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SCAMP2 product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. Additionally we are shipping Secretory Carrier Membrane Protein 2 Antibodies (41) and many more products for this protein.
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SCAMP2 regulates NKCC2 (show SLC12A1 Proteins) transit through recycling endosomes and limits the cell surface targeting of the co-transporter by interfering with its exocytotic trafficking.
this finding that SCAMP2 interacts with and regulates the subcellular distribution of both DAT (show SLC6A3 Proteins) and SERT (show SLC6A4 Proteins) suggests that interaction with SCAMP2 may constitute an important mechanism for coordinating cell surface expression of monoamine transporters.
SCAMP2 plays an important role in the regulation of the subcellular distribution of SERT (show SLC6A4 Proteins)
The strong correlation between SCAMP2 E interactions with PIP2 and inhibition of exocytosis, particularly by SC2-R204A, led us to propose that SCAMP2 interaction with PIP2 within the membrane interface regulates fusion pore formation during exocytosis.
SCAMP2 regulates NHE5 transit through recycling endosomes and promotes its surface targeting in an Arf6 (show ARF6 Proteins)-dependent manner.
This gene product belongs to the SCAMP family of proteins which are secretory carrier membrane proteins. They function as carriers to the cell surface in post-golgi recycling pathways. Different family members are highly related products of distinct genes, and are usually expressed together. These findings suggest that the SCAMPs may function at the same site during vesicular transport rather than in separate pathways.
secretory carrier membrane protein 2
, secretory carrier-associated membrane protein 2