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Secretin Receptor Proteins (SCTR)

The protein encoded by SCTR is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. Additionally we are shipping Secretin Receptor Antibodies (59) and Secretin Receptor Kits (29) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCTR 6344 P47872
SCTR 319229 Q5FWI2
Rat SCTR SCTR 81779 P23811
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Top Secretin Receptor Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details

SCTR Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Secretin Receptor (SCTR) Interaction Partners

Human Secretin Receptor (SCTR) interaction partners

  1. Cysteine trapping identified charge-charge interactions between secretin (show SECR Proteins) and secretin receptor residues in TM5, TM6, ECL2, and ECL3 domains.

  2. Our findings indicate that SCTR suppresses the proliferation of normal breast cells, while the gene stimulates the proliferation and migration of cancer cells being downregulated by promoter methylation.

  3. High SCTR expression is associated with liver metastases of pancreas neuroendocrine tumors.

  4. Results suggest that Secretin (show SECR Proteins) is a potent modulator of adipocyte functions, demonstrating overall a role in enhanced substrate cycling.

  5. Taken together, we propose here that the down-regulatory effects of NRSF on hSCTR gene expression are mediated via its suppression on Sp1 (show PSG1 Proteins)-mediated transactivation.

  6. Data suggest that the interaction between secretin (show SECR Proteins) peptide residue H1 and secretin receptor residue W274 is most compatible with a hydrophobic interaction.

  7. binding and activity of a series of 11 truncated and lactam-constrained secretin (show SECR Proteins)(5-27) analogues at the prototypic member of this family, the secretin receptor

  8. results demonstrate that secretin (show SECR Proteins) and/or the modulation of SCTR expression might have potential as a therapeutic tool in the treatment of cholangiocarcinoma

  9. Increasing expression of secretin receptor competes for receptor modifying protein 3 (show HSPB3 Proteins) (RAMP3 (show RAMP3 Proteins)) association with calcitonin receptor-like receptor (CLR (show CALCRL Proteins)) to yield a functional adrenomedullin receptor (show GPR182 Proteins).

  10. Secretin receptor transcripts are present in Purkinje cells and basket cells in the molecular cell layer of human cerebellum.

Mouse (Murine) Secretin Receptor (SCTR) interaction partners

  1. In vivo, osmotic stress up-regulates the SCTR gene in the kidney cortex and medulla of wild-type mice, but does not do so in NFAT5 (show NFAT5 Proteins)(+/-) mice.

  2. Animal studies demonstrate that secretin receptor (show GPR56 Proteins) deficiency slightly, but significantly, prolongs incubation time in female but not male mice.

  3. Despite similar food intake, SCTR(-/-) mice have less weight, less fat, less hyperleptinemia and better glucose/insulin (show INS Proteins) tolerance on a high-fat diet, and less intestinal fatty acid absorption but similar energy expenditure and locomotor activity.

  4. Immunohistochemical staining of the arcuate nucleus shows colocalization of Sctr with proopiomelanocortin (show POMC Proteins) that provide proof of signals downstream to the paraventricular nucleus that lead to food intake reduction.

  5. Secretin (show SECR Proteins)-deficient mice exhibit decreased numbers of new neurons and increased apoptosis of progenitor cells in the dentate gyrus.

  6. Findings identify SCT (show SECR Proteins) and SCTR as novel elements of the ANGII osmoregulatory pathway in maintaining fluid balance in the body.

Cow (Bovine) Secretin Receptor (SCTR) interaction partners

  1. data indicate that secretin (show SECR Proteins) exerts a direct action on pancreatic secretion through specific SEC-R coupled to the adenylate cyclase system

Secretin Receptor (SCTR) Protein Profile

Protein Summary

The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism.

Gene names and symbols associated with Secretin Receptor Proteins (SCTR)

  • secretin receptor (SCTR)
  • secretin receptor (Sctr)
  • secretin receptor-like (LOC100051620)
  • 6530402O03Rik protein
  • SEC-R protein
  • SR protein

Protein level used designations for Secretin Receptor Proteins (SCTR)

pancreatic secretin receptor , SCT-R

GENE ID SPECIES
6344 Homo sapiens
319229 Mus musculus
81779 Rattus norvegicus
483883 Canis lupus familiaris
523291 Bos taurus
100008671 Oryctolagus cuniculus
100717882 Cavia porcellus
100521045 Sus scrofa
770943 Gallus gallus
101112114 Ovis aries
100051620 Equus caballus
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