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Selenoprotein X, 1 Proteins (SEPX1)

SEPX1 encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. Additionally we are shipping Selenoprotein X, 1 Antibodies (17) and Selenoprotein X, 1 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEPX1 51734 Q9NZV6
SEPX1 27361 Q9JLC3
SEPX1 685059 Q52KJ8
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Top Selenoprotein X, 1 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$809.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
$2,225.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,225.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,225.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,225.67
Details

SEPX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

Top referenced Selenoprotein X, 1 Proteins

  1. Human SEPX1 Protein expressed in Escherichia coli (E. coli) - ABIN667227 : Liang, Fomenko, Hua, Kaya, Gladyshev: Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing. in PLoS ONE 2010 (PubMed)
    Show all 2 references for ABIN667227

More Proteins for Selenoprotein X, 1 (SEPX1) Interaction Partners

Human Selenoprotein X, 1 (SEPX1) interaction partners

  1. Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress.

  2. MsrB1 protected human lens epithelial cells against the peroxynitrite-induced F-actin disruption

  3. MsrB1 plays important roles in protecting HLE (show ELANE Proteins) cell mitochondria against oxidative damage and inhibits oxidative stress-induced (show SQSTM1 Proteins) apoptosis in diabetic cataracts by scavenging ROS (show ROS1 Proteins).

  4. The results demonstrate that in human lens epithelial cells MsrB1 may play important roles in regulating redox balance and mitigating endoplasmic reticulum stress.

  5. The studies in mouse show that MsrB (show MSRB2 Proteins) is a selenoprotein that exhibits high specificity for reduction of the R forms of free and protein-bound methionine sulfoxide.

Mouse (Murine) Selenoprotein X, 1 (SEPX1) interaction partners

  1. study identified the regulatory role of MsrB1 as a Mical antagonist in orchestrating actin dynamics and macrophage function

  2. MsrB1/Trx (show TXN Proteins) complex was studied in attempt to understand MsrB1 reduction mechanism. Using NMR data, molecular mechanics, protein docking & molecular dynamics simulations, found that intermediate MsrB1/Trx (show TXN Proteins) complex is stabilized by interprotein beta-layer.

  3. Analyses of fruit flies that do not express selenoproteins or express the mouse selenoprotein, methionine sulfoxide reductase B1, reveal a role of selenoproteins in stress resistance.

  4. Insights into function, catalytic mechanism, and fold evolution of selenoprotein methionine sulfoxide reductase B1 through structural analysis.

  5. Study characterized unexpected diversity of protein and mRNA forms of mammalian selenoprotein MsrB1.

  6. MsrB1 recovers TRPM6 (show TRPM6 Proteins) channel activity by reducing the oxidation of Met(1755) and could, thereby, function as a modulator of TRPM6 (show TRPM6 Proteins) during oxidative stress.

  7. Data show that methionine sulfoxide reductase (Msr (show MSR1 Proteins))B1, but not MsrA (show MSR1 Proteins), is the major methionine sulfoxide reductase in liver of mice and it is among the proteins that are most easily regulated by dietary selenium.

  8. The chemical shift index for MsrB1 indicates that the beta-sheets are the main element for the protein secondary structure.

Selenoprotein X, 1 (SEPX1) Protein Profile

Protein Summary

This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein belongs to the methionine sulfoxide reductase (Msr) protein family which includes repair enzymes that reduce oxidized methionine residues in proteins. The protein encoded by this gene is expressed in a variety of adult and fetal tissues and localizes to the cell nucleus and cytosol.

Gene names and symbols associated with Selenoprotein X, 1 Proteins (SEPX1)

  • methionine sulfoxide reductase B1a (msrb1a)
  • selenoprotein X, 1 (SEPX1)
  • selenoprotein X, 1 (sepx1)
  • selenoprotein X, 1 (Sepx1)
  • methionine sulfoxide reductase B1 (MSRB1)
  • methionine sulfoxide reductase B1 (Msrb1)
  • methionine sulfoxide reductase B1 (SEPX1)
  • cb687 protein
  • D17Wsu82e protein
  • DKFZp469G2418 protein
  • MsrB protein
  • MSRB1 protein
  • MsrB1-A protein
  • SelR protein
  • selX protein
  • SelX-A protein
  • Sepr protein
  • Sepx1 protein
  • sepx1a protein
  • wu:fa03e09 protein

Protein level used designations for Selenoprotein X, 1 Proteins (SEPX1)

methionine-R-sulfoxide reductase B1 , methionine-R-sulfoxide reductase B1-A , msrB1 , selenoprotein X, 1 , selenoprotein X, 1a , selenoprotein X-A , selenoprotein R , selenoprotein X 1 , selX , Methionine-R-sulfoxide reductase B1

GENE ID SPECIES
352916 Danio rerio
416540 Gallus gallus
448399 Xenopus (Silurana) tropicalis
611032 Canis lupus familiaris
693358 Macaca mulatta
746697 Pan troglodytes
100068001 Equus caballus
100377187 Saccoglossus kowalevskii
51734 Homo sapiens
27361 Mus musculus
685059 Rattus norvegicus
100037965 Sus scrofa
100173105 Pongo abelii
618441 Bos taurus
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