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The protein encoded by SCGB3A2 is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. Additionally we are shipping SCGB3A2 Antibodies (5) and SCGB3A2 Kits (4) and many more products for this protein.
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Human SCGB3A2 Protein expressed in Wheat germ - ABIN1319247
Van De Velde, Courtens, Bernard: Development of a new sensitive ELISA for the determination of uteroglobin-related protein 1, a new potential biomarker. in Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2010
This meta-analysis suggests that SCGB3A2 polymorphism at positions -112G>A was associated with Graves' disease both in Chinese and Caucasian population.
the SCGB3A2 -112G >A polymorphism may be considered as a likely marker linking susceptibility to allergy/asthma and Graves' disease
Reduced production of UGRP1, which is likely due, at least in part, to a local cytokine environment, may contribute to the hyper-inflammation in chronic rhinosinusitis and correlates with response to surgery.
This study documents the association between polymorphisms in UGRP1 and the common cold, suggesting a potential role in its pathogenesis.
Results demonstrate that SCGB3A2 is a useful marker for diagnosis of pulmonary tumors both in mice and humans.
pattern of UGRP-1 concentration resembled that of Clara cell protein, both proteins occurring in high concentrations in amniotic fluid, sputum and BALF and in much lower concentrations in serum and urine
association was detected between SCGB3A2 and U.K. Caucasian Graves' disease subjects but the size of effect was smaller than that seen in the Oriental population (odds ratio = 1.28-1.73).
polymorphism in the human UGRP1 gene promoter that regulates transcription is associated with an increased risk of asthma
By in situ hybridization, UGRP1 is found to be expressed by lung Clara-like cells in the bronchial epithelium and up-regulated in lung epithelium of a patient with cystic fibrosis (show S100A8 Proteins).
results demonstrate that interleukin-10 (show IL10 Proteins) induces uteroglobin related protein 1(UGRP1) gene expression in lung epithelial cells through transcription factor T/EBP/NKX2.1 (show NKX2-1 Proteins)-dependent pathway
The pulmonary fibrosis in the Scgb3a2-null mice was more severe than the wild-type controls, thus establishing that SCGB3A2 has anti-fibrotic activity in vivo.
SCGB3A2 is an anti-fibrotic agent, and suggest a possible therapeutic use of recombinant SCGB3A2 in the treatment of pulmonary fibrosis.
The results indicate that the loss of SCGB3A2 function was influenced by a modifier gene(s) in mixed genetic background and suggest that SCGB3A2 has anti-inflammatory property.
SCGB3A2 regulates FSH (show BRD2 Proteins)/LH production in the anterior pituitary lobe.
Secretoglobin (show SCGB3A1 Proteins) 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation
Highest HIN-1 (show SCGB3A1 Proteins) and UGRP-1 expression is detected in the lung, while lower level HIN-1 (show SCGB3A1 Proteins) expression is also detected in the stomach, heart, small intestine, uterine and mammary glands
UGRP1 does not play a major role in the development of bronchial asthma in our Caucasian population.
UGRP1 is downregulated in inflamed airways, such as allergic asthmatics.
The protein encoded by this gene is a secreted lung surfactant protein and a downstream target of thyroid transcription factor. A single nucleotide polymorphism in the promoter of this gene results in susceptibility to asthma.
secretoglobin, family 3A, member 2
, secretoglobin family 3A member 2
, pneumo secretory protein 1
, uteroglobin-related protein 1
, uteroglobin related protein 1