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SCRN1 likely encodes a member of the secernin family of proteins. Additionally we are shipping Secernin 1 Antibodies (47) and Secernin 1 Proteins (8) and many more products for this protein.
Upregulation of SCRN1 is associated with acquired resistance to erlotinib in non-small cell lung cancer.
Luciferase report assay showed that the rs6976789 variant T allele influenced the binding ability of miR (show MLXIP ELISA Kits)-148a. Our results suggested that the SCRN1 rs6976789 polymorphism may play an important role in the GC development and progression
in synovial sarcoma, metastasis-free survival was significantly higher in the group with high secernin-1 expression compared to low expression; results indicate secernin-1 may be used as a biomarker to predict overall and metastasis-free survival
SCRN1 expression is a prognostic factor in colorectal cancer patients
Purified and identified bovine secernin, in addition to bioinformatics analysis of similar proteins in mouse, rat and human.
Secernin 1 increases both the extent of secretion and increases the sensitivity of mast cells to stimulation with calcium [secernin]
This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described.