anti-Scleraxis (SCX) Antibodies

SCX encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation.

list all antibodies Gene Name GeneID UniProt
SCX 20289 Q64124
Anti-Rat SCX SCX 680712  
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Top anti-Scleraxis Antibodies at

Showing 2 out of 2 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SCXA Antibody (C-term) Cat.-No AP53819PU-N in Mouse cerebellum tissue lysates (35ug/lane). This demonstrates the SCXA antibody detected the SCXA protein (arrow). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 7 to 9 Days

SCX Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine)


Top referenced anti-Scleraxis Antibodies

  1. Human Polyclonal SCX Primary Antibody for EIA, WB - ABIN954689 : Furumatsu, Shukunami, Amemiya-Kudo, Shimano, Ozaki: Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription. in The international journal of biochemistry & cell biology 2009 (PubMed)
    Show all 4 references for 954689

More Antibodies against Scleraxis Interaction Partners

Mouse (Murine) Scleraxis (SCX) interaction partners

  1. scleraxis was required for TGFbeta (show TGFB1 Antibodies)-induced fibronectin (show FN1 Antibodies) expression: TGFbeta (show TGFB1 Antibodies) lost its ability to induce fibronectin (show FN1 Antibodies) expression following scleraxis knockdown.

  2. The phosphorylation sequence matched that targeted by Casein Kinase 2, and inhibition of this kinase activity disrupted the ability of scleraxis to modulate the expression of its target genes while also attenuating TGFbeta (show TGFB1 Antibodies)-induced expression of type I collagen and myofibroblast phenotype conversion marker genes

  3. Cardiac fibroblast phenotype regulation by scleraxis.

  4. scleraxis, a transcription factor critically involved in embryonic tendon development and formation, plays a pivotal role in the fate determination of mesenchymal stem cells towards tenocyte differentiation.

  5. deletion of Scx led to impairments in enthesis structure.

  6. several mRNAs are affected by alternative splicing events in the absence of Scx, suggesting additional roles in post-transcriptional modification.

  7. Expression and function of scleraxis in the developing auditory system.

  8. These studies identify an important role for Scx in regulating proteoglycans in embryonic and mature valve cells.

  9. paratenon cells, which normally do not express Scx, respond to injury by turning on Scx and assembling matrix to bridge the defect

  10. Smad3 (show SMAD3 Antibodies) binds Scleraxis and Mohawk and regulates tendon matrix organization.

Scleraxis (SCX) Antigen Profile

Protein Summary

This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction.

Gene names and symbols associated with anti-Scleraxis (SCX) Antibodies

  • scleraxis (Scx) antibody
  • scleraxis (SCX) antibody
  • BB114693 antibody
  • Bhlha41 antibody
  • Scl antibody

Protein level used designations for anti-Scleraxis (SCX) Antibodies

basic helix-loop-helix transcription factor scleraxis , scleraxis

20289 Mus musculus
680712 Rattus norvegicus
100125857 Equus caballus
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