anti-Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) Antibodies

SELP encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Additionally we are shipping SELP Kits (118) and SELP Proteins (38) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SELP 25651 P98106
SELP 6403 P16109
SELP 20344 Q01102
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Top anti-SELP Antibodies at antibodies-online.com

Showing 10 out of 353 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p), WB CD62P (P-Selectin) – ABIN118767 - Human tonsil showing capillary endothelium. Formalin fixed, paraffin processed tissue. 0.2 mg Log in to see 6 to 8 Days
$500.50
Details
Cow Rabbit Un-conjugated WB Western blot analysis of CD62P expression in HEK293T (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Cat Mouse Un-conjugated FACS, ICC, IF, IHC, IHC (fro), IP Staining of thrombin activated human platelets with MOUSE ANTI HUMAN CD62P(ABIN259995). Flow Cytometry: P-Selectin/CD62P Antibody (Psel.KO.2.7) [ABIN2599952] - Staining of thrombin activated human platelets 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon tissue labeled with Anti-P-selectin Polyclonal Antibody (ABIN670131), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat pancreas labeled with Rabbit Anti-CD62p Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Goat Mouse PE FACS Staining of thrombin activated platelets with 100 Tests Log in to see 6 to 8 Days
$434.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB Anti- CD62P Picoband antibody, Western blotting All lanes: Anti CD62P  at 0.5ug/ml Lane 1: A549 Whole Cell Lysate at 40ug Lane 2: K562 Whole Cell Lysate at 40ug Predicted bind size: 91KD Observed bind size: 140KD Anti- CD62P Picoband antibody, IHC(P) IHC(P): Human Tonsil Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IHC (p), IP 0.2 mg Log in to see 6 to 8 Days
$489.50
Details
Human Chicken FITC FACS, WB   100 μL Log in to see 6 to 8 Days
$420.42
Details
Cow Mouse Un-conjugated FACS, IHC (fro), IP Staining of thrombin activated human platelets with ABIN120296 0.2 mg Log in to see 6 to 8 Days
$467.50
Details
Human Mouse Un-conjugated IHC (fro), FACS, IF, IHC (p), WB 0.1 mg Log in to see 3 to 4 Days
$271.76
Details

SELP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SELP Antibodies

  1. Mouse (Murine) Monoclonal SELP Primary Antibody for BR, IHC (fro) - ABIN2689365 : Pendl, Robert, Steinert, Thanos, Eytner, Borges, Wild, Lowe, Fuhlbrigge, Kupper, Vestweber, Grabbe: Immature mouse dendritic cells enter inflamed tissue, a process that requires E- and P-selectin, but not P-selectin glycoprotein ligand 1. in Blood 2002 (PubMed)
    Show all 9 Pubmed References

  2. Mouse (Murine) Monoclonal SELP Primary Antibody for FACS - ABIN2689367 : Aigner, Ruppert, Hubbe, Sammar, Sthoeger, Butcher, Vestweber, Altevogt: Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin. in International immunology 1996 (PubMed)
    Show all 8 Pubmed References

  3. Cat (Feline) Monoclonal SELP Primary Antibody for FACS, ICC - ABIN259995 : Johnson, Wearden, Kocyildirim, Maul, Woolley, Ye, Strickler, Borovetz, Wagner: Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular assist device. in Artificial organs 2011 (PubMed)
    Show all 8 Pubmed References

  4. Mouse (Murine) Monoclonal SELP Primary Antibody for BR, IHC (fro) - ABIN1177016 : Austrup, Vestweber, Borges, Löhning, Bräuer, Herz, Renz, Hallmann, Scheffold, Radbruch, Hamann: P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflammed tissues. in Nature 1997 (PubMed)
    Show all 7 Pubmed References

  5. Human Monoclonal SELP Primary Antibody for Func, ICC - ABIN638443 : Dunlop, Skinner, Bendall, Favaloro, Castaldi, Gorman, Gamble, Vadas, Berndt: Characterization of GMP-140 (P-selectin) as a circulating plasma protein. in The Journal of experimental medicine 1992 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal SELP Primary Antibody for Func, ICC - ABIN810080 : Holme, Müller, Solum, Brosstad, Frøland, Aukrust: Enhanced activation of platelets with abnormal release of RANTES in human immunodeficiency virus type 1 infection. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1998 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal SELP Primary Antibody for Func, ICC - ABIN1981854 : Ludwig, Schultz, Boehncke, Podda, Tandi, Krombach, Baatz, Kaufmann, von Andrian, Zollner: Activated, not resting, platelets increase leukocyte rolling in murine skin utilizing a distinct set of adhesion molecules. in The Journal of investigative dermatology 2004 (PubMed)
    Show all 3 Pubmed References

  8. Mouse (Murine) Monoclonal SELP Primary Antibody for BR, IHC (f) - ABIN2689366 : Yang, Galipeau, Kozak, Furie, Furie: Mouse P-selectin glycoprotein ligand-1: molecular cloning, chromosomal localization, and expression of a functional P-selectin receptor. in Blood 1996 (PubMed)
    Show all 3 Pubmed References

  9. Human Monoclonal SELP Primary Antibody for Func, ICC - ABIN2749072 : Kowalska, Ratajczak, Hoxie, Brass, Gewirtz, Poncz, Ratajczak: Megakaryocyte precursors, megakaryocytes and platelets express the HIV co-receptor CXCR4 on their surface: determination of response to stromal-derived factor-1 by megakaryocytes and platelets. in British journal of haematology 1999 (PubMed)
    Show all 3 Pubmed References

More Antibodies against SELP Interaction Partners

Human Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. P-Selectin and ICAM-1 (show ICAM1 Antibodies) have roles in mediating THP-1 (show GLI2 Antibodies) monocyte adhesion

  2. Transgenic expression of SELP (show SEPP1 Antibodies) is atherogenic in Apoe (show APOE Antibodies)(-/-) mice, suggesting that P-selectin contributes to atherogenesis.

