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The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. Additionally we are shipping Secretagogin, EF-Hand Calcium Binding Protein Antibodies (77) and Secretagogin, EF-Hand Calcium Binding Protein Kits (9) and many more products for this protein.
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Human SCGN Protein expressed in Escherichia coli (E. coli) - ABIN667217
Gartner, Lang, Leutmetzer, Domanovits, Waldhäusl, Wagner: Cerebral expression and serum detectability of secretagogin, a recently cloned EF-hand Ca(2+)-binding protein. in Cerebral cortex (New York, N.Y. : 1991) 2001
Show all 2 references for ABIN667217
Human SCGN Protein expressed in Escherichia coli (E. coli) - ABIN2005205
Skovhus, Bergholdt, Erichsen, Sparre, Nerup, Karlsen, Pociot: Identification and characterization of secretagogin promoter activity. in Scandinavian journal of immunology 2006
These results suggest SCGN is involved in the chemoresistance of small cell lung cancer under the regulation of miR (show MLXIP Proteins)-494
Scgn is a CaBP expressed in a subpopulation of nociceptive DRG neurons and their processes in the dorsal horn.
While secretagogin mRNA was detected in both peripheral mononuclear cells and erythrocytes using reverse-transcription polymerase chain reaction, SCGN protein was only detected in erythrocytes.
Data show that the density of secretagogin-positive neurons selectively decreases in the olfactory tract in Alzheimer's disease.
Levels of secretagogin correlate with mortality and are useful as predictors of outcome in children with traumatic brain injury.
Ddetection of novel calcium-binding protein (show CETN1 Proteins) secretagogin within subgroup of clear-cell renal cell carcinomas. Increased metastasis rates within secretagogin-positive subgroup of clear-cell renal cell carcinomas.
Results emphasize the developmentally shared origins of neurons populating the extended amygdala, and suggest that secretagogin can be relevant to the generation of functional modalities in specific neuronal circuitries.
Secretagogin might play a role in human non-functional pituitary adenomas. This novel finding may provide clues to clarify the basic molecular mechanisms of pituitary adenoma formation, and to identify new tumor-related markers.
two new variants of the recently identified hexa (show HEXA Proteins)-EF-hand calcium binding protein (show CETN1 Proteins) secretagogin
We identified and characterized promoter activity of a human 1498 bp secretagogin sequence upstream the transcription start site.
X-ray structure of Danio rerio secretagogin: A hexa (show HEXA Proteins)-EF-hand calcium sensor
these data define a novel secretagogin neuronal locus and molecular axis underpinning stress responsiveness.
The Sirt1 (show SIRT1 Proteins)/DDAH2 (show DDAH2 Proteins)/secretagogin pathway is a novel regulator of glucose-stimulated insulin (show INS Proteins) secretion
scgn is a marker of neuroblasts commuting in the rostral migratory stream. Terminally differentiated neurons in the olfactory bulb retain scgn expression, with scgn being present in periglomerular cells and granular layer interneurons.
The encoded protein is a secreted calcium-binding protein which is found in the cytoplasm. It is related to calbindin D-28K and calretinin. This protein is thought to be involved in KCL-stimulated calcium flux and cell proliferation.
secretagogin, EF-hand calcium binding protein