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anti-Septin 7 (SEPT7) Antibodies

SEPT7 encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. Additionally we are shipping Septin 7 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SEPT7 989 Q16181
SEPT7 235072 O55131
SEPT7 64551 Q9WVC0
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Top anti-Septin 7 Antibodies at antibodies-online.com

Showing 10 out of 78 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN308440 (0.5µg/ml) staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa/HuvEc/MCF-7 cells, using SEPT7 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: MOLT4 , 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human gastric cancer, using 39331, antibody at 1:100 dilution. WB Image Sample(30 μg of whole cell lysate) A:HeLa S3, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Cow Rabbit Un-conjugated IC, IF, IP, IHC, WB Immunofluorescent analysis of Septin 7 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Septin 7 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti CDC10/Septin 7 Polyclonal Antibody, Unconjugated (ABIN873015) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC, WB   100 μg Log in to see 8 to 10 Days
$1,277.83
Details
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 14 Days
$527.15
Details

SEPT7 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Septin 7 Antibodies

  1. Human Polyclonal SEPT7 Primary Antibody for ELISA, WB - ABIN308440 : Kremer, Adang, Macara: Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. in Cell 2007 (PubMed)

  2. Human Polyclonal SEPT7 Primary Antibody for ELISA, WB - ABIN1535328 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against Septin 7 Interaction Partners

Xenopus laevis Septin 7 (SEPT7) interaction partners

  1. study identified control of septin (show SEPT6 Antibodies) localization by the planar cell polarity (PCP (show PRCP Antibodies)) protein Fritz (show WDPCP Antibodies) as a crucial control point for both collective cell movement and ciliogenesis in embryos

Human Septin 7 (SEPT7) interaction partners

  1. Septin6 and Septin7 GTP binding proteins regulate AP-3- and ESCRT-dependent multivesicular body biogenesis

  2. Significantly lower SEPT7 expression in encapsulated follicular variant of papillary thyroid carcinoma may be a sign of different molecular signature in this type of tissue.

  3. In response to Candida albicans infection, SEPT7 forms a complex with endothelial cell N-cadherin (show CDH2 Antibodies), is required for normal accumulation of N-cadherin (show CDH2 Antibodies) around hyphae, and is necessary for maximal fungal endocytosis.

  4. SEPT2 (show SEPT2 Antibodies) forms a 1:1:1 complex with SEPT7 and SEPT9 (show SEPT9 Antibodies).

  5. Overexpression of the yeast septin7 ortholog CDC10 also conferred resistance to the negative effects of copper as well as protecting cells from the overexpression of Bax (show BAX Antibodies).

  6. miR (show MLXIP Antibodies)-30a-5p is a bona fide negative regulator of SEPT7 and the oncogenic activity of miR (show MLXIP Antibodies)-30a-5p in human gliomas is at least in part through the repression of SEPT7

  7. Myeloid K562 cells express three SEPT9 (show SEPT9 Antibodies) isoforms, all of which have an equal propensity to hetero-oligomerize with SEPT7-containing hexamers to generate octameric heteromers.

  8. Mutagenic analyses revealed that mutation of a potential phosphorylation site in SEPT7 (Y318) regulates the interaction with other septins.

  9. the purification, crystallization and structure for the GTP-binding (show RND2 Antibodies) domain of human septin 7

  10. Sept7 occupies the ends of hexameric building blocks which assemble into non-polarised filaments.

Horse (Equine) Septin 7 (SEPT7) interaction partners

  1. These findings point to a possible pathogenetic role of septin 7 in Equine recurrent uveitis.

Cow (Bovine) Septin 7 (SEPT7) interaction partners

  1. a SNP in the CDC10 gene was associated with growth-related traits in Japanese Black beef cattle

Mouse (Murine) Septin 7 (SEPT7) interaction partners

  1. Sept7-deficient T cells failed to complete cytokinesis when prompted by pharmacological activation or cytokines. In contrast, cell division was not dependent on sept7 when cell-cell contacts, such as those with antigen-presenting cells, provided a niche.

  2. We identified stathmin (show STMN1 Antibodies) as a key molecule aiding in septin (show SEPT6 Antibodies)-independent cytokinesis, demonstrated that stathmin (show STMN1 Antibodies) supplementation is sufficient to override cytokinesis failure in SEPT7-null fibroblasts

  3. Sept7 provides a physical scaffold for HDAC6 (show HDAC6 Antibodies) to achieve efficient microtubule deacetylation, thereby negatively regulating microtubule stability to an optimal level for neuritogenesis.

  4. Septin 7 may regulate meiotic cell cycle progression by affecting microtubule cytoskeletal dynamics in mouse oocytes.

  5. Report SEPT4 (show SEPT4 Antibodies)/5/7 expression in mouse cochlea and roles in auditory function.

  6. performed large-scale interaction screens to understand the neuronal functions of the ERK3 (show RYK Antibodies)/MK5 (show MAPKAPK5 Antibodies) pathway and identified septin7 (Sept7) as a novel interacting partner of ERK3 (show RYK Antibodies)

  7. In Sept9 (show SEPT9 Antibodies) knockout cells, long septin (show SEPT6 Antibodies) filaments stained for Sept7 disappeared. Instead, staining was found in short, often curved filaments and rings. Furthermore, Sept7 was no longer localized to the mitotic spindle

  8. SEPT7 is involved in the regulation of subcellular-compartment formation during spermiogenesis in the mouse.

Septin 7 (SEPT7) Antigen Profile

Protein Summary

This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19.

Gene names and symbols associated with anti-Septin 7 (SEPT7) Antibodies

  • septin 7a (sept7a) antibody
  • septin 7 (SEPT7) antibody
  • septin 7 (sept7) antibody
  • septin 7 (Sept7) antibody
  • CDC3 antibody
  • Cdc10 antibody
  • E430034N22 antibody
  • NBLA02942 antibody
  • SEPT7A antibody
  • Septin-7 antibody
  • wu:fb38h06 antibody
  • zgc:56383 antibody

Protein level used designations for anti-Septin 7 (SEPT7) Antibodies

sept7 , septin 7 , septin-7 , cell division cycle 10 , CDC10 protein homolog , CDC10 cell division cycle 10-like , septin-7-like , CDC10 (cell division cycle 10, S. cerevisiae, homolog) , cell division cycle 10 homolog , CDC10 (cell division cycle 10, S.cerevisiae, homolog)

GENE ID SPECIES
394136 Danio rerio
420741 Gallus gallus
444612 Xenopus laevis
463349 Pan troglodytes
677666 Macaca mulatta
100022006 Monodelphis domestica
100173884 Pongo abelii
100216295 Xenopus (Silurana) tropicalis
100350569 Oryctolagus cuniculus
100385961 Callithrix jacchus
100599254 Nomascus leucogenys
989 Homo sapiens
475284 Canis lupus familiaris
100070492 Equus caballus
408000 Bos taurus
235072 Mus musculus
64551 Rattus norvegicus
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