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The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Additionally we are shipping Sec61 gamma Subunit Antibodies (10) and and many more products for this protein.
Cotransin, a substrate-selective Sec61 (show SEC61A1 ELISA Kits) inhibitor, traps nascent transmembrane domains in the cytosolic vestibule, permitting detailed interrogation of an early pre-integration intermediate.
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. Oligomers of the Sec61 complex form a transmembrane channel where proteins are translocated across and integrated into the ER membrane. This complex consists of three membrane proteins- alpha, beta, and gamma. This gene encodes the gamma-subunit protein. Alternatively spliced transcript variants encoding the same protein have been identified.
protein transport protein SEC61 gamma subunit
, protein transport protein Sec61 subunit gamma
, Sec61-complex gamma-subunit