You are viewing an incomplete version of our website. Please click to reload the website as full version.

Senataxin Proteins (SETX)

SETX encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. Additionally we are shipping Senataxin Antibodies (31) and Senataxin Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SETX 23064 Q7Z333
Mouse SETX SETX 269254 A2AKX3
Rat SETX SETX 362096  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Senataxin Proteins at antibodies-online.com

Showing 2 out of 2 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SETX Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

More Proteins for Senataxin (SETX) Interaction Partners

Human Senataxin (SETX) interaction partners

  1. The role of senataxin in regulating gene expression on a genome-wide scale in Ataxia (show USP14 Proteins) oculomotor apraxia 2 neurons is described.

  2. these data indicate a potentially causal link among inborn errors in SETX, susceptibility to infection and the development of neurologic disorders.

  3. AOA2 with myoclonus associated with mutations in SETX and AFG3L2 (show AFG3L2 Proteins)

  4. BRCA1/SETX complexes support a DNA repair mechanism that addresses R-loop-based DNA damage at transcriptional pause sites.

  5. Results identify novel genes related to senataxin function in normal and disease states.

  6. genetic variations in the senataxin gene may contribute to Alzheimer's disease pathogenesis in the Taiwanese Han population.

  7. Protein interaction analysis of senataxin and the ALS4 L389S mutant yields insights into senataxin post-translational modification and uncovers mutant-specific binding with a brain cytoplasmic RNA-encoded peptide.

  8. Description of a new SETX gene mutation, which when combined with a recognized SETX mutation results in ataxia (show USP14 Proteins) with oculomotor apraxia type 2.

  9. This study report a Japanese SCAR1/AOA2 family with a homozygous nonsense mutation (p.Q1441X) of SETX that was identified by exome sequencing

  10. SETX mutations are a frequent genetic cause of juvenile and adult onset cerebellar ataxia (show USP14 Proteins) with neuropathy and elevated serum alpha-fetoprotein (show AFP Proteins).

Mouse (Murine) Senataxin (SETX) interaction partners

  1. Results identify novel genes related to senataxin function in normal and disease states.

  2. These data support key roles for senataxin in coordinating meiotic crossing-over with transcription and in gene silencing to protect the integrity of the genome.

Senataxin (SETX) Protein Profile

Protein Summary

This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4).

Gene names and symbols associated with Senataxin Proteins (SETX)

  • senataxin (SETX)
  • senataxin (setx)
  • senataxin (Setx)
  • A130090N03 protein
  • A930037J23Rik protein
  • Als4 protein
  • AOA2 protein
  • AW060766 protein
  • bA479K20.2 protein
  • mKIAA0625 protein
  • RGD1565575 protein
  • SCAR1 protein
  • Sen1 protein
  • SETX protein
  • wu:fj92h09 protein

Protein level used designations for Senataxin Proteins (SETX)

senataxin , amyotrophic lateral sclerosis 4 , probable helicase senataxin-like , SEN1 homolog , amyotrophic lateral sclerosis 4 protein , probable helicase senataxin , amyotrophic lateral sclerosis 4 homolog , amyotrophic lateral sclerosis 4 protein homolog , DEAxQ-box helicase , tRNA splicing endonuclease regulator 1

GENE ID SPECIES
100066679 Equus caballus
417170 Gallus gallus
464815 Pan troglodytes
562474 Danio rerio
100090737 Ornithorhynchus anatinus
100145435 Xenopus (Silurana) tropicalis
100405920 Callithrix jacchus
100445729 Pongo abelii
100468613 Ailuropoda melanoleuca
100542448 Meleagris gallopavo
23064 Homo sapiens
269254 Mus musculus
362096 Rattus norvegicus
480691 Canis lupus familiaris
534284 Bos taurus
Selected quality suppliers for Senataxin Proteins (SETX)
Did you look for something else?