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Scleraxis Homolog A (Mouse) Proteins (SCXA)

SCXA encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. Additionally we are shipping Scleraxis Homolog A (Mouse) Antibodies (19) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCXA 20289 Q64124
SCXA 100129885 Q7RTU7
SCXA    
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Top Scleraxis Homolog A (Mouse) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$2,445.67
Details

SCXA Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human

Chicken

More Proteins for Scleraxis Homolog A (Mouse) (SCXA) Interaction Partners

Mouse (Murine) Scleraxis Homolog A (Mouse) (SCXA) interaction partners

  1. Cardiac fibroblast phenotype regulation by scleraxis.

  2. scleraxis, a transcription factor critically involved in embryonic tendon development and formation, plays a pivotal role in the fate determination of mesenchymal stem cells towards tenocyte differentiation.

  3. deletion of Scx led to impairments in enthesis structure.

  4. several mRNAs are affected by alternative splicing events in the absence of Scx, suggesting additional roles in post-transcriptional modification.

  5. Expression and function of scleraxis in the developing auditory system.

  6. These studies identify an important role for Scx in regulating proteoglycans in embryonic and mature valve cells.

  7. paratenon cells, which normally do not express Scx, respond to injury by turning on Scx and assembling matrix to bridge the defect

  8. Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization.

  9. Findings suggest a modular model for bone development, involving a distinct pool of Sox9 (show SOX9 Proteins)- and Scx-positive progenitor cells that form bone eminences under regulation of TGFbeta (show TGFB1 Proteins) and BMP4 (show BMP4 Proteins) signaling

  10. the Scx(+)/Sox9 (show SOX9 Proteins)(+) progenitor pool is a unique multipotent cell population that gives rise to tenocytes, ligamentocytes and chondrocytes for the establishment of the chondro-tendinous/ligamentous junction

Scleraxis Homolog A (Mouse) (SCXA) Protein Profile

Protein Summary

This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene product regulates collagen type I gene expression in cardiac fibroblasts and myofibroblasts, and it may play a role in myocardial remodeling. The protein is expressed in the scar area of the adult heart following myocardial infarction.

Gene names and symbols associated with SCXA

  • scleraxis (Scx)
  • scleraxis homolog A (mouse) (SCXA)
  • scleraxis homolog B (mouse) (SCXB)
  • BB114693 protein
  • bHLHa41 protein
  • Scl protein
  • SCX protein

Protein level used designations for SCXA

basic helix-loop-helix transcription factor scleraxis , class A basic helix-loop-helix protein 41 , class A basic helix-loop-helix protein 48 , class II bHLH protein scleraxis

GENE ID SPECIES
20289 Mus musculus
100129885 Homo sapiens
374101 Gallus gallus
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