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anti-Sclerostin Domain Containing 1 (SOSTDC1) Antibodies

SOSTDC1 is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. Additionally we are shipping SOSTDC1 Kits (17) and SOSTDC1 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SOSTDC1 266803 Q642G2
SOSTDC1 25928 Q6X4U4
SOSTDC1 66042 Q9CQN4
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Top anti-SOSTDC1 Antibodies at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SOSTDC1 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SOSTDC1 antibody detected the SOSTDC1 protein (arrow). SOSTDC1 Antibody (C-term)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the SOSTDC1 antibody detected the SOSTDC1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

SOSTDC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus) ,


Human , ,


, , , , ,
Mouse (Murine) , ,


,

More Antibodies against SOSTDC1 Interaction Partners

Human Sclerostin Domain Containing 1 (SOSTDC1) interaction partners

  1. Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 (show CCNA2 Antibodies) and cyclin E2 (show CCNE2 Antibodies).

  2. Results conclude that the transcriptional repressor E4BP4 (show NFIL3 Antibodies) plays a role in repressing epigenetically regulated SOSTDC1 expression in breast cancer cells, which can be reverted by E4BP4 (show NFIL3 Antibodies) silencing.

  3. Epigenetic silencing of SOSTDC1 through methylation is increased in prostate cancer and is associated with accelerated disease progression in patients with prostate cancer

  4. Unliganded VDR (show CYP27B1 Antibodies) upregulates the expression of hairless (show HR Antibodies), the gene product of which acts as a downstream comodulator to feedback-repress DKKL1 (show DKKL1 Antibodies) and SOSTDC1.

  5. DNA methylation (show HELLS Antibodies) is involved in the down-regulation of SOSTDC1 expression in gastric cancer.

  6. SOSTDC1 is expressed in normal breast tissue and this expression is reduced in breast cancer.

  7. Results indicate for the first time that the genetic polymorphisms in SOSTDC1 have an effect on attainment and maintenance of peak bone mass in Chinese women.

  8. genetic aberrations near SOSTDC1 are not uncommon in renal cancer, and occur in adult as well as pediatric renal tumors.

  9. Data suggest that ectodin is a novel bone morphogenetic protein (BMP) inhibitor which integrates BMP signaling with the SHH and FGF signal pathways

  10. USAG1 is expressed in the kidney and functions as a bone morphogenetic protein antagonist.

Mouse (Murine) Sclerostin Domain Containing 1 (SOSTDC1) interaction partners

  1. the in vivo inter-relationships between Bmp7 (show BMP7 Antibodies) and Usag-1, was examined.

  2. Findings strongly suggest that Wise and Sost (show SOST Antibodies) are key modulators of bone development through the ability of their encoded proteins to interact with Lrp5 (show LRP5 Antibodies) and control the balance or levels of Wnt (show WNT2 Antibodies) signaling.

  3. Interactions between BMP-7 (show BMP7 Antibodies) and USAG-1 (uterine sensitization-associated gene-1) regulate supernumerary organ formations

  4. Sost (show SOST Antibodies) and its paralog Sostdc1 coordinate digit number in a Gli3 (show GLI3 Antibodies)-dependent manner.

  5. Wise controls the number and distribution of the mammary epithelial cells via inhibition of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  6. Data suggest that Sostdc1 primarily regulates bone morphogenetic protein pathway in pancreatic islets; knockout/mutation of Sostdc1 enhances down-regulation of Ctgf (connective tissue growth factor (show CTGF Antibodies)) and gremlin (show GREM1 Antibodies) in islets after high-fat diet.

  7. The data demonstrate that simvastatin contributes to prevent the progression of renal fibrosis by upregulating BMP-7 (show BMP7 Antibodies)-mediated anti-fibrotic signaling and that one aspect of crucial efficacies is achieved by regulating HOXA13 (show HOXA13 Antibodies) and USAG-1.

  8. The data suggested that functions of Sostdc1 can be largely attributed to its ability to attenuate Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  9. We propose a new reaction-diffusion model in which Wnt (show WNT2 Antibodies), Shh (show SHH Antibodies) and Sostdc1 act as the activator, mediator and inhibitor, respectively, and confirm that such interactions can generate the tooth pattern of a wild-type mouse.

  10. analyses demonstrate that the Fgf and Shh (show SHH Antibodies) pathways are major downstream targets of Wise-regulated Wnt (show WNT2 Antibodies) signaling.

SOSTDC1 Antigen Profile

Protein Summary

This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.

Gene names and symbols associated with SOSTDC1

  • sclerostin domain containing 1 (SOSTDC1) antibody
  • sclerostin domain containing 1a (sostdc1a) antibody
  • sclerostin domain containing 1 (Sostdc1) antibody
  • 0610006G05Rik antibody
  • DKFZp469J0531 antibody
  • ectodin antibody
  • SOSTDC1 antibody
  • Sostl antibody
  • USAG-1 antibody
  • USAG1 antibody
  • WISE antibody
  • zgc:110293 antibody

Protein level used designations for SOSTDC1

sclerostin domain containing 1 , sclerostin domain-containing protein 1 , Sclerostin domain-containing protein 1 , USAG-1 , uterine sensitization-associated gene 1 protein , wnt-signaling modulator , cystine-knot containing secreted protein , ectodermal BMP inhibitor , uterine sensitization-associated protein-1 , sclerostin-like protein , uterine sensitization-associated protein 1 , context-dependent activator and inhibitor of Wnt signalling protein Wise

GENE ID SPECIES
482331 Canis lupus familiaris
550261 Danio rerio
100173799 Pongo abelii
266803 Rattus norvegicus
25928 Homo sapiens
66042 Mus musculus
378800 Gallus gallus
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