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Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F Proteins (SEMA3F)

The semaphorins are a family of proteins that are involved in signaling. Additionally we are shipping Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F Antibodies (34) and Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SEMA3F SEMA3F 315996  
SEMA3F 6405 Q13275
SEMA3F 20350 O88632
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Top Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$633.60
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HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$810.39
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SEMA3F Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

More Proteins for Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F) Interaction Partners

Human Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F) interaction partners

  1. SEMA3F was downregulated in colorectal cancer tissues as compared to matched adjacent non-tumor tissues

  2. A new SEMA3F transcript is expressed in all breast cell lines and breast cancer biopsies, and is translated into a new semaphorin 3F isoform.

  3. SEMA3F-NRP2 (show NELL2 Proteins) interactions inhibit intracellular PI-3K activity, mTORC2 (show CRTC2 Proteins)-dependent signaling, RhoA (show RHOA Proteins) activity and cytoskeletal stress fiber formation.

  4. Data indicate that semaphorin 3F (SEMA3F) and its receptor neuropilin-2 (NRP2 (show NRP2 Proteins)) are expressed in the thymus.

  5. SEMA3F functions as a suppressor of colorectal cancer metastasis by down-regulating the ASCL2 (show ASCL2 Proteins)-CXCR4 (show CXCR4 Proteins) signaling axis.

  6. SEMA3F may represent an antilymphangiogenic metastasis suppressor gene widely lost during cancer progression, hence serving as a prognostic biomarker and an attractive target for therapeutic intervention to halt metastasis.

  7. Infantile hemangioma-derived stem cells and endothelial cells are inhibited by SEMA3E (show SEMA3E Proteins) and SEMA3F.

  8. Our findings demonstrate the ability of SEMA3F to inhibit the stemness of human CRC cells by suppressing Rac1 activation, which suggests a novel therapeutic approach for colorectal cancer

  9. Data suggest that SEMA3F C-terminal domain exhibits high-affinity binding of neuropilin-1 (NRP1 (show NRP1 Proteins); thus inhibiting binding of vascular endothelial growth factor A (show VEGFA Proteins) to NRP1 (show NELL1 Proteins)); this interaction may be involved in anti-angiogenic activity of SEMA3F.

  10. A functional role for Semaphorin 3F in the outer retina where it acts as a vasorepulsive cue to maintain physiologic avascularity.

Mouse (Murine) Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F) interaction partners

  1. Sema3F plays important roles in the development of neuronal circuitry underlying the regulation of some aspects of anxiety and fear responses.

  2. The authors demonstrate that expression of Semaphorin-3F in the outer hair cell region inhibits type I spiral ganglion neuron process extension by activating Neuropilin-2 (show NRP2 Proteins) receptors expressed on spiral ganglion neurons.

  3. the embryonically developed wiring deficits in Sema3F mutants persist until adulthood

  4. Sema4A (show Sema4a Proteins) promotes Th1 (show HAND1 Proteins) and Th17 differentiation and increases adhesive activation of T cells to endothelial cells, even in the presence of IFN-beta (show IFNB1 Proteins).

  5. In a growth cone collapse assay, mouse embryonic stem cell-derived spinal motor neurons respond to ephrin-A5 (show EFNA5 Proteins), semaphorin(Sema (show SEMA3B Proteins))3f, and Sema3a (show SEMA3A Proteins) in a concentration-dependent manner.

  6. Sema3F is secreted by early-arriving axons of olfactory sensory neurons and is deposited at the anterodorsal olfactory bulb to repel Nrp2 (show NRP2 Proteins)-positive axons that arrive later.

  7. These data suggest that Sema3F plays a relatively restricted, if any, role in its receptor expression and postnatal development of the somatosensory cortex, the cerebellum, and the main olfactory system.

  8. Sema3F is the principal ligand for Npn-2 (show NRP2 Proteins)-mediated axon guidance events in vivo and is a critical determinant of limbic and peripheral nervous system circuitry

  9. Sema3F alternatively spliced isoforms share common axonal chemorepulsive properties and binding to neuropilin (show NRP1 Proteins) receptors, and are found to regulate endothelial cell morphology by remodeling lamellipodial protrusions.

  10. Sema (show SEMA3B Proteins) 3A and 3F, but not Sema (show SEMA3B Proteins) 3C or 3E, induce chemorepulsion of septal axons.

Sema Domain, Immunoglobulin Domain (Ig), Short Basic Domain, Secreted, (Semaphorin) 3F (SEMA3F) Protein Profile

Protein Summary

The semaphorins are a family of proteins that are involved in signaling. All the family members have a secretion signal, a 500-amino acid sema domain, and 16 conserved cysteine residues (Kolodkin et al., 1993

Gene names and symbols associated with SEMA3F

  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (SEMA3F)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (sema3f)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (SEMA3C)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3 F (Sema3f)
  • sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (Sema3f)
  • MGC79683 protein
  • SEMA-IV protein
  • SEMA3F protein
  • Sema4 protein
  • SemaIV protein
  • Semak protein
  • semaphorin-3F protein

Protein level used designations for SEMA3F

semaphorin-3F , sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F , sema iv , semaphorin-3C , semaphorin 3F , semaphorin IV , sema III/F , sema IV , sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 3F , semaphorin III/F

GENE ID SPECIES
374109 Gallus gallus
448771 Xenopus (Silurana) tropicalis
460387 Pan troglodytes
484763 Canis lupus familiaris
496575 Xenopus (Silurana) tropicalis
531141 Bos taurus
703995 Macaca mulatta
708633 Macaca mulatta
100062215 Equus caballus
100153225 Sus scrofa
100158345 Xenopus laevis
100407382 Callithrix jacchus
100588221 Nomascus leucogenys
315996 Rattus norvegicus
6405 Homo sapiens
20350 Mus musculus
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