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Selenoprotein W, 1 (SEPW1) ELISA Kits

SEPW1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Additionally we are shipping Selenoprotein W, 1 Antibodies (28) and Selenoprotein W, 1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat SEPW1 SEPW1 25545 P63301
Anti-Human SEPW1 SEPW1 6415 P63302
Anti-Mouse SEPW1 SEPW1 20364 P63300
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More ELISA Kits for Selenoprotein W, 1 Interaction Partners

Chimpanzee Selenoprotein W, 1 (SEPW1) interaction partners

  1. Selenoprotein W is conserved in human, rhesus monkey, sheep, rat, and mouse.

Human Selenoprotein W, 1 (SEPW1) interaction partners

  1. SelW may have a regulatory function in redox cell signaling by interacting with 14-3-3 protein (show YWHAE ELISA Kits).

  2. Suppression of EGFR (show EGFR ELISA Kits) ubiquitination by SEPW1 may be related to the putative increase in cancer risk associated with high selenium intakes.

  3. In response to selenium compounds, SepW1 synthesis increased at the protein and the mRNA levels.

  4. SEPW1 silencing increases MKK4 (show MAP2K4 ELISA Kits), which activates p38gamma (show MAPK12 ELISA Kits), p38delta (show MAPK1/3 ELISA Kits), and JNK2 (show MAPK9 ELISA Kits) to phosphorylate p53 (show TP53 ELISA Kits) on Ser (show SIGLEC1 ELISA Kits)-33 and cause a transient G(1) arrest.

  5. p53 (show TP53 ELISA Kits) was increased in SEPW1 silenced cells and was inversely correlated with SEPW1 mRNA in cell lines with altered SEPW1 expression.

  6. The present work shows that SEPW1 facilitates the G1 to S-phase transition by down-regulating expression of the cyclin-dependent kinase (show CDK1 ELISA Kits) inhibitor p21 (show CDKN1A ELISA Kits)

  7. The gene lacks canonical TATA and CAAT boxes, but has numerous Sp1 (show PSG1 ELISA Kits) consensus binding sites upstream of multiple transcription start sites. SEPW1 is expressed in all of the 22 tissues assayed, and shows highest expression in skeletal muscle and heart.

  8. SelW expression in the colon is highly sensitive to Se-depletion

  9. SeW is the novel molecular target of MeHg in human neuronal cells and down-regulation of this selenoenzyme by MeHg is dependent not on generation of ROS (show ROS1 ELISA Kits) but on depletion of GSH.

  10. SEPW1 mRNA levels were maximal during G1-phase, dropped after the G1/S transition and increased again after G2/M-phase.

Mouse (Murine) Selenoprotein W, 1 (SEPW1) interaction partners

  1. SelW enhances myoblast differentiation by inhibiting TAZ (show TAZ ELISA Kits) binding to 14-3-3 (show YWHAQ ELISA Kits).

  2. SelW gene was activated by the binding of MyoD (show MYOD1 ELISA Kits) to a specific E-box during early skeletal muscle differentiation.

  3. The main function of SelW in muscle cells is not in the antioxidative system.

  4. Data show that the loss of SelT (show SELT ELISA Kits) elevates expression of another selenoprotein, selenoprotein W, suggesting that SepW1 may functionally compensate for SelT (show SELT ELISA Kits).

  5. Selenoprotein W is involved in muscle growth and differentiation by protecting the developing myoblasts from oxidative stress

  6. increased in mouse brains of postnatal day 8 and 20 relative to embryonic day 15; siRNA-transfected neurons are more sensitive to the oxidative stress-induced (show SQSTM1 ELISA Kits) apoptosis

Selenoprotein W, 1 (SEPW1) Antigen Profile

Antigen Summary

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein shows highest expression in skeletal muscle and heart, and may be involved in oxidation-reduction reactions. A retroprocessed pseudogene, SEPW1P, has been identified and mapped to chromosome 1p35-34.

Gene names and symbols associated with Selenoprotein W, 1 (SEPW1) ELISA Kits

  • selenoprotein W, 1 (SEPW1) antibody
  • selenoprotein W, 1 (sepw1) antibody
  • selenoprotein W, 1 (Sepw1) antibody
  • selenoprotein W, muscle 1 (Sepw1) antibody
  • cb694 antibody
  • fe37b06 antibody
  • selW antibody
  • selw1 antibody
  • SEPW antibody
  • sepw1 antibody
  • wu:fe37b06 antibody
  • wu:fk70h03 antibody
  • zgc:109781 antibody

Protein level used designations for Selenoprotein W, 1 (SEPW1) ELISA Kits

selenoprotein W , selenoprotein W, 1 , selenoprotein W, muscle 1 , selW

GENE ID SPECIES
523694 Bos taurus
612109 Canis lupus familiaris
100050195 Equus caballus
100145402 Xenopus (Silurana) tropicalis
100286805 Pan troglodytes
100410801 Callithrix jacchus
100462742 Ciona intestinalis
100483337 Ailuropoda melanoleuca
25545 Rattus norvegicus
6415 Homo sapiens
100310814 Gallus gallus
397032 Sus scrofa
101119329 Ovis aries
718370 Macaca mulatta
100174175 Pongo abelii
352915 Danio rerio
20364 Mus musculus
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