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Has chemorepulsive activities for sympathetic axons. Additionally we are shipping SEMA3G Antibodies (31) and SEMA3G Kits (6) and many more products for this protein.
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analysis of developmental expression of sema3G in zebrafish
Results identify Sema3g as one of the downstream effectors of PPAR-gamma (show PPARG Proteins), which is centrally involved in regulating endothelial cell migration.
overexpressed SEMA3G inhibited the migratory and invasive behavior of U251MG cancer cells
Identify Sema3G as a primarily endothelial cell-expressed class 3 semaphorin that controls endothelial and smooth muscle cell functions in autocrine and paracrine manners.
In gliomas, SEMA3B (show SEMA3B Proteins), SEMA3G and NRP2 (show NELL2 Proteins) expressions were related to prolonged survival
Sema3G inhibits tumor progression from MDA-MB-435 but not from MDA-MB-231 cancer cells. It inhibits tumor angiogenesis in MDA-MB-231 cells.
In adulthood, Sema3G is mainly expressed in the lung and kidney, and a little in the brain. We also found that Sema3G binds Neuropilin-2 (show NRP2 Proteins), but not Neuropilin-1 (show NRP1 Proteins), and induces the repulsion of sympathetic axons.
Has chemorepulsive activities for sympathetic axons. Ligand of NRP2.
class 3 secreted semaphorin
, semaphorin 8
, semaphorin 3G
, sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
, semaphorin sem2
, Semaphorin 3G