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Secretogranin II Proteins (SCG2)

The protein encoded by SCG2 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Additionally we are shipping Secretogranin II Antibodies (87) and Secretogranin II Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCG2 7857 P13521
SCG2 24765 P10362
SCG2 20254 Q03517
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Top Secretogranin II Proteins at antibodies-online.com

Showing 9 out of 15 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag,GST tag 100 μg Log in to see 11 to 13 Days
$795.30
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,694.17
Details
HOST_HEK-293 Cells Human His tag   50 μg Log in to see 5 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$967.75
Details
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$160.55
Details

SCG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Rat (Rattus)

Mouse (Murine)
,

More Proteins for Secretogranin II (SCG2) Interaction Partners

Human Secretogranin II (SCG2) interaction partners

  1. Differential Reovirus-Specific and Herpesvirus-Specific Activator Protein 1 (show FOSB Proteins) Activation of Secretogranin II Leads to Altered Virus Secretion.

  2. present data show that SgII (show SEMG2 Proteins) is highly expressed in advanced prostate cancer and may contribute to the neuroendocrine differentiation by promoting the formation of secretory granules and the proliferation of PCa (show FLVCR1 Proteins) cells.

  3. SN induces MUC5AC hypersecretion in a dose- and time-dependent manner; moreover, the MUC5AC over synthesis induced by SN is strongly associated with the enhanced binding of EGF (show EGF Proteins) to NRP1 (show NELL1 Proteins)

  4. Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF (show FHL2 Proteins).

  5. CgA (show CGA Proteins), CgB (show CGB Proteins), and secretoneurin are detectable in feces, and collagenous colitis patients express higher values than patients with inflammatory bowel disease and controls. In treatment, fecal secretoneurin decreased to control levels in collagenous colitis.

  6. In vivo secretoneurin improves left ventricular function, inhibits remodeling, and reduces scar formation; in the infarct border zone, secretoneurin induces coronary angiogenesis.

  7. Circ (show SEMG2 Proteins)ulating Levels of SgII are Increased in Patients with chronic, stable heart failure.

  8. Data describe the gene expression and protein production of SgII (show SEMG2 Proteins) in normal adrenal glands and pheochromocytomas with the goal to examine the molecular mechanisms leading to the marked variations in the expression of EM66 in tumoral chromaffin tissue.

  9. This short review deals with investigations in neuroendocrine tumors (NETs) with antibodies against defined epitopes of chromogranins (Cgs) A and B and secretogranins (Sgs (show FBN1 Proteins)) II and III.

  10. More SgII (show SEMG2 Proteins) immunoreactive cells were observed in phaeochromocytomas.

Mouse (Murine) Secretogranin II (SCG2) interaction partners

  1. Scg2 is a major secretory target of REST with a cell differentiation-enhancing activity in neural stem cells.

  2. Topical secretoneurin gene therapy accelerates diabetic wound healing by interaction between heparan-sulfate proteoglycans and basic FGF (show FHL2 Proteins).

  3. Scg2 is a good candidate for the signal integrator required for activity-dependent plasticity such as associative learning and memory.

  4. SgII binds directly to the secretory granule membrane and controls intracellular retention of proopiomelanocortin (show POMC Proteins) in AtT-20 cells.

  5. SgII mRNA levels were 10.5 fold upregulated in the left ventricle of animals with myocardial infarction and heart failure.

  6. SN activates the protein kinase A (PKA) and cAMP-induced ERK (show EPHB2 Proteins) signaling pathways in the LH-secreting mouse LbetaT2 pituitary cell line

  7. The wide subcellular localization of secretogranin II in mouse brain may reflect diverse release sites of neuropeptides and secretorneurin, or suggests its role in the sorting and packaging of molecules other than neuropeptides in non-LDCV compartments.

  8. SCG2, as well as SCG3 (show SCG3 Proteins), may be a potential regulator of food intake based on its capacity to accumulate appetite-related hormones into secretory granules.

Cow (Bovine) Secretogranin II (SCG2) interaction partners

  1. secretogranin II-derived peptide EM66 may act downstream of the trans-synaptic stimulation of the adrenal medulla by neurocrine factors

  2. Results show the localization of secretogranin II (SgII) in the nucleus, more specifically, in the IP3-sensitive nucleoplasmic Ca2 (show CA2 Proteins)+ store vesicles along with CGB (show CHGB Proteins) and the IP3 receptors.

Pig (Porcine) Secretogranin II (SCG2) interaction partners

  1. Comparative sequencing and EST analysis revealed nine SNPs in porcine SCG2 cDNA, including seven SNPs in the coding region and two SNPs in the 3' UTR.

Secretogranin II (SCG2) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Studies in rodents suggest that the full-length protein, secretogranin II, is involved in the packaging or sorting of peptide hormones and neuropeptides into secretory vesicles. The full-length protein is cleaved to produce the active peptide secretoneurin, which exerts chemotaxic effects on specific cell types, and EM66, whose function is unknown.

Gene names and symbols associated with Secretogranin II Proteins (SCG2)

  • secretogranin II (LOC397939)
  • secretogranin II (chromogranin C), b (scg2b)
  • secretogranin II (scg2)
  • secretogranin II (SCG2)
  • secretogranin II (chromogranin C) (SCG2)
  • Secretogranin-2 (scg2)
  • secretogranin II (Scg2)
  • Chcg protein
  • Chgc protein
  • DKFZp459O193 protein
  • EM66 protein
  • LOC397939 protein
  • MGC84703 protein
  • MGC145924 protein
  • SCG2 protein
  • SCGG2 protein
  • SgII protein
  • SN protein
  • wu:fj34e01 protein
  • zgc:153925 protein

Protein level used designations for Secretogranin II Proteins (SCG2)

secretogranin II , secretogranin-2 , secretogranin-2-like , secretogranin II (chromogranin C) , Secretogranin-2 , chromogranin-C , secretoneurin , Chromogranin C (Secretogranin II) , secretogranin 2 , sgII , chromogranin C

GENE ID SPECIES
397939 Xenopus laevis
777641 Danio rerio
779764 Xenopus (Silurana) tropicalis
100061099 Equus caballus
100484350 Ailuropoda melanoleuca
100559979 Anolis carolinensis
100174732 Pongo abelii
100196607 Salmo salar
7857 Homo sapiens
24765 Rattus norvegicus
20254 Mus musculus
281477 Bos taurus
497237 Sus scrofa
424808 Gallus gallus
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