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Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 Proteins (SERPINC1)

The protein encoded by SERPINC1 is a plasma protease inhibitor and a member of the serpin superfamily. Additionally we are shipping Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 Antibodies (268) and Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 Kits (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINC1 11905 P32261
SERPINC1 462 P01008
SERPINC1 304917  
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Top Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 Proteins at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Cynomolgus His tag 50 μg Log in to see 16 Days
$547.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$115.50
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$756.80
Details
HOST_Human Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$198.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Human Human Un-conjugated   100 μg Log in to see 5 to 6 Days
$338.80
Details

SERPINC1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,

Human , , ,
,
Rat (Rattus) ,

Top referenced Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 Proteins

  1. Human SERPINC1 Protein expressed in Human Cells - ABIN2002163 : Chuang, Swanson, Raja, Bock, Olson et al.: The antithrombin P1 residue is important for target proteinase specificity but not for heparin activation of the serpin. Characterization of P1 antithrombin variants with altered proteinase ... in Biochemistry 2001 (PubMed)
    Show all 5 references for ABIN2002163

  2. Cynomolgus SERPINC1 Protein expressed in Human Cells - ABIN3216412 : Oelschläger, Römisch, Staubitz, Stauss, Leithäuser, Tillmanns, Hölschermann: Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cells. in Blood 2002 (PubMed)
    Show all 5 references for ABIN3216412

  3. Human SERPINC1 Protein expressed in Human - ABIN491621 : Gardell, Krueger, Antrilli, Elokdah, Mayer, Orcutt, Crandall, Vlasuk: Neutralization of plasminogen activator inhibitor I (PAI-1) by the synthetic antagonist PAI-749 via a dual mechanism of action. in Molecular pharmacology 2007 (PubMed)

More Proteins for Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) Interaction Partners

Mouse (Murine) Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) interaction partners

  1. RNA interference of Serpinc1 and/or Proc allows for evaluation of the function of these genes in vivo and provides a novel, controlled mouse model for spontaneous venous thrombosis.

Human Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) interaction partners

  1. Elevated levels of circulating microparticles can play a role in carriers of mild and severe inherited thrombophilia resulting from antithrombin deficiency.

  2. The relevance of the vitamin D pathway on the regulation of SERPINC1 was confirmed in a cell model.

  3. The increased SERPINC1 SNP frequency among Han patients receiving heart surgery might contribute to the differences in their perioperative sensitivity to heparin

  4. Patients with low antithrombin III activities presented a higher risk of developing acute kidney injury after cardiac surgery.

  5. Letter/Case Report: novel antithrombin mutation resulting in antithrombin deficiency and arterial/venous thrombosis.

  6. This suggests that allosteric information propagation pathways are present even in the non-activated native form of antithrombin.

  7. analysis of mutations in SERPINC1 with a role in Hereditary antithrombin (AT) deficiency

  8. Polymorphisms in factor V and antithrombin III gene in recurrent pregnancy loss

  9. this is the first report of AT mutations in SERPINC1 gene in Indo (show IDO1 Proteins)-Aryan population where a novel point mutation p.T280A and a novel single nucleotide insertion g.13362_13363insA are reported.

  10. Selective disruption of exosite-mediated regulation of factor IX by heparin and antithrombin can be achieved with preserved or enhanced thrombin (show F2 Proteins) generation capacity.

Cow (Bovine) Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) interaction partners

  1. ATIII may be protective in HIV-1 disease by inhibiting HIV-1 replication

Serine (Or Cysteine) Peptidase Inhibitor, Clade C (Antithrombin), Member 1 (SERPINC1) Protein Profile

Protein Summary

The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.

Gene names and symbols associated with SERPINC1

  • serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1)
  • serpin peptidase inhibitor, clade C (antithrombin), member 1 (SERPINC1)
  • serpin peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1)
  • AI114908 protein
  • ANTITHROMBIN, AT-III protein
  • At-3 protein
  • AT-III protein
  • AT3 protein
  • AT3D protein
  • ATIII protein
  • THPH7 protein

Protein level used designations for SERPINC1

anti-thrombin 3 , antithrombin , antithrombin-III , serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 , serpin C1 , serpin peptidase inhibitor, clade C, member 1 , serpin peptidase inhibitor, clade C (antithrombin), member 1 , antithrombin III , serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 , ATIII

GENE ID SPECIES
11905 Mus musculus
100379601 Cavia porcellus
462 Homo sapiens
480066 Canis lupus familiaris
100061173 Equus caballus
304917 Rattus norvegicus
540261 Bos taurus
100125972 Sus scrofa
443407 Ovis aries
424440 Gallus gallus
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