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Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.. Additionally we are shipping Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B Proteins (19) and Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4B Kits (5) and many more products for this protein.
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Cow (Bovine) Polyclonal SEMA4B Primary Antibody for WB - ABIN2773943
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
SEMA4B may induce FoxO1 (show FOXO1 Antibodies) nuclear retention through suppressing PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1 (show FOXO1 Antibodies), p21 (show CDKN1A Antibodies).
Decrease in SEMA4b levels are associated with metastasis of non-small cell lung cancer.
showed that HIF-1alpha (show HIF1A Antibodies) recognized a hypoxia-responsive element (HRE) of SEMA4B gene, which is required for HIF-1 (show HIF1A Antibodies)-repressed SEMA4B expression
Sema4B negatively regulates basophil-mediated T helper type (Th)2 cell and humoral memory responses.
Sema4B co-localizes with PSD-95 (show DLG4 Antibodies) at synaptic contacts between cultured hippocampal neurons.
Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4B
, sema C
, semaphorin 4B