed)
    Show all 12 references for 152881

  2. Dog (Canine) Polyclonal SCARB2 Primary Antibody for ICC, IF - ABIN152898 : Balreira, Gaspar, Caiola, Chaves, Beirão, Lima, Azevedo, Miranda: A nonsense mutation in the LIMP-2 gene associated with progressive myoclonic epilepsy and nephrotic syndrome. in Human molecular genetics 2008 (PubMed)
    Show all 10 references for 152898

  3. Mouse (Murine) Polyclonal SCARB2 Primary Antibody for ELISA - ABIN2000221 : Crombie, Silverstein: Lysosomal integral membrane protein II binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif. in The Journal of biological chemistry 1998 (PubMed)
    Show all 6 references for 2000221

  4. Human Monoclonal SCARB2 Primary Antibody for ELISA - ABIN394954 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for 394954

  5. Human Polyclonal SCARB2 Primary Antibody for IHC (p), IHC - ABIN449974 : Berkovic, Dibbens, Oshlack, Silver, Katerelos, Vears, Lüllmann-Rauch, Blanz, Zhang, Stankovich, Kalnins, Dowling, Andermann, Andermann, Faldini, DHooge, Vadlamudi, Macdonell, Hodgson, Bayly, Savige et al.: Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis. ... in American journal of human genetics 2008 (PubMed)

  6. Human Polyclonal SCARB2 Primary Antibody for IHC, ELISA - ABIN361195 : Murphy, Gysbers, Abbott, Tayebi, Kim, Sidransky, Cooper, Garner, Halliday: Reduced glucocerebrosidase is associated with increased ?-synuclein in sporadic Parkinson's disease. in Brain : a journal of neurology 2014 (PubMed)

More Antibodies against SCARB2 Interaction Partners

Zebrafish Scavenger Receptor Class B, Member 2 (SCARB2) interaction partners

  1. This work describes a novel function for the Scarb2 receptor as an essential glycoprotein for notochord development.

Human Scavenger Receptor Class B, Member 2 (SCARB2) interaction partners

  1. The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.

  2. The findings identify SR-BII as a functional SAA (show SAA1 Antibodies) receptor that mediates SAA (show SAA1 Antibodies) uptake and contributes to its proinflammatory signaling via the MAPK (show MAPK1 Antibodies)-mediated signaling pathways.

  3. In this paper we provide an updated overview of the clinical and genetic features of SCARB2-related PME (show CSTB Antibodies) and on the functions of the LIMP2 protein [review]

  4. neutrophils are able to drive a macrophage activation that would regulate the increase in LIMP-2 expression during the early phase of Cer (show CBLN1 Antibodies)-induced acute pancreatitis

  5. Findings suggested that STX1B (show STX1B Antibodies) rs4889603, FAM47E rs6812193 and SCARB2 rs6825004 do not confer a significant risk for Parkinson's disease

  6. LIMPII was increased greater than twofold in urinary microvesicles obtained from patients with idiopathic membranous nephropathy compared to microvesicles of patients with idiopathic focal segmental glomerulosclerosis and normal controls.

  7. hSR-BII (show CACNA1E Antibodies), and to a lesser extent hSR-BI, significantly increase LPS (show IRF6 Antibodies)-induced inflammation and contribute to LPS (show IRF6 Antibodies)-induced tissue injury in the liver and kidney, two major organs susceptible to LPS (show IRF6 Antibodies) toxicity.

  8. Although hrGCase cellular uptake is independent of LIMP-2, its trafficking to the lysosomes is mediated by this receptor.

  9. SNCA (show SNCA Antibodies) and SCARB2 loci are also associated with dementia with Lewy bodies, after a study-wise Bonferroni correction, although these have a different association profile than the associations reported for the same loci in Parkinson's.

  10. a novel mutation in SCARB2 as a cause of progressive myoclonus epilepsy in China

Mouse (Murine) Scavenger Receptor Class B, Member 2 (SCARB2) interaction partners

  1. The findings identify SR-BII as a functional SAA (show SAA1 Antibodies) receptor that mediates SAA (show SAA1 Antibodies) uptake and contributes to its proinflammatory signaling via the MAPK (show MAPK1 Antibodies)-mediated signaling pathways.

  2. AP-3 (show AP3B1 Antibodies)-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 (show PRDX6 Antibodies) in vitro and in vivo

  3. Heterologous expression of the luminal domain of LIMP-2 in wild-type cells.

  4. In LIMP-2-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein (show SNCA Antibodies) accumulation.

  5. absence of Limp-2 reduces inflammation in experimental crescentic glomerulonephritis with decreased macrophage and T-cell infiltration in the kidney.

  6. Limp-2 deficiency leads to a minor increase in circulating renin (show REN Antibodies). Limp-2, however, is not required for acute or chronic stimulation of renin (show REN Antibodies) release.

  7. The SR-BII is involved in cholesterol ester uptake for steroidogenesis and spermatogenesis in the testis.

  8. The residues between 144 and 151 are critical for SCARB2 binding to VP1 of EV71 and seven residues from the human receptor could convert murine SCARB2, an otherwise inefficient receptor, to an efficient receptor for EV71 viral infection.

  9. The data suggest that tubular proteinuria in Limp-2(-/-) mice is due to failure of endosomes containing reabsorbed proteins to fuse with lysosomes in the proximal tubule of the kidney. Failure of proteolysis is a novel mechanism for tubular proteinuria.

  10. The coiled-coil structure of LIMP-2 is required for its interaction with beta-glucocerebrosidase (show GBA Antibodies).

SCARB2 Antigen Profile

Protein Summary

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SCARB2

  • scavenger receptor class B, member 2 (scarb2) antibody
  • scavenger receptor class B, member 2 (SCARB2) antibody
  • scavenger receptor class B, member 2 (Scarb2) antibody
  • 9330185J12Rik antibody
  • AMRF antibody
  • Cd36l2 antibody
  • chunp6914 antibody
  • EPM4 antibody
  • fi13c07 antibody
  • HLGP85 antibody
  • LGP85 antibody
  • LIMP-2 antibody
  • LimpII antibody
  • MLGP85 antibody
  • scarb2 antibody
  • SR-BII antibody
  • wu:fi13c07 antibody

Protein level used designations for SCARB2

CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 , CD36 antigen-like 2 , lysosome membrane protein 2 , scavenger receptor class B, member 2 , lysosome membrane protein 2-like , putative lysosomal integral membrane protein II , 85 kDa lysosomal membrane sialoglycoprotein , 85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2 , CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II) , LIMP II , lysosome membrane protein II

GENE ID SPECIES
192340 Danio rerio
422638 Gallus gallus
461239 Pan troglodytes
549311 Xenopus (Silurana) tropicalis
699990 Macaca mulatta
100026052 Monodelphis domestica
100455864 Pongo abelii
100190617 Taeniopygia guttata
100397594 Callithrix jacchus
100470627 Ailuropoda melanoleuca
100593903 Nomascus leucogenys
533177 Bos taurus
950 Homo sapiens
12492 Mus musculus
117106 Rattus norvegicus
478435 Canis lupus familiaris
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