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The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. Additionally we are shipping SEMA3B Antibodies (32) and SEMA3B Kits (17) and many more products for this protein.
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By upregulating p53 (show TP53 Proteins) and p21 (show CDKN1A Proteins) expression and inhibiting Akt (show AKT1 Proteins) (Ser473) phosphorylation, SEMA3B could induce cell cycle arrest at G1/S phase.
As the clinical pathological glioma grade increased, SEMA3B expression decreased.
Maternal SEMA 3B level increased in preeclampsia before the onset of manifestations, indicating that SEMA 3B plays a role in the pathogenesis of preeclampsia
Aberrant expression and methylation of SEMA3B could be suggested as markers of lung and renal cancer progression.
although plexin-A4 (show PLXNA4 Proteins) overexpression restored Sema3A (show SEMA3A Proteins) signaling in plexin-A1 (show PLXNA1 Proteins)-silenced cells, it failed to restore Sema3B signaling in plexin-A2 (show Plxna2 Proteins)-silenced cells.
SEMA3B mRNA and protein is not altered in severe early onset preeclamptic placentas.
CpG methylation of SEMA3B epigenetically regulates SEMA3B expression during development of gastric cancer.
The transcriptional activity of RHOA (show RHOA Proteins), SEMA3B, and CKAP2 (show CKAP2 Proteins) genes was assessed in blood samples of leukaemia patients and healthy donors.
Three candidate tumor-suppressor genes, SEMA3B, AXUD1 (show CSRNP1 Proteins) and GNAT1 (show GNAT1 Proteins) may be involved in oral squamous cell carcinoma.
Loss of Sema3B expression is associated with biochemical recurrence of patients with low- and intermediate-risk prostate cancer.
Semaphorin3B may contribute to impaired bone formation by elevated TNF-alpha (show TNF Proteins) in estrogen-deficiency-induced osteoporosis.
Dual functional activity of semaphorin 3B is required for positioning the anterior commissure.
The semaphorin/collapsin family of molecules plays a critical role in the guidance of growth cones during neuronal development. The secreted protein encoded by this gene family member is important in axonal guidance and has been shown to act as a tumor suppressor by inducing apoptosis.
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
, semaphorin 3B
, sema A(V)
, sema V
, semaphorin A
, sema A