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SECTM1 encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. Additionally we are shipping Secreted and Transmembrane 1 Proteins (9) and Secreted and Transmembrane 1 Kits (4) and many more products for this protein.
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Human Polyclonal SECTM1 Primary Antibody for WB - ABIN2782205
Bade-Döding, Göttmann, Baigger, Farren, Lee, Blasczyk, Huyton: Autocrine GM-CSF transcription in the leukemic progenitor cell line KG1a is mediated by the transcription factor ETS1 and is negatively regulated through SECTM1 mediated ligation of CD7. in Biochimica et biophysica acta 2014
CD7 (show CDK7 Antibodies) is present on monocytes and tumor macrophages and its ligand, SECTM1, is frequently expressed in corresponding melanoma tissues
SECTM1 secreted from bone marrow stromal cells may interact with CD7 (show CDK7 Antibodies) to influence GM-CSF (show CSF2 Antibodies) expression in leukemic cells.
level of SECTM1 expression is likely to be a key factor in innate immune responses and in the immune tolerance of cancerous cells
This gene encodes a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes.
secreted and transmembrane protein 1
, type 1a transmembrane protein
, secreted and transmembrane 1A
, secreted and transmembrane protein 1b