  3. These results provide a novel insight into the mechano-chemical regulation mechanism for P-selectin-induced calcium signaling of neutrophils in flow.

  4. Data indicate no association of maternal or fetal ITGA2 (show ITGA2 Antibodies) C807T SNP, ITGB3 (show ITGB3 Antibodies) T1565C SNP, PECAM1 (show PECAM1 Antibodies) CTG - GTG (show GGT1 Antibodies) and SELP (show SEPP1 Antibodies) A/C polymorphisms with fetal growth restriction (FGR (show FGR Antibodies)).

  5. Study concluded that the genotype and allele frequencies of SELP (show SEPP1 Antibodies) S290N were not significant different between the acute ischemic stroke case group and the control group as well as between each subtype group and the control group

  6. High SELP (show SEPP1 Antibodies) expression is associated with Inflamed Atherosclerotic Plaque.

  7. Circulating P-selectin levels were closely associated with endocan (show ESM1 Antibodies) levels in obese children and adolescents with non-alcoholic fatty liver disease.

  8. Primary Aldosteronism is related to platelet activation, expressed as higher plasma values of soluble CD40L (show CD40LG Antibodies) and soluble P-selectin values.

  9. Immobilized P-selectin-induced calcium signaling of HL-60 cells is P-selectin concentration- and mechanical force-dependent

  10. results found that LMWF protected the renal function in diabetic nephropathy rats and alleviated inflammation through the modulation of P-selectin and inflammatory cytokines. LMWF may have therapeutic potential against diabetic nephropathy.

Horse (Equine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Despite the decrease of CD62P expression, the observed increased surface expression of CD41/61 on platelets in horses with recurrent airway obstruction may contribute to the formation of platelet aggregates in their respiratory system.

Cow (Bovine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. Five single nucleotide polymorphisms (SNPs) from different exons in selectin SELP, two in selectin SELL and one in selectin SELE (show SELE Antibodies) were taken forward to genotyping in 337 Holstein Friesian heifers using PCR-RFLP.

  2. SELP mediates the attachment of peripheral blood leukocytes to endothelium and provides novel evidence that its high polymorphism is likely to affect biological function. This may potentially influence leukocyte migration and fertility, both key to successful performance in dairy cows.

Mouse (Murine) Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP) interaction partners

  1. deletion of P-sel disrupted megakaryocyte/neutrophil interactions in spleen, reduced TGF-beta (show TGFB1 Antibodies) content, and corrected the hematopoietic stem cells distribution that in Gata1 (show GATA1 Antibodies)(low) mice, as in primary myelofibrosis patients, is abnormally expanded in spleen.

  2. The present study supported the notion that CD62P accumulation during platelet storage is involved in mediating transfusion-related acute lung injury.

  3. Holothurian glycosaminoglycan has emerged as a novel anti-cancer agent via blocking P-selectin-mediated malignant events of tumor metastasis.

  4. Data (including data from studies in transgenic mice) suggest that sequence variations limited to 1.4-kb proximal promoter region account for most differences in expression of murine Selp (show SEPP1 Antibodies) and human SELP (show SEPP1 Antibodies) genes.

  5. P-selectin has a role in endothelial progenitor cells' inhibition of platelet function

  6. Both platelet and endothelial cell P-selectin contribute to host defense during Klebsiella pneumosepsis.

  7. Platelet infiltration into solid tumors occurs through a P-selectin-dependent mechanism and promotes tumor growth.

  8. P-selectin promotes neutrophil extracellular trap (NET) formation and is a potential target for NET-related diseases.

  9. P-selectin is an important adhesion molecule (show NCAM1 Antibodies) vital for infiltration of regulatory T cells into mouse mammary tumors

  10. Administering human recombinant PTX3 (show PITX3 Antibodies) to wild-type mice induced endothelial dysfunction and increased blood pressure, an effect absent in P-selectin-deficient mice.

SELP Antigen Profile

Protein Summary

This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented.

Gene names and symbols associated with SELP

  • selectin P (Selp) antibody
  • selectin P (granule membrane protein 140kDa, antigen CD62) (SELP) antibody
  • selectin P (granule membrane protein 140kDa, antigen CD62) (Selp) antibody
  • selectin, platelet (Selp) antibody
  • CD62 antibody
  • CD62P antibody
  • GMP-140 antibody
  • GMP140 antibody
  • Grmp antibody
  • LECAM3 antibody
  • PADGEM antibody
  • PSEL antibody
  • PSELECT antibody

Protein level used designations for SELP

CD62 antigen-like family member P , GMP-140 , LECAM3 , P-selectin , PADGEM , granule membrane protein 140 , leukocyte-endothelial cell adhesion molecule 3 , platelet activation dependent granule-external membrane protein , selectin, platelet , granulocyte membrane protein , platelet alpha-granule membrane protein , CD62P antigen , cell adhesion molecule

GENE ID SPECIES
25651 Rattus norvegicus
6403 Homo sapiens
100009695 Equus caballus
443305 Ovis aries
397150 Sus scrofa
100009534 Oryctolagus cuniculus
100716162 Cavia porcellus
281486 Bos taurus
403994 Canis lupus familiaris
424364 Gallus gallus
20344 Mus musculus
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