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Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) Proteins (SELP)

SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Additionally we are shipping SELP Antibodies (362) and SELP Kits (116) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SELP 25651 P98106
SELP 6403 P16109
SELP 20344 Q01102
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Top SELP Proteins at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse Fc Tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$272.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details

SELP Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) , ,
,
Human , , , , ,
, , , ,
Mouse (Murine) , , ,
, ,

Top referenced SELP Proteins

  1. Human SELP Protein expressed in Human Cells - ABIN2005371 : Johnson-Tidey, McGregor, Taylor, Poston: Increase in the adhesion molecule P-selectin in endothelium overlying atherosclerotic plaques. Coexpression with intercellular adhesion molecule-1. in The American journal of pathology 1994 (PubMed)

More Proteins for Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) Interaction Partners

Human Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Elevated plasma P-selectin autoantibodies may play a role in the pathogenesis of thrombocytopenia in pSS (show CDSN Proteins) patients.

  2. The addition of sialic acid enhances the affinity of CD15 (show FUT4 Proteins) to P-selectin and augments the cell adhesion to blood vessel endothelial cells.

  3. This study provides a better understanding of the biology of P-selectin and PSGL-1 (show SELPLG Proteins) and their roles in dissemination and resensitization of Multiple myeloma treatment.

  4. Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp (show SEPP1 Proteins) and human SELP (show SEPP1 Proteins) genes.

  5. P-selectin gene polymorphisms and haplotypes can contribute to proliferative diabetic retinopathy development.

  6. P-selectin polymorphism of -825T/C is associated with the risk of pulmonary hypertension in congenital heart defects, and may be one of its risk factors.

  7. Soluble P-selectin was upregulated I ankylosing spondylitis patients could predict prognosis.

  8. P-selectin has a role in endothelial progenitor cells' inhibition of platelet function

  9. s. Leukocyte filtration does not affect the CD62P surface expression of apheresis platelets stored for up to 2 days, which indicates that leukocyte filtration does not damage the activation of apheresis platelets within the retention period

  10. Plasmodium falciparum MSP7 and P-selectin were shown to bind each other directly via the N-terminus of PfMSP7 and the P-selectin C-type lectin (show MBL2 Proteins) and EGF (show EGF Proteins)-like domains.

Horse (Equine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Despite the decrease of CD62P expression, the observed increased surface expression of CD41/61 on platelets in horses with recurrent airway obstruction may contribute to the formation of platelet aggregates in their respiratory system.

Mouse (Murine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. The present study supported the notion that CD62P accumulation during platelet storage is involved in mediating transfusion-related acute lung injury.

  2. Holothurian glycosaminoglycan has emerged as a novel anti-cancer agent via blocking P-selectin-mediated malignant events of tumor metastasis.

  3. Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp (show SEPP1 Proteins) and human SELP (show SEPP1 Proteins) genes.

  4. P-selectin has a role in endothelial progenitor cells' inhibition of platelet function

  5. Both platelet and endothelial cell P-selectin contribute to host defense during Klebsiella pneumosepsis.

  6. Platelet infiltration into solid tumors occurs through a P-selectin-dependent mechanism and promotes tumor growth.

  7. P-selectin promotes neutrophil extracellular trap (NET) formation and is a potential target for NET-related diseases.

  8. P-selectin is an important adhesion molecule (show NCAM1 Proteins) vital for infiltration of regulatory T cells into mouse mammary tumors

  9. Administering human recombinant PTX3 (show PITX3 Proteins) to wild-type mice induced endothelial dysfunction and increased blood pressure, an effect absent in P-selectin-deficient mice.

  10. Targeting P-selectin-mediated platelet adhesion onto endometriotic lesions holds promise as a novel therapeutics for treating endometriosis.

SELP Protein Profile

Protein Summary

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene names and symbols associated with SELP

  • selectin P (Selp)
  • selectin P (granule membrane protein 140kDa, antigen CD62) (SELP)
  • selectin P (granule membrane protein 140kDa, antigen CD62) (Selp)
  • selectin, platelet (Selp)
  • CD62 protein
  • CD62P protein
  • GMP-140 protein
  • GMP140 protein
  • Grmp protein
  • LECAM3 protein
  • PADGEM protein
  • PSEL protein
  • PSELECT protein

Protein level used designations for SELP

CD62 antigen-like family member P , GMP-140 , LECAM3 , P-selectin , PADGEM , granule membrane protein 140 , leukocyte-endothelial cell adhesion molecule 3 , platelet activation dependent granule-external membrane protein , selectin, platelet , granulocyte membrane protein , platelet alpha-granule membrane protein , CD62P antigen , cell adhesion molecule

GENE ID SPECIES
25651 Rattus norvegicus
6403 Homo sapiens
100009695 Equus caballus
443305 Ovis aries
397150 Sus scrofa
100009534 Oryctolagus cuniculus
100716162 Cavia porcellus
281486 Bos taurus
403994 Canis lupus familiaris
424364 Gallus gallus
20344 Mus musculus
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