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Secretogranin V (7B2 Protein) Proteins (SCG5)

mouse homolog plays a role in the transport and activation of proprotein convertase-2 (PC2)\; may regulate hormone secretion [RGD, Feb 2006].. Additionally we are shipping Secretogranin V (7B2 Protein) Antibodies (29) and Secretogranin V (7B2 Protein) Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SCG5 20394 P12961
SCG5 25719 P27682
SCG5 6447 P05408
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Top Secretogranin V (7B2 Protein) Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$2,365.00
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$2,440.17
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,440.17
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,442.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Escherichia coli (E. coli) Human His tag   2 μg Log in to see 6 to 11 Days
$142.86
Details

SCG5 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,
,

Top referenced Secretogranin V (7B2 Protein) Proteins

  1. Human SCG5 Protein expressed in Escherichia coli (E. coli) - ABIN667198 : Mbikay, Seidah, Chrétien: Neuroendocrine secretory protein 7B2: structure, expression and functions. in The Biochemical journal 2001 (PubMed)
    Show all 2 references for ABIN667198

More Proteins for Secretogranin V (7B2 Protein) (SCG5) Interaction Partners

Mouse (Murine) Secretogranin V (7B2 Protein) (SCG5) interaction partners

  1. Dynamic modulation of prohormone convertase 2 (PC2 (show PCSK2 Proteins))-mediated precursor processing by 7B2 protein has a preferential effect on glucagon (show GCG Proteins) synthesis

  2. 7B2-related peptides modulate regulated secretion of ACTH (show POMC Proteins) in neuroendocrine cells.

  3. 7B2 nulls exhibit a multisystem disorder of vital organs, most notably the liver, in which massive steatosis and necrosis are observed. Metabolic derangements in glucose metabolism result in glycogen (show GYS1 Proteins) and fat deposition in liver

  4. 7B2 has a role in endoproteolytic processing in mouse brain

  5. data indicate that null prohormone convertase 2 (show PCSK2 Proteins) and 7B2 protein are not phenotypically equivalent in pituitary proopiomelanocortin (POMC (show POMC Proteins)) biosynthesis and granule content

  6. Phenotypic differences between the 7B2 and PC2 (show CBX4 Proteins) nulls and play a life-or-death role in the ACTH (show POMC Proteins) hypersecretion syndrome present in both 129 nulls.

  7. phosphorylation of 7B2 functionally inactivates this protein in a manner analogous to the phosphorylating inactivation of BiP (show HSPA5 Proteins), which impairs its ability to bind substrate

  8. Differential expression of 7B2 may contribute to the difference between B6 and C3H mice not only in glucagon (show GCG Proteins) production and secretion but also in glucose tolerance.

  9. a role for Scg5 in the modulation of body weight

  10. 7B2 possesses chaperone activity that blocks partially unfolded pro-PC2 (show CBX4 Proteins) forms from losing catalytic competence and then aggregating.

Human Secretogranin V (7B2 Protein) (SCG5) interaction partners

  1. FAM20C (show FAM20C Proteins) plays a role in 7B2-mediated proPC2 activation by phosphorylating residue Thr111; and that 7B2 function is regulated by alternative splicing.

  2. 7B2 chaperones blocked the cytotoxic effects of exogenous hIAPP

  3. conclude that 7B2 is a natively disordered protein whose function as an antiaggregant chaperone is likely facilitated by its lack of appreciable secondary structure and tendency to form oligomers

  4. data provide insight into novel functions of 7B2 and establish this neural protein as an anti-aggregation chaperone associated with neurodegenerative disease

  5. the significant effects of SGNE1/7B2 on the growth and apoptosis of glioblastoma cells provide a first proof for a functional implication of SGNE1/7B2 inactivation in the molecular pathology of gliomas.

  6. SGNE1 was overexpressed in gastrointestinal peptide (show SPINK4 Proteins)-independent ACTH (show POMC Proteins)-independent macronodular adrenal hyperplasia. hyperplasia

  7. SGNE1 identified as a novel epigenetically silenced gene in medulloblastomas and its inactivation, as well as its inhibitory effect on tumor cell proliferation and focus formation strongly argues for a significant role in medulloblastoma development.

  8. SGNE1 genetic variation does not contribute to obesity and common forms of Type 2 diabetes but may worsen glucose intolerance and insulin (show INS Proteins) resistance, especially in the background of severe and early onset obesity

Secretogranin V (7B2 Protein) (SCG5) Protein Profile

Protein Summary

mouse homolog plays a role in the transport and activation of proprotein convertase-2 (PC2)\; may regulate hormone secretion

Gene names and symbols associated with SCG5

  • secretogranin V (scg5)
  • secretory granule, neuroendocrine protein 1 (7B2 protein) (sgne1)
  • secretogranin V (LOC100341807)
  • secretogranin V (Scg5)
  • secretogranin V (7B2 protein) (Scg5)
  • secretogranin V (7B2 protein) (SCG5)
  • 7B2 protein
  • AI325031 protein
  • MGC145087 protein
  • P7B2 protein
  • Sgne-1 protein
  • SGNE1 protein
  • SgV protein
  • zgc:73132 protein

Protein level used designations for SCG5

neuroendocrine protein 7B2 , secretogranin V , secretogranin-5 , secretory granule endocrine protein I , secretory granule neuroendocrine protein 1, 7B2 protein , Secretory granule neuroendocrine, protein 1 (7B2 protein) , secretory granule neuroendocrine protein 1 , pituitary polypeptide , prohormone convertase chaperone , secretory granule, neuroendocrine protein 1 (7B2 protein) , neuronal endocrine protein

GENE ID SPECIES
393699 Danio rerio
496700 Xenopus (Silurana) tropicalis
100341807 Oryctolagus cuniculus
20394 Mus musculus
25719 Rattus norvegicus
6447 Homo sapiens
397110 Sus scrofa
453292 Pan troglodytes
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