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Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C Proteins (SEMA3C)

Binds to plexin family members and plays an important role in the regulation of developmental processes. Additionally we are shipping SEMA3C Antibodies (43) and SEMA3C Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SEMA3C 10512 Q99985
SEMA3C 20348 Q62181
Rat SEMA3C SEMA3C 296787  
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Top SEMA3C Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$269.50
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 11 to 13 Days
$545.60
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$731.71
Details
HOST_Human Human Un-conjugated   10 μg Log in to see 11 to 14 Days
$460.85
Details

SEMA3C Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. Data show significant increases in semaphorin3C, 3D and their receptor neuropilin-2 (show NRP2 Proteins) in degenerate samples which were shown to contain nerves and blood vessels, compared to non-degenerate samples without nerves and blood vessels.

  2. Increased levels of Sema3C protein may be associated with the progression of glioma tumor and have potential as a prognostic marker for outcome of glioma patients.

  3. SEMA3C expression increased in the transition from normal to malignant breast lesions and correlated with microvessel density and tumour grade and is differentially regulated in the development of breast versus oral neoplasia.

  4. Glioma stem cells preferentially secrete Sema3C and coordinately express PlexinA2/D1 receptors to activate Rac1/nuclear factor (NF)-kB signaling.

  5. p65 (show GORASP1 Proteins)-Sema3C, but not FR-sema3C, rendered A549 lung cancer cells resistant to serum deprivation, suggesting that previously reported protumorigenic activities of sema3C may be due to p65 (show GORASP1 Proteins)-Sema3C produced by tumor cells

  6. Functional loss of semaphorin 3C and/or semaphorin 3D (show SEMA3D Proteins) and their epistatic interaction with ret (show RET Proteins) are critical to Hirschsprung disease liability.

  7. SEMA3C is a novel adipokine regulated by weight changes.

  8. Capillary-like tubular formation was reduced by the addition of culture media of sema3C miRNA cells.

  9. cleavage of semaphorin 3C induced by ADAMTS1 (show ADAMTS1 Proteins) promotes the migration of breast cancer cells, indicating that the co-expression of these molecules in tumors may contribute to the metastatic program

  10. human glioma cells express class 3 semaphorins and receptors for soluble and membrane-bound semaphorins, suggesting a possible role of the semaphorin/neuropilin (show NRP1 Proteins) system in the interactions of human malignant glioma with the nervous and immune systems.

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3C (SEMA3C) interaction partners

  1. analyzed a complementary set of ligand-specific and tissue-specific mutants to show that neural crest-derived SEMA3C activates NRP1 (show NRP1 Proteins) in the cardiac outflow tract endothelium

  2. Sema3A (show SEMA3A Proteins) overrides the effects of Sema3C in cortical axons exposed to defined mixtures of these opposing guidance cues in vitro

  3. No changes were observed in the binding of Sema3C to Nrp1 (show NRP1 Proteins)-silenced B16(F10 (show F10 Proteins)) cells, nor in its chemorepellent activity.

  4. Data suggest that the formation and synaptic specificity of the GABAergic septohippocampal pathway relies on robust molecular mechanisms, independent of semaphorin 3C.

  5. the guidance factor Semaphorin 3C, which is expressed by corpus callosum neurons, acts through the neuropilin 1 (show NRP1 Proteins) receptor to orient axons crossing through the corpus callosum.

  6. Secreted sema3C favors cell survival and neuritogenesis of cultured cerebellar granule neurons

  7. GATA-6 (show GATA6 Proteins) regulates semaphorin 3C and is required in cardiac neural crest for cardiovascular morphogenesis

  8. sema (show SEMA3B Proteins) 3C promotes glomerular endothelial cell proliferation, adhesion, directional migration, and tube formation in vitro by stimulating integrin phosphorylation and VEGF120 (show VEGFA Proteins) secretion

  9. Npn1 (show NRP1 Proteins)-dependent morphogenesis is mediated by Sema3A (show SEMA3A Proteins) and Sema3C in an additive manner.

  10. The endocytic pathway of neuropilin(Nrp)1 (show NRP1 Proteins) depends on its ligand: sema3C induces lipid raft-dependent endocytosis.

SEMA3C Protein Profile

Protein Summary

Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).

Gene names and symbols associated with SEMA3C

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (Sema3c)
  • 1110036B02Rik protein
  • Semae protein
  • SemE protein

Protein level used designations for SEMA3C

sema E , semaphorin E , semaphorin-3C , semaphorin-E , COLL-3 , collapsin-3

GENE ID SPECIES
100054706 Equus caballus
10512 Homo sapiens
20348 Mus musculus
374090 Gallus gallus
512660 Bos taurus
296787 Rattus norvegicus
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