You are viewing an incomplete version of our website. Please click to reload the website as full version.

Sec61 alpha 1 Subunit (S. Cerevisiae) Proteins (SEC61A1)

The protein encoded by SEC61A1 has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. Additionally we are shipping Sec61 alpha 1 Subunit (S. Cerevisiae) Antibodies (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEC61A1 29927 P61619
SEC61A1 53421 P61620
Rat SEC61A1 SEC61A1 80843 P61621
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Sec61 alpha 1 Subunit (S. Cerevisiae) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details

SEC61A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) Interaction Partners

Human Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

  1. Nuclear envelope associated endosome-mediated transfer depends on the nuclear envelope proteins SUN1 (show SUN1 Proteins) and SUN2 (show SUN2 Proteins), as well as the Sec61 translocon complex.

  2. Cotransin, a substrate-selective Sec61 inhibitor, traps nascent transmembrane domains in the cytosolic vestibule, permitting detailed interrogation of an early pre-integration intermediate.

  3. BiP (show GDF10 Proteins) facilitates Sec61 channel closure (i.e. limits ER Ca(2 (show CA2 Proteins)+) leakage) via the Sec61 channel with the help of ERj3 (show DNAJB11 Proteins) and ERj6

  4. Sec61 complex is calcium permeable, the Sec61 complex is tightly regulated in its equilibrium between the closed and open conformations, or "gated", by ligands, such as signal peptides of the transport substrates

  5. Short secretory proteins appear to be ubiquitously transported across the ER membrane through the Sec61 translocon.

  6. The human SEC61A1 gene is essential for cell growth and viability.

  7. BiP (show GDF10 Proteins) limits ER Ca(2 (show CA2 Proteins)+) leakage through the Sec61 complex by binding to the ER lumenal loop 7 of Sec61alpha in the vicinity of tyrosine 344.

  8. The present study indicates that Sec61alpha is a host protein involved in Ebola virus (EBOV) replication, specifically in EBOV genome transcription and replication.

  9. Silencing the SEC61A1 gene using two different siRNAs in HeLa cells for 96 hours had little effect on cell growth and viability. However, calcium leakage from the ER was greatly decreased in the SEC61A1-silenced cells.

  10. At the cellular level, two different calmodulin (show CALM1 Proteins) antagonists stimulated calcium release from the endoplasmic reticulum through SEC61 channels.

Mouse (Murine) Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

  1. Interaction of ribosomes and Sec62 (show TLOC1 Proteins) with the core Sec61 translocon is mutually exclusive.

  2. SEC61A1 gene silencing inhibits co- and post-translational transport of presecretory proteins into endoplasmic reticulum.

  3. Diabetes can bemapped to a point mutation in the Sec61a1 gene that encodes a His to Tyr (show TYR Proteins) substitution at amino acid 344.

Zebrafish Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) interaction partners

  1. A screen for mutations that affect habenular laterality led to the identification of the sec61a-like 1(sec61al1) gene.

Sec61 alpha 1 Subunit (S. Cerevisiae) (SEC61A1) Protein Profile

Protein Summary

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SEC61A1

  • Sec61 alpha 1 subunit (sec61a1)
  • Sec61 alpha 1 subunit (S. cerevisiae) (SEC61A1)
  • preprotein translocase Sec61 subunit alpha (sec61a1)
  • Sec61 alpha 1 subunit (Sec61a1)
  • Sec61 alpha 1 subunit (S. cerevisiae) (Sec61a1)
  • Sec61 alpha 1 subunit (S. cerevisiae) (sec61a1)
  • Sec61 alpha 2 subunit (S. cerevisiae) (SEC61A2)
  • Sec61, alpha subunit 2 (S. cerevisiae) (Sec61a2)
  • similar to S. cerevisiae SEC61 (YLR378C) membrane component of ER protein translocation apparatus (SEC61)
  • AA408394 protein
  • AA410007 protein
  • chunp6898 protein
  • fb62c11 protein
  • HSEC61 protein
  • SEC61 protein
  • Sec61a protein
  • SEC61A1 protein
  • sec61al1 protein
  • sec61alpha protein
  • secY1 protein
  • wu:fb62c11 protein

Protein level used designations for SEC61A1

protein transport protein SEC61 alpha subunit , Sec61 alpha 1 subunit (S. cerevisiae) , transport protein Sec61 alpha subunit , protein transport protein Sec61 subunit alpha isoform 1 , sec61 alpha-1 , Protein transport protein Sec61 subunit alpha , protein transport protein Sec61 subunit alpha-like , Sec61 alpha-1 , protein transport protein Sec61 subunit alpha , sec61 homolog , sec61 homologue , SEC61, alpha subunit , transport protein sec61 alpha subunit , Sec61 alpha subunit homolog , Sec61 alpha form 1 , Sec61 alpha like 1 , protein transport protein Sec61 subunit alpha-like 1 , protein transport protein Sec61 subunit alpha isoform 2 , sec61 alpha-2 , Sec61 alpha form 2 , Sec61 alpha , hypothetical protein

GENE ID SPECIES
379936 Xenopus laevis
416023 Gallus gallus
448033 Xenopus (Silurana) tropicalis
460669 Pan troglodytes
8925650 Haloferax volcanii DS2
100144911 Acyrthosiphon pisum
100173741 Pongo abelii
100413259 Callithrix jacchus
100603743 Nomascus leucogenys
29927 Homo sapiens
404006 Canis lupus familiaris
100155306 Sus scrofa
53421 Mus musculus
80843 Rattus norvegicus
505064 Bos taurus
192298 Danio rerio
614128 Bos taurus
55176 Homo sapiens
57743 Mus musculus
3647462 Candida albicans SC5314
Selected quality suppliers for Sec61 alpha 1 Subunit (S. Cerevisiae) Proteins (SEC61A1)
Did you look for something else?