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Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins (SEMA3A)

SEMA3A is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. Additionally we are shipping Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Antibodies (48) and Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Kits (33) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEMA3A 10371 Q14563
SEMA3A 20346 O08665
SEMA3A 29751 Q63548
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Top Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins at antibodies-online.com

Showing 10 out of 16 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Mouse Fc Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_CHO Cells Human Fc Tag   50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$633.60
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$753.50
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$823.90
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,202.00
Details

SEMA3A Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A Proteins

  1. Mouse (Murine) SEMA3A Protein expressed in Human Cells - ABIN2008081 : Chadborn, Ahmed, Holt, Prinjha, Dunn, Jones, Eickholt: PTEN couples Sema3A signalling to growth cone collapse. in Journal of cell science 2006 (PubMed)
    Show all 3 references for ABIN2008081

  2. Human SEMA3A Protein expressed in Human Cells - ABIN2003354 : Schmidt, Strittmatter: The CRMP family of proteins and their role in Sema3A signaling. in Advances in experimental medicine and biology 2007 (PubMed)
    Show all 2 references for ABIN2003354

More Proteins for Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) interaction partners

  1. Semaphorin-3a, neuropilin-1 (show NRP1 Proteins) and plexin-A1 (show PLXNA1 Proteins) are axonal guidance molecules that have been recently implicated in regulating bone metabolism.

  2. Sema3A and sema7A (show SEMA7A Proteins) expression correlated with the inflammatory activity of the multiple sclerosis (MS) lesions, suggesting their involvement in the immunological process that takes place in MS.

  3. Sema3A expression is low in systemic sclerosis serum and more specifically on regulatory T cells.

  4. Findings show the involvement of amphiregulin (show AREG Proteins) and semaphorin-3A in the improvement of skin innervations and penetration of nerve fibers into the epidermis.

  5. LL-37 induces SeMA3A expression in epidermal keratinocytes. Possible therapy for pruritus in atopic dermatitis.

  6. Vital roles for semaphorin signaling in vascular patterning and cardiac morphogenesis have been demonstrated, and impaired semaphorin signaling has been associated with various human cardiovascular disorders.

  7. our data suggest that MCF-7 cell-derived Sema (show SEMA3B Proteins) 3A plays a causative role in osteoblastic bone metastases progression by stimulating osteoblastic differentiation.

  8. Increased urinary SEMA3A is independently associated with CKD in both diabetic and non diabetic hypertensive patients.

  9. Despite limited research in this field, our aim is to promote further understanding of the function of Sema3A in the skeletal system.

  10. Genetic risk for Hirschsprung disease in individuals of European ancestry can only be detected at RET (show RET Proteins) (rs2435357 and rs2506030) and at SEMA3 (rs11766001), but not at NRG1 (show NRG1 Proteins).

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) interaction partners

  1. These findings indicate that endothelial cell-derived Sema3A exerts repelling functions on VEGF-A (show VEGFA Proteins)-induced tip cell filopodia and that a lack of this signaling cannot be rescued by paracrine sources of Sema3A.

  2. Data suggest that sema3A is involved in the pathogenesis of experimental autoimmune encephalomyelitis, in the modulation of the immune response and in the neurodegeneration that take place in the CNS.

  3. these studies demonstrated that Sema3A is a key mediator of cerebrovascular permeability and contributes to brain damage caused by cerebral ischemia.

  4. Diabetes induced sema3A excretion in urine. Increased semaphorin 3A was associated with severity of albuminuria. Seme3A-mediated diabetes induced glomerulosclerosis.

  5. These findings indicate that excess sema3a promotes severe diabetic nephropathy and identifies novel potential therapeutic targets for diabetic nephropathy.

  6. interleukin-4 (show IL4 Proteins) and tumor necrosis factor-alpha (show TNF Proteins) stimulation increases epidermal innervation and suppresses semaphorin 3A

  7. The Sema3A/Npn1 (show NRP1 Proteins) pathway participates to the parcellation of the visual neocortex in both the mouse.

  8. Data suggest that loss of semaphorin-3A (Sema3A)-neuropilin 1 (Npn1 (show NRP1 Proteins)) signaling is not the only cause for the developmental deficits.

  9. Sema3A is an essential, locally produced chemorepellant, which by creating mesenchymal exclusion areas, regulates the timing and patterning of the dental nerves during the development of incisor tooth germ.

  10. Sema3A exacerbates acute kidney injury via promoting inflammation and epithelial cell apoptosis.

Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3A (SEMA3A) Protein Profile

Protein Summary

This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.

Gene names and symbols associated with SEMA3A

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (SEMA3E)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (sema3e)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (LOC100230255)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (SEMA3A)
  • Sema-3a (Sema-3a)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (Sema3a)
  • semaphorin-3A-like (LOC100357227)
  • COLL-1 protein
  • COLL1 protein
  • Dsema3a protein
  • fj37c11 protein
  • HH16 protein
  • Hsema-I protein
  • Hsema-III protein
  • SEMA1 protein
  • Sema3A protein
  • Semad protein
  • SEMAIII protein
  • SEMAL protein
  • SemD protein
  • si:ch211-120m13.2 protein
  • wu:fj37c11 protein

Protein level used designations for SEMA3A

semaphorin 3E , semaphorin-3E , sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A , semaphorin 3A , semaphorin-3A-like , collapsin 1 , semaphorin D , semaphorin III , semaphorin L , semaphorin-3A , collapsin-1 , sema D , sema III , semaphorin-D , Semaphorin 3a , sema domain, immunoglobulin domain (Ig), short basic domain, sec , collapsin

GENE ID SPECIES
472429 Pan troglodytes
565658 Danio rerio
100230255 Taeniopygia guttata
483386 Canis lupus familiaris
745878 Pan troglodytes
5657999 Drosophila melanogaster
100458068 Pongo abelii
100587973 Nomascus leucogenys
10371 Homo sapiens
20346 Mus musculus
29751 Rattus norvegicus
395825 Gallus gallus
100731288 Cavia porcellus
100357227 Oryctolagus cuniculus
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