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Selectin E Proteins (SELE)

The protein encoded by SELE is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. Additionally we are shipping Selectin E + CD62e Antibodies (334) and Selectin E + CD62e Kits (172) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SELE 6401 P16581
SELE 25544 P98105
SELE 20339 Q00690
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Top Selectin E + CD62e Proteins at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$250.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_HEK-293 Human His tag Human recombinant CD62E 100 μg Log in to see 2 to 3 Days
$651.00
Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 2 to 3 Days
$275.00
Details

SELE Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , , ,
Rat (Rattus)
,
Mouse (Murine) , ,
, ,

Top referenced Selectin E + CD62e Proteins

  1. Human Selectin E + CD62e Protein expressed in Human Cells - ABIN2002601 : Phillips, Nudelman, Gaeta, Perez, Singhal, Hakomori, Paulson: ELAM-1 mediates cell adhesion by recognition of a carbohydrate ligand, sialyl-Lex. in Science (New York, N.Y.) 1991 (PubMed)
    Show all 6 references for ABIN2002601

  2. Rat (Rattus) Selectin E + CD62e Protein expressed in Human Cells - ABIN2009077 : Luo, Paranya, Bischoff: Noninflammatory expression of E-selectin is regulated by cell growth. in Blood 1999 (PubMed)
    Show all 5 references for ABIN2009077

  3. Mouse (Murine) Selectin E + CD62e Protein expressed in Human Cells - ABIN2008257 : Hession, Osborn, Goff, Chi-Rosso, Vassallo, Pasek, Pittack, Tizard, Goelz, McCarthy: Endothelial leukocyte adhesion molecule 1: direct expression cloning and functional interactions. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 4 references for ABIN2008257

  4. Cynomolgus Selectin E + CD62e Protein expressed in Human Cells - ABIN2009946 : Hu, Szente, Kiely, Gimbrone: Molecular events in transmembrane signaling via E-selectin. SHP2 association, adaptor protein complex formation and ERK1/2 activation. in The Journal of biological chemistry 2001 (PubMed)
    Show all 4 references for ABIN2009946

More Proteins for Selectin E (SELE) Interaction Partners

Human Selectin E (SELE) interaction partners

  1. The E-selectin S149R polymorphisms is associated with the oncogenesis of breast cancer.

  2. Neisseria meningitidis caused a high level of E-selectin expression elicited by the activity of phosphorylated ATF2 (show ATF2 Proteins) transcription factor on the E-selectin promoter.

  3. E-selectin is more effective than cTnI in diagnosing myocardial injury in children.

  4. Inhibition of E-selectin expression allows an anti-tumoral effect on sLex-expressing hepatocellular carcinoma tumors in vivo

  5. Glycosphingolipids likely contribute to human myeloid cell adhesion to E-selectin under fluid shear, particularly the transition of rolling cells to firm arrest.

  6. Data show that both mucin16 (MUC16 (show MUC16 Proteins)) and podocalyxin (PODXL (show PODXL Proteins))-E-selectin-mediated interactions are mechanically stronger than like L-selectin (show SELL Proteins) interactions at the single-molecule level.

  7. These findings provide consistent evidence that A516C and G98T polymorphisms of the SELE gene may be associated with increased susceptibility of coronary artery disease.

  8. Glaucomatous MYOC (show MYOC Proteins) mutations activate the IL-1beta (show IL1B Proteins)/NF-kappaB (show NFKB1 Proteins) inflammatory stress response and the glaucoma marker SELE in trabecular meshwork cells.

  9. P. gingivalis was shown to activate NOD1 (show NOD1 Proteins), NOD2, and TLR2 expression, resulting in increased E-selectin expression in endothelial cells; direct inhibition of NF-kappaB (show NFKB1 Proteins) and P38 MAPK (show MAPK14 Proteins) significantly attenuated E-selectin expression induced by P. gingivalis in endothelial cells

  10. The number of E-selectin-positive cells was significantly higher in the tuberculoid form than in the lepromatous form of leprosy skin lesions.

Pig (Porcine) Selectin E (SELE) interaction partners

  1. Chitosan oligosaccharides downregulate the expression of E-selectin and ICAM-1 (show ICAM1 Proteins) by inhibiting the phosphorylation of Mitogen-Activated Protein Kinases and the activation of NF-kappaB (show NFKB1 Proteins) in lipopolysaccharides treated porcine iliac artery endothelial cells.

  2. Increased E-selectin mRNA at end of 20 hours of cold ischemia time might indicate a preactivated state of endothelial cells potentially triggered by bacterial translocation or products.

Mouse (Murine) Selectin E (SELE) interaction partners

  1. In a model of corneal transplantation, P- and E-selectin mediate T cell recruitment to the graft, E-selectin mediates APC (show APC Proteins) trafficking to lymphoid tissue, and blockade of E-selectin has a modest effect on improving long-term graft survival.

  2. Social defeat induced an exposure-dependent increase in mRNA levels of E-selectin, CXCL1, and CXCL2 (show CXCL2 Proteins) that increased with additional days of social defeat.

  3. The histopathological modification of lupus nephritis by non-nephritogenic bystander IgM (show CD40LG Proteins) antibodies is associated in part with glomerular E-selectin expression.

  4. Data show that actin cytoskeleton regulated CD44 (show CD44 Proteins) membrane mobility and interactions with E-selectin.

  5. Regulatory T cells dynamically regulate P and E selectin ligand expression during multiple challenge contact hypersensitivity.

  6. Systemic inflammation may increase the expression of E-selectin which mediated the lung metastasis of breast cancer in mouse model.

  7. In the absence of either PSGL-1 (show SELPLG Proteins) or E- and P-selectin (show SELP Proteins).

  8. Elevated E-selectin plays an important role in hepatic neutrophil infiltration and injury induced by chronic-binge feeding in mice and may also contribute to the pathogenesis of early stages of human alcoholic liver disease.

  9. expression of E-selectin and ICAM-1 (show ICAM1 Proteins) are suppressed by paeoniflorin in a mouse model of cutaneous Arthus reaction

  10. Expression of E-selectin is sufficient to support rescue & hematopoietic reconstitution of lethally irradiated recipients forllowing bone marrow transplant.

Selectin E + CD62e (SELE) Protein Profile

Protein Summary

The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.

Gene names and symbols associated with Selectin E Proteins (SELE)

  • selectin E (SELE)
  • selectin E (Sele)
  • selectin, endothelial cell (Sele)
  • CD62E protein
  • E-selectin protein
  • Elam protein
  • ELAM1 protein
  • ESEL protein
  • LECAM2 protein
  • SELE protein

Protein level used designations for Selectin E Proteins (SELE)

selectin E , E-selectin , endothelial adhesion molecule 1 , selectin E (endothelial adhesion molecule 1) , E-selectin-like , e-selectin-like , CD62 antigen-like family member E , ELAM-1 , endothelial leukocyte adhesion molecule 1 , leukocyte endothelial cell adhesion molecule 2 , leukocyte-endothelial cell adhesion molecule 2 , LECAM2 , selectin, endothelial cell

GENE ID SPECIES
443127 Ovis aries
701538 Macaca mulatta
736063 Pan troglodytes
100412914 Callithrix jacchus
100441604 Pongo abelii
100583231 Nomascus leucogenys
6401 Homo sapiens
397508 Sus scrofa
100009151 Oryctolagus cuniculus
403999 Canis lupus familiaris
25544 Rattus norvegicus
281484 Bos taurus
100033910 Equus caballus
20339 Mus musculus
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