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Sema4a Proteins

(Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4A (Sema4a))

This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010].

recommended

Sema4a Protein (AA 1-761) (GST tag) (ABIN1319469)

Sema4a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

Sema4a Protein (AA 33-132) (GST tag) (ABIN1319471)

Sema4a Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA

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recommended

Sema4a Protein (His tag) (ABIN7320641)

Sema4a Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE

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Sema4a Proteins by Grade

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Sema4a Proteins by Origin

Find Sema4a Proteins for a variety of species such as anti-Human Sema4a, anti-Mouse Sema4a. The species listed below are among those available. Click on a link to go to the corresponding products.

Sema4a Proteins by Source

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Sema4a Proteins by Protein Type

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Sema4a Proteins by Application

Find Sema4a Proteins validated for a specific application such as WB, ELISA, SDS, Crys. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Sema4a Proteins by Biological Activity

Find Sema4a Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular Sema4a Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

Sema4a Protein (AA 1-761) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319469

Quantity 10 μg

Datasheet Datasheet

Sema4a Protein (AA 33-132) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1319471

Quantity 10 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN7320641

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (AA 33-683) (His tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3095447

Quantity 1 mg

Datasheet Datasheet

Sema4a Protein (AA 33-682) (His tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3135514

Quantity 1 mg

Datasheet Datasheet

Sema4a Protein (AA 33-761) (rho-1D4 tag)

Reactivity Human

Source Insect Cells

Validations

Cat. No. ABIN3118104

Quantity 1 mg

Datasheet Datasheet

Sema4a Protein (AA 33-760) (rho-1D4 tag)

Reactivity Mouse

Source Insect Cells

Validations

Cat. No. ABIN3135515

Quantity 1 mg

Datasheet Datasheet

Sema4a Protein (AA 33-683) (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2181737

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Fc Tag,His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7520489

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (AA 33-682) (His tag)

Reactivity Mouse

Source Human Cells

Validations

Cat. No. ABIN4371022

Quantity 50 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7386176

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (AA 1-676) (Fc Tag)

Reactivity Mouse

Source CHO Cells

Validations

Cat. No. ABIN6253441

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (His tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317489

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Fc Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN7317490

Quantity 100 μg

Datasheet Datasheet

Sema4a Protein (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2731626

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our Sema4a Proteins

Chiou, Lucassen, Sather, Kallianpur, Connor: "Semaphorin4A and H-ferritin utilize Tim-1 on human oligodendrocytes: A novel neuro-immune axis." in: Glia, Vol. 66, Issue 7, pp. 1317-1330, (2018) (PubMed).

Peng, Gao, Chong, Liu, Zhang: "Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor." in: Journal of biosciences, Vol. 40, Issue 5, pp. 855-62, (2015) (PubMed).

Mogie, Shanks, Nkyimbeng-Takwi, Smith, Davila, Lipsky, DeTolla, Keegan, Chapoval: "Neuroimmune semaphorin 4A as a drug and drug target for asthma." in: International immunopharmacology, Vol. 17, Issue 3, pp. 568-75, (2013) (PubMed).

Aliases for Sema4a Proteins

semaphorin 4A (SEMA4A) Proteins
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (sema4a) Proteins
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a) Proteins
semaphorin 4A (Sema4a) Proteins
AI132332 Proteins
CORD10 Proteins
RP35 Proteins
SEMA4A Proteins
SEMAB Proteins
Semab Proteins
SEMB Proteins
SemB Proteins

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Sema4a Proteins by Grade

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Popular Sema4a Proteins

Latest Publications for our Sema4a Proteins

Aliases for Sema4a Proteins

